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Aging of the Genome: The Dual Role of DNA in Life and Death
ISBN: 9780198569237 / Angielski / Miękka / 384 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recent advances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead...
Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the ...
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361,39 zł |
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Ancestral Sequence Reconstruction
ISBN: 9780199299188 / Angielski / Twarda / 272 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Ancestral sequence reconstruction is a technique of growing importance in molecular biology and comparative genomics. As a powerful technique for both testing evolutionary and ecological hypotheses as well as uncovering the link between sequence and molecular phenotype, there are potential applications in a number of fields. Beginning with a historical overview of the field including apllications, the discussion then moves into potential applications in drug discovery and the pharmaceutical industry. A section on computational methodology provides a detailed discussion on available methods...
Ancestral sequence reconstruction is a technique of growing importance in molecular biology and comparative genomics. As a powerful technique for both...
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582,75 zł |
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Functional Genomics: A Practical Approach
ISBN: 9780199637744 / Angielski / Miękka / 272 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. With the complete genomes of many organisms now available, and the first draft of the human genome imminent, there is an increasing demand from researchers in a range of disciplines for techniques that will allow them to utilize these resources in their own research. This book provides a comprehensive treatment of the range of methods available for gene and protein expression profiling in a variety of systems. These include large-scale methods, such as cDNA microarrys, serial analysis of gene expression (SAGE) and proteomics, and also methods suitable for non-specialist laboratories, such as...
With the complete genomes of many organisms now available, and the first draft of the human genome imminent, there is an increasing demand from resear...
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283,00 zł |
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DNA Microarrays: A Practical Approach
ISBN: 9780199637768 / Angielski / Miękka / 232 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Written and edited by experts in the field, this book provides valuabl e insight into the remarkable advancement of DNA microarrays. It is es sential for researchers investigating patterns of gene expression and useful for all those interested in the use of biochips.
Written and edited by experts in the field, this book provides valuabl e insight into the remarkable advancement of DNA microarrays. It is es sential ...
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361,39 zł |
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Perspectives on Genetic Discrimination
ISBN: 9781138952447 / Angielski / Miękka / 172 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over the past 15 years, a series of empirical studies in different countries have shown that our increasing genetic knowledge leads to new forms of exclusion, disadvantaging and stigmatization. The spectrum of this "genetic discrimination" ranges from disadvantages at work, via problems with insurance policies, to difficulties with adoption agencies. The empirical studies on the problem of genetic discrimination have not gone unnoticed. Since the beginning of the 1990s, a series of legislative initiatives and statements, both on the national level and on the part of international... Over the past 15 years, a series of empirical studies in different countries have shown that our increasing genetic knowledge leads to new forms of... |
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194,66 zł |
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Haptoglobin Polymorphism among Brahmins of Himachal Pradesh, India
ISBN: 9783659106729 / Angielski / Miękka / 100 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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219,69 zł |
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Styles of Scientific Thought: The German Genetics Community, 1900-1933
ISBN: 9780226318820 / Angielski / Miękka / 444 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this detailed historical and sociological study of the development of scientific ideas, Jonathan Harwood argues that there is no such thing as a unitary scientific method driven by an internal logic. Rather, there are national styles of science that are defined by different values, norms, assumptions, research traditions, and funding patterns.
The first book-length treatment of genetics in Germany, "Styles of Scientific Thought" demonstrates the influence of culture on science by comparing the American with the German scientific traditions. Harwood examines the structure of academic... In this detailed historical and sociological study of the development of scientific ideas, Jonathan Harwood argues that there is no such thing as a un...
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204,96 zł |
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Population Genetics, Molecular Evolution, and the Neutral Theory: Selected Papers
ISBN: 9780226435633 / Angielski / Miękka / 704 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution the neutral theory and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change.
Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and... One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution the n...
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256,20 zł |
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Lords of the Fly: Drosophila Genetics and the Experimental Life
ISBN: 9780226450636 / Angielski / Miękka / 344 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The common fruit fly, Drosophila, has long been one of the most productive of all laboratory animals. From 1910 to 1940, the center of Drosophila culture in America was the school of Thomas Hunt Morgan and his students Alfred Sturtevant and Calvin Bridges. They first created "standard" flies through inbreeding and by organizing a network for exchanging stocks of flies that spread their practices around the world.
In Lords of the Fly, Robert E. Kohler argues that fly laboratories are a special kind of ecological niche in which the wild fruit fly is transformed into... The common fruit fly, Drosophila, has long been one of the most productive of all laboratory animals. From 1910 to 1940, the center of Dros...
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184,46 zł |
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The Shape of Life: Genes, Development, and the Evolution of Animal Form
ISBN: 9780226702667 / Angielski / Miękka / 544 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Rudolf Raff is recognized as a pioneer in evolutionary developmental biology. In their 1983 book, "Embryos, Genes, and Evolution," Raff and co-author Thomas Kaufman proposed a synthesis of developmental and evolutionary biology. In "The Shape of Life," Raff analyzes the rise of this new experimental discipline and lays out new research questions, hypotheses, and approaches to guide its development.
Raff uses the evolution of animal body plans to exemplify the interplay between developmental mechanisms and evolutionary patterns. Animal body plans emerged half a billion years ago. Evolution... Rudolf Raff is recognized as a pioneer in evolutionary developmental biology. In their 1983 book, "Embryos, Genes, and Evolution," Raff and co-author ...
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189,59 zł |
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The Natural History of Inbreeding and Outbreeding: Theoretical and Empirical Perspectives
ISBN: 9780226798554 / Angielski / Miękka / 584 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Inbreeding, the mating of close kin, and outbreeding, the mating of distant relatives or unrelated organisms, have long been important subjects to evolutionary biologists. Inbreeding reduces genetic diversity in a population, increasing the likelihood that genetic defects will become widespread and deprive a population of the diversity it may need to cope with its environment. Most plants and animals have evolved behavioral and morphological mechanisms to avoid inbreeding. However, today many endangered species exist only in small, very isolated populations where inbreeding is...
Inbreeding, the mating of close kin, and outbreeding, the mating of distant relatives or unrelated organisms, have long been important subjects t...
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cena:
281,82 zł |
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Evolution and the Genetics of Populations
ISBN: 9780226910390 / Angielski / Twarda / 520 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. "Wright's views about population genetics and evolution are so fundamental and so comprehensive that every serious student must examine these books firsthand. . . . Publication of this treatise is a major event in evolutionary biology."-Daniel L. Hartl, "BioScience"
"Wright's views about population genetics and evolution are so fundamental and so comprehensive that every serious student must examine these books fi...
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cena:
256,20 zł |
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Evolution and the Genetics of Populations, Volume 3: Experimental Results and Evolutionary Deductions
ISBN: 9780226910406 / Angielski / Miękka / 622 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. "Wright's views about population genetics and evolution are so fundamental and so comprehensive that every serious student must examine these books firsthand. . . . Publication of this treatise is a major event in evolutionary biology."-Daniel L. Hartl, "BioScience"
"Wright's views about population genetics and evolution are so fundamental and so comprehensive that every serious student must examine these books fi...
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cena:
281,82 zł |
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Evolution and the Genetics of Populations
ISBN: 9780226910413 / Angielski / Miękka / 580 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. "Wright's views about population genetics and evolution are so fundamental and so comprehensive that every serious student must examine these books firsthand. . . . Publication of this treatise is a major event in evolutionary biology."-Daniel L. Hartl, "BioScience"
"Wright's views about population genetics and evolution are so fundamental and so comprehensive that every serious student must examine these books fi...
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cena:
281,82 zł |
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Wondergenes: Genetic Enhancement and the Future of Society
ISBN: 9780253342744 / Angielski / Twarda / 226 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Wondergenes not only imagines a future world in which genetic enhancement is the norm, but asserts that this future has already begun. Genetically engineered substances are already in use by athletes, in vitro fertilization already provides the primitive means by which parents can "select" an embryo, and the ability to create new forms of genetically engineered human beings is not far off. What happens when gene therapy becomes gene enhancement? Who will benefit and who might be left behind? What are the costs to our values and beliefs, and to the future of our society? To answer these... Wondergenes not only imagines a future world in which genetic enhancement is the norm, but asserts that this future has already begun. Genetically ... |
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126,51 zł |
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Politics in the Laboratory : The Constitution of Human Genomics
ISBN: 9780299202101 / Angielski / Twarda / 324 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Politics in the Laboratory takes a close look at the ethical, legal, social, constitutional, and political implications of modern biological research. It addresses both biopolicy issues and basic science - including cloning, embryonic stem cell investigations, and experimentation involving the human germline - from the perspective of a political scientist.
Politics in the Laboratory takes a close look at the ethical, legal, social, constitutional, and political implications of modern biological research....
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141,12 zł |
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Reconceiving the Gene: Seymour Benzer's Adventures in Phage Genetics
ISBN: 9780300110784 / Angielski / Twarda / 352 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer's accomplishments are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often than any other individual, he is considered to have led geneticists from the classical gene into the molecular age.
Drawing on Benzer's remarkably complete record of his experiments, his correspondence, and published sources, this book... This book relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial ...
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404,44 zł |
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Genetic Engineering: Principles and Methods
ISBN: 9780306459115 / Angielski / Twarda / 292 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Presents the latest research in genetic engineering. Topics include agrobacterium -mediated horizontal gene transfer, detection of single nucleotide variations, the ribosome as a vehicle for antisense RNA, cloning and expression of large mammalian cDNAs, the use of genetically engineered cells in dr
Presents the latest research in genetic engineering. Topics include agrobacterium -mediated horizontal gene transfer, detection of single nucleotide v...
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cena:
403,47 zł |
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Genetic Engineering: Principles and Methods
ISBN: 9780306461842 / Angielski / Twarda / 278 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Aspects of genetic engineering research emphasized in this volume are applications to plants (crop plants and grass, both important for human needs) and new methodologies, such as Tar cloning, which make it much easier to isolate specific regions from complex genomes. Another subject discussed is linear DNA replication of prokaryotes.
Aspects of genetic engineering research emphasized in this volume are applications to plants (crop plants and grass, both important for human needs) a...
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cena:
403,47 zł |
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Genomes
ISBN: 9780306463600 / Angielski / Twarda / 251 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume brings together the disciplines of plant and animal genome research, and serves as an opportunity for scientists from both fields to compare results, problems and prospects.
This volume brings together the disciplines of plant and animal genome research, and serves as an opportunity for scientists from both fields to compa...
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cena:
605,23 zł |
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