Kategoria BISAC: Science >> Bioinformatics

Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug...

Designing User Interfaces for an Aging Population: Towards Universal Design presents age-friendly design guidelines that are well-established, agreed-upon, research-based, actionable, and applicable across a variety of modern technology platforms.

The book offers guidance for product engineers, designers, or students who want to produce technological products and online services that can be easily and successfully used by older adults and other populations.

It presents typical age-related characteristics, addressing vision and visual design, hand-eye coordination and...

Data Literacy: How to Make Your Experiments Robust and Reproducible provides an overview of basic concepts and skills in handling data which are common to diverse areas of science. Readers will gain a better grasp of the steps involved in carrying out a scientific study, and will understand some of the factors that make a study robust and reproducible.

The book covers several major modules, such as experimental design, data cleansing and preparation, statistical analysis, data management and reporting. No specialized knowledge of statistics or computer programming is needed...

Next-generation sequencing coupled with high-performance computing methods have revolutionised the field of plant breeding and genetics.

In this timely overview of the field, expert scientists review current developments in next-generation sequencing and bioinformatics and discuss their application in understanding and improving agronomic traits such as yield, drought tolerance and disease resistance. The up-to-date reviews cover genome assembly and annotation, omics technologies, structural variations, abnormal chromosome number, chromosomal rearrangement, copy number variation,...

For the past decade or more, much of cell biology research has been focused on determining the key molecules involved in different cellular processes, an analytical problem that has been amenable to biochemical and genetic approaches. Now, we face an integrative problem of understanding how all of these molecules work together to produce living cells, a challenge that requires using quantitative approaches to model the complex interactions within a cell, and testing those models with careful quantitative measurements.

This book is an introductory overview of the various approaches,...

Bioinformatics Algorithms: Design and Implementation in Python provides a comprehensive book on many of the most important bioinformatics problems, putting forward the best algorithms and showing how to implement them. The book focuses on the use of the Python programming language and its algorithms, which is quickly becoming the most popular language in the bioinformatics field. Readers will find the tools they need to improve their knowledge and skills regarding algorithm development and implementation, and will also uncover prototypes of bioinformatics applications that...

Understanding Cancer from a Systems Biology Point of View: From Observation to Theory and Back starts with a basic question, why do we sometimes observe accelerated metastatic growth after resection of primary tumors? Next, it helps readers understand the systemic nature of cancer and how it affects treatment approaches and decisions. The book puts together aspects of cancer that many readers have most likely never combined, using unfamiliar, novel methods. It is a valuable resource for cancer researchers, cancer biologists, mathematicians and members of the biomedical field who are...