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Adaptive Genetic Variation in the Wild
ISBN: 9780195121834 / Angielski / Twarda / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Two of the great mysteries of biology yet to be explored concern the distribution and abundance of genetic variation in natural populations and the genetic architecture of complex traits. These are tied together by their relationship to natural selection and evolutionary history, and some of the keys to disclosing these secrets lie in the study of wild organisms in their natural environments.
This book, featuring a superb selection of papers from leading authors, summarizes the state of current understanding about the extent of genetic variation within wild populations and the ways to... Two of the great mysteries of biology yet to be explored concern the distribution and abundance of genetic variation in natural populations and the ge...
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757,12 zł |
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The New Healers: The Promise and Problems of Molecular Medicine in the Twenty-First Century
ISBN: 9780195130843 / Angielski / Miękka / 256 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The New Healers outlines the powerful logic behind molecular medicine: everything we know about molecular biology tells us that it can work, and that it will work. Clark introduces us to the scientists working now to map out the entire human genome, taking human beings to a compl etely new level of understanding of our biological selves. Clark also helps us to begin thinking about how we will manage that understanding, and how we will use the information we gain. The New Healers is a cl ear and compelling introduction to this important new frontier of huma n medicine.
The New Healers outlines the powerful logic behind molecular medicine: everything we know about molecular biology tells us that it can work, and that ...
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149,03 zł |
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Phenotypic Integration: Studying the Ecology and Evolution of Complex Phenotypes
ISBN: 9780195160437 / Angielski / Twarda / 464 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A new voice in the nature-nurture debate can be heard at the interface between evolution and development. Phenotypic integration--or, how large numbers of characteristics are related to make up the whole organism, and how these relationships evolve and change their function--is a major growth area in research, attracting the attention of evolutionary biologists, developmental biologists, and geneticists, as well as, more broadly, ecologists, physiologists, and paleontologists. This edited collection presents much of the best and most recent work the topic.
A new voice in the nature-nurture debate can be heard at the interface between evolution and development. Phenotypic integration--or, how large number...
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683,28 zł |
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Evolutionary Genetics: Concepts and Case Studies
ISBN: 9780195168174 / Angielski / Twarda / 608 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Charles Fox and Jason Wolf have brought together leading researchers to produce a cutting-edge primer introducing readers to the major concepts in modern evolutionary genetics. This book spans the continuum of scale, from studies of DNA sequence evolution through proteins and development to multivariate phenotypic evolution, and the continuum of time, from ancient events that lead to current species diversity to the rapid evolution seen over relatively short time scales in experimental evolution studies. Chapters are accessible to an audience lacking extensive background in evolutionaryy...
Charles Fox and Jason Wolf have brought together leading researchers to produce a cutting-edge primer introducing readers to the major concepts in mod...
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321,41 zł |
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When a Gene Makes You Smell Like a Fish: ...and Other Amazing Tales about the Genes in Your Body
ISBN: 9780195169942 / Angielski / Twarda / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. From the gene that causes people to age prematurely to the "bitter gene" that may spawn broccoli haters, this book explores a few of the more exotic locales on the human genome, highlighting some of the tragic and bizarre ways our bodies go wrong when genes fall prey to mutation and the curious ways in which genes have evolved for our survival.
Lisa Seachrist Chiu has a smorgasbord of stories to tell about rare and not so rare genetic quirks. We read about the Dracula Gene, a mutation in zebra fish that causes blood cells to explode on contact with light, and suites of genes that also... From the gene that causes people to age prematurely to the "bitter gene" that may spawn broccoli haters, this book explores a few of the more exotic l...
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350,94 zł |
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The Implicit Genome
ISBN: 9780195172713 / Angielski / Miękka / 400 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. For over half a century, we have been in the thrall of the double-helicaln structure of DNA, which, in an instant, revealed that information can be transferred between generations by a simple rule, A pairs with T, G pairs with C. In its beautiful simplicity, this structure, along with the table of codons worked out in the following decade, had entranced us into believing that we can fully understand the information content of a DNA sequence, simply by treating it as text that is read in a linear fashion. While we have learned much based on this assumption, there is much we have missed. Far...
For over half a century, we have been in the thrall of the double-helicaln structure of DNA, which, in an instant, revealed that information can be tr...
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247,50 zł |
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Systems Biology: Volume II: Networks, Models, and Applications
ISBN: 9780195300802 / Angielski / Twarda / 366 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The advent of genome sequencing and associated technologies has transformed biologists' ability to measure important classes of molecules and their interactions. This expanded cellular view has opened the field to thousands of interactions that previously were outside the researchers' reach. The processing and interpretation of these new vast quantities of interconnected data call for sophisticated mathematical models and computational methods. Systems biology meets this need by combining genomic knowledge with theoretical, experimental and computational approaches from a number of...
The advent of genome sequencing and associated technologies has transformed biologists' ability to measure important classes of molecules and their in...
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cena:
176,11 zł |
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Systems Biology: Volume I: Genomics
ISBN: 9780195300819 / Angielski / Twarda / 336 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The advent of genome sequencing and associated technologies has transformed biologists' ability to measure important classes of molecules and their interactions. This expanded cellular view has opened the field to thousands of interactions that previously were outside the researchers' reach. The processing and interpretation of these new vast quantities of interconnected data call for sophisticated mathematical models and computational methods. Systems biology meets this need by combining genomic knowledge with theoretical, experimental and computational approaches from a number of...
The advent of genome sequencing and associated technologies has transformed biologists' ability to measure important classes of molecules and their in...
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cena:
220,42 zł |
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When a Gene Makes You Smell Like a Fish: ...and Other Amazing Tales about the Genes in Your Body
ISBN: 9780195327069 / Angielski / Miękka / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. From the gene that causes people to age prematurely to the "bitter gene" that may spawn broccoli haters, this book explores a few of the more exotic locales on the human genome, highlighting some of the tragic and bizarre ways our bodies go wrong when genes fall prey to mutation and the curious ways in which genes have evolved for our survival.
Lisa Seachrist Chiu has a smorgasbord of stories to tell about rare and not so rare genetic quirks. We read about the Dracula Gene, a mutation in zebra fish that causes blood cells to explode on contact with light, and suites of genes that also... From the gene that causes people to age prematurely to the "bitter gene" that may spawn broccoli haters, this book explores a few of the more exotic l...
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85,03 zł |
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Microsatellites: Evolution and Applications
ISBN: 9780198504078 / Angielski / Miękka / 368 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Microsatellites are short stretches of repeated DNA that show exceptio nal variability in humans and most other species. This has made micros atellites the genetic marker of choice for most applications, includin g genetic mapping and studies of evolutionary connections between spec ies and populations. This book details the molecular processes which g ive rise to microsatellite DNA and then describes the wide range of ap plications.
Microsatellites are short stretches of repeated DNA that show exceptio nal variability in humans and most other species. This has made micros atellite...
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365,72 zł |
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Computational Text Analysis: For Functional Genomics and Bioinformatics
ISBN: 9780198567400 / Angielski / Twarda / 312 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book brings together the two disparate worlds of computational text analysis and biology and presents some of the latest methods and applications to proteomics, sequence analysis and gene expression data. Modern genomics generates large and comprehensive data sets but their interpretation requires an understanding of a vast number of genes, their complex functions, and interactions. Keeping up with the literature on a single gene is a challenge itself-for thousands of genes it is simply impossible.
Here, Soumya Raychaudhuri presents the techniques and algorithms needed to access and... This book brings together the two disparate worlds of computational text analysis and biology and presents some of the latest methods and applications...
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cena:
510,95 zł |
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Aging of the Genome: The Dual Role of DNA in Life and Death
ISBN: 9780198569237 / Angielski / Miękka / 384 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. Vijg critically reviews the concept of genomic instability as a possible universal cause of aging in the context of a new, holistic understanding of genome functioning in complex organisms resulting from recent advances in functional genomics and systems biology. It provides an up-to-date synthesis of current research, as well as a look ahead...
Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the ...
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365,72 zł |
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Ancestral Sequence Reconstruction
ISBN: 9780199299188 / Angielski / Twarda / 272 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Ancestral sequence reconstruction is a technique of growing importance in molecular biology and comparative genomics. As a powerful technique for both testing evolutionary and ecological hypotheses as well as uncovering the link between sequence and molecular phenotype, there are potential applications in a number of fields. Beginning with a historical overview of the field including apllications, the discussion then moves into potential applications in drug discovery and the pharmaceutical industry. A section on computational methodology provides a detailed discussion on available methods...
Ancestral sequence reconstruction is a technique of growing importance in molecular biology and comparative genomics. As a powerful technique for both...
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597,11 zł |
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Functional Genomics: A Practical Approach
ISBN: 9780199637744 / Angielski / Miękka / 272 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. With the complete genomes of many organisms now available, and the first draft of the human genome imminent, there is an increasing demand from researchers in a range of disciplines for techniques that will allow them to utilize these resources in their own research. This book provides a comprehensive treatment of the range of methods available for gene and protein expression profiling in a variety of systems. These include large-scale methods, such as cDNA microarrys, serial analysis of gene expression (SAGE) and proteomics, and also methods suitable for non-specialist laboratories, such as...
With the complete genomes of many organisms now available, and the first draft of the human genome imminent, there is an increasing demand from resear...
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286,93 zł |
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DNA Microarrays: A Practical Approach
ISBN: 9780199637768 / Angielski / Miękka / 232 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Written and edited by experts in the field, this book provides valuabl e insight into the remarkable advancement of DNA microarrays. It is es sential for researchers investigating patterns of gene expression and useful for all those interested in the use of biochips.
Written and edited by experts in the field, this book provides valuabl e insight into the remarkable advancement of DNA microarrays. It is es sential ...
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cena:
365,72 zł |
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Perspectives on Genetic Discrimination
ISBN: 9781138952447 / Angielski / Miękka / 172 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over the past 15 years, a series of empirical studies in different countries have shown that our increasing genetic knowledge leads to new forms of exclusion, disadvantaging and stigmatization. The spectrum of this "genetic discrimination" ranges from disadvantages at work, via problems with insurance policies, to difficulties with adoption agencies. The empirical studies on the problem of genetic discrimination have not gone unnoticed. Since the beginning of the 1990s, a series of legislative initiatives and statements, both on the national level and on the part of international... Over the past 15 years, a series of empirical studies in different countries have shown that our increasing genetic knowledge leads to new forms of... |
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197,43 zł |
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Haptoglobin Polymorphism among Brahmins of Himachal Pradesh, India
ISBN: 9783659106729 / Angielski / Miękka / 100 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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222,26 zł |
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Styles of Scientific Thought: The German Genetics Community, 1900-1933
ISBN: 9780226318820 / Angielski / Miękka / 444 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this detailed historical and sociological study of the development of scientific ideas, Jonathan Harwood argues that there is no such thing as a unitary scientific method driven by an internal logic. Rather, there are national styles of science that are defined by different values, norms, assumptions, research traditions, and funding patterns.
The first book-length treatment of genetics in Germany, "Styles of Scientific Thought" demonstrates the influence of culture on science by comparing the American with the German scientific traditions. Harwood examines the structure of academic... In this detailed historical and sociological study of the development of scientific ideas, Jonathan Harwood argues that there is no such thing as a un...
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218,82 zł |
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Population Genetics, Molecular Evolution, and the Neutral Theory: Selected Papers
ISBN: 9780226435633 / Angielski / Miękka / 704 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution the neutral theory and his groundbreaking theoretical work in population genetics. This volume collects 57 of Kimura's most important papers and covers forty years of his diverse and original contributions to our understanding of how genetic variation affects evolutionary change.
Kimura's neutral theory, first presented in 1968, challenged the notion that natural selection was the sole directive force in evolution. Arguing that mutations and... One of this century's leading evolutionary biologists, Motoo Kimura revolutionized the field with his random drift theory of molecular evolution the n...
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273,53 zł |
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Lords of the Fly: Drosophila Genetics and the Experimental Life
ISBN: 9780226450636 / Angielski / Miękka / 344 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The common fruit fly, Drosophila, has long been one of the most productive of all laboratory animals. From 1910 to 1940, the center of Drosophila culture in America was the school of Thomas Hunt Morgan and his students Alfred Sturtevant and Calvin Bridges. They first created "standard" flies through inbreeding and by organizing a network for exchanging stocks of flies that spread their practices around the world.
In Lords of the Fly, Robert E. Kohler argues that fly laboratories are a special kind of ecological niche in which the wild fruit fly is transformed into... The common fruit fly, Drosophila, has long been one of the most productive of all laboratory animals. From 1910 to 1940, the center of Dros...
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cena:
196,94 zł |
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