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Chromatin
ISBN: 9781461281238 / Angielski / Miękka / 497 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Contemporary views on the structure and function of chromatin are presented and the history of the development of these ideas as well as the nature of the nucleic acid and protein components of chromatin are reviewed. The structure of chromatin is studied at several levels, and its modes of transcription and replication are analyzed. Chromatin provides researchers with a critical evaluation of current knowledge. It combines much information that has never before been assembled, and evaluates and interrelates it in a critical way. This has not been done before so that readers are not...
Contemporary views on the structure and function of chromatin are presented and the history of the development of these ideas as well as the nature of...
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cena:
529,44 |
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Methods of Hybridoma Formation
ISBN: 9781461291794 / Angielski / Miękka / 504 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Laymen often consider modern laboratory research to be based on an endless array of sophisticated technologies whose complex capabilities are as important to the outcome of any project as the inventiveness and creativity of the scientists who employ them. Scientists at times may share this point of view until they are con- fronted by unexpected findings that demand new approaches, and they discover that yesterday's "sophisticated tools" are today's "blunt instruments." This experience provides a more sobering view of the current state of our scientific methods. It also serves as an impetus...
Laymen often consider modern laboratory research to be based on an endless array of sophisticated technologies whose complex capabilities are as impor...
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cena:
814,55 |
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Volume 4 Immunopathology
ISBN: 9781461592778 / Angielski / Miękka / 440 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio- medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from these cells which constitute the RES. It may now be more fashionable in some quarters to consider these cells as part of what is called the mononuclear phagocytic system or the lymphoreticular system. Nevertheless, because of historical developments and current interest in the subject by investigators from many diverse...
This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Societ...
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cena:
407,25 |
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Cytokines in the Nervous System
ISBN: 9781461596974 / Angielski / Miękka / 207 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. N aney J. Rothwell ytokine neurobiology is now a hot topic Only a few years ago C most neuroscientists were only dimly aware of cytokines and knew little about their function or biological importance. Cytokines, now a huge collection of polypeptides with diverse activities, were until quite recently, studied by those interested in the immune system, inflamma- tion, cancer or infection in peripheral tissues, and did not feature in neuroscience. For example, less than five years ago virtually no refer- ence was made to cytokines in any of the numerous abstracts at the American Society for...
N aney J. Rothwell ytokine neurobiology is now a hot topic Only a few years ago C most neuroscientists were only dimly aware of cytokines and knew li...
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cena:
203,61 |
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Purine Metabolism in Man-IV: Part A: Clinical and Therapeutic Aspects; Regulatory Mechanisms
ISBN: 9781468445558 / Angielski / Miękka / 555 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. These two volumes, entitled "Purine Metabolism in Man IV" con- tain the paper presented at the "IV. International Symposium on Human Purine and Pyrimidine Metabolism," held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet- ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo- lism under normal and pathological conditions has been growing rapid- ly. Apart from the more or less classical topics such as hyperuricae- mia, clinical...
These two volumes, entitled "Purine Metabolism in Man IV" con- tain the paper presented at the "IV. International Symposium on Human Purine and Pyrimi...
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203,61 |
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The Enzymes of Biological Membranes: Volume 3: Membrane Transport (Second Edition)
ISBN: 9781468446036 / Angielski / Miękka / 676 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the first edition of The Enzymes of Biological Membranes. published in four volumes in 1976, we collected the mass of widely scattered information on membrane-linked enzymes and metabolic processes up to about 1975. This was a period of transition from the romantic phase of membrane biochemistry, preoccupied with conceptual developments and the general properties of membranes, to an era of mounting interest in the specific properties of membrane-linked enzymes analyzed from the viewpoints of modem enzymology. The level of sophistication in various areas of membrane research varied widely;...
In the first edition of The Enzymes of Biological Membranes. published in four volumes in 1976, we collected the mass of widely scattered information ...
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cena:
407,25 |
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Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases
ISBN: 9781468496956 / Angielski / Miękka / 578 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Leading scientists summarize the latest findings on signal transduction and cell cycle regulation and describe the effort to design and synthesize inhibiting molecules, as well as to evaluate their biochemical and biological activities. They review the relevant cell surface receptors, their ligands, and their downstream pathways. Also examined are the latest findings on the components of novel signaling networks controlling the activity of nuclear transcription factors and cell cycle regulatory molecules. Cutting-edge and highly suggestive, Signaling Networks and Cell Cycle Control: The...
Leading scientists summarize the latest findings on signal transduction and cell cycle regulation and describe the effort to design and synthesize inh...
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cena:
610,90 |
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Integrin-Ligand Interaction
ISBN: 9781475740660 / Angielski / Miękka / 273 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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407,25 |
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Papillomaviruses in Human Cancer: The Role of E6 and E7 Oncoproteins
ISBN: 9781475761290 / Angielski / Miękka / 173 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Human Papillomavirus has been associated with cancer of the anogenital tract, oral cavity and skin. Two early viral proteins, E6 and E7, play a key role in the malignant transformation of the cell. This book covers different aspects of these two viral oncoproteins. In particular, it focuses on their mechanism in the induction of cellular proliferation and malignant transformation.
Human Papillomavirus has been associated with cancer of the anogenital tract, oral cavity and skin. Two early viral proteins, E6 and E7, play a key ro...
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cena:
203,61 |
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Ras Signaling: Methods and Protocols
ISBN: 9781627037907 / Angielski / Twarda / 425 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Featuring experimental approaches that shed light on the complexity of Ras GTPase biological functions, Ras Signaling: Methods and Protocols contains general overviews and detailed applications of both well-established and recently developed research techniques, including biochemical, biophysical, molecular biology, genetic and behavioral approaches, advanced high resolution fluorescence and electron microscopy imaging and "omics" technologies. Through this, the detailed volume provides information on expression, post-translational modifications, subcellular localization and... Featuring experimental approaches that shed light on the complexity of Ras GTPase biological functions, Ras Signaling: Methods and Protocols... |
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610,90 |
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The Inflammasomes
ISBN: 9783034803434 / Angielski / Miękka / 226 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide...
The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and bi...
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cena:
610,90 |
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DNA Methylation: Molecular Biology and Biological Significance
ISBN: 9783034899154 / Angielski / Miękka / 572 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The occurrence of 5-methylcytosine in DNA was first described in 1948 by Hotchkiss (see first chapter). Recognition of its possible physiologi- cal role in eucaryotes was first suggested in 1964 by Srinivasan and Borek (see first chapter). Since then work in a great many laboratories has established both the ubiquity of 5-methylcytosine and the catholicity of its possible regulatory function. The explosive increase in the number of publications dealing with DNA methylation attests to its importance and makes it impossible to write a comprehensive coverage of the literature within the scope of...
The occurrence of 5-methylcytosine in DNA was first described in 1948 by Hotchkiss (see first chapter). Recognition of its possible physiologi- cal ro...
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203,61 |
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Protein Structure Analysis: Preparation, Characterization, and Microsequencing
ISBN: 9783642477652 / Angielski / Miękka / 316 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. "Protein Structure Analysis - Preparation and Characterization" is a compilation of practical approaches to the structural analysis of proteins and peptides. Here, about 20 authors describe and comment on techniques for sensitive protein purification and analysis. These methods are used worldwide in biochemical and biotechnical research currently being carried out in pharmaceu- tical and biomedical laboratories or protein sequencing facilities. The chapters have been written by scientists with extensive ex- perience in these fields, and the practical parts are well documen- ted so that the...
"Protein Structure Analysis - Preparation and Characterization" is a compilation of practical approaches to the structural analysis of proteins and pe...
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cena:
203,61 |
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Manual on Membrane Lipids
ISBN: 9783642489709 / Angielski / Miękka / 255 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Although previously thought to be merely passive structural components, membrane lipids have recently been found to be actively involved in cellular transport and signal transduction processes. Clear protocols for the study of membrane lipid properties, cellular transport or signal transduction are presented in this manual. Following a short introduction to membrane lipids, techniques for the isolation and extraction of membrane fractions, the analysis of the lipid composition, lipid turnover, and the involvement in signal transduction as well as the preparation of liposomes are described.
Although previously thought to be merely passive structural components, membrane lipids have recently been found to be actively involved in cellular t...
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407,25 |
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Lipid and Protein Traffic: Pathways and Molecular Mechanisms
ISBN: 9783642514654 / Angielski / Miękka / 364 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The meeting on "Molecular Mechanisms of Lipid and Protein Traffic", sponsored by NATO Scientific Affairs Division as an Advanced Study Institute and by the Federation of European Biochemical Societies as a Lecture Course was held in Cargese, France, in June 1997. The program included introductory lectures, specialized up-to-date contributions, poster sessions, tutorials and workshops. Emphasis was laid on the new developments in the field of membrane dynamics, in particular on the insertion and translocation of proteins; on intracellular protein, lipid and membrane traffic and sorting and on...
The meeting on "Molecular Mechanisms of Lipid and Protein Traffic", sponsored by NATO Scientific Affairs Division as an Advanced Study Institute and b...
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203,61 |
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Elektrische Festigkeitslehre
ISBN: 9783642525308 / Niemiecki / Miękka / 488 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfangen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen fur die historische wie auch die disziplingeschichtliche Forschung zur Verfugung, die jeweils im historischen Kontext betrachtet werden mussen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben."
Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfangen des Verlags von 1842 erschienen...
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cena:
304,49 |
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Guidance Cues in the Developing Brain
ISBN: 9783642624261 / Angielski / Miękka / 145 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Many complex molecular interactions are involved in the development of the mammalian brain. Molecules serving as guidance cues for migratory cells, growing axons and for recognition of postsynaptic targets are a major topic for research because they are directly involved in the formation of neuronal circuits, thus creating the foundation for subsequent functional refinement through interactions with the environment. In addition, most guidance cue molecules are also involved in plasticity, damage repair and regeneration in the adult brain. This volume reviews current knowledge on... Many complex molecular interactions are involved in the development of the mammalian brain. Molecules serving as guidance cues for migratory cells,... |
cena:
541,33 |
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Eukaryotism and Symbiosis: Intertaxonic Combination Versus Symbiotic Adaptation
ISBN: 9783642645983 / Angielski / Miękka / 530 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. New techniques in molecular biology have brought spectacular new insights into the study of evolution at the molecular level. This book presents the resulting relatively new concept of "molecular phylogeny", with an overview of current accomplishments and the future direction of research on organelle origin and evolution and the biology of the "higher cell".
New techniques in molecular biology have brought spectacular new insights into the study of evolution at the molecular level. This book presents the r...
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cena:
407,25 |
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Glial-Neuronal Communication in Development and Regeneration
ISBN: 9783642713835 / Angielski / Miękka / 868 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This comprehensive volume is a contribution to a new se ries initiated by the NATO Panel on "Gell to Gell Signals in Plants and Animals." The book reflects the outcome of an NATO work shop and bri ngs to mi nd two im portant questions: consideri ng the mass of relevant I iteratu reavai- able, is there any necessity for a new series of books - and considering the flood of compa rable meetings - is there any point in workshops of this nature and their publication? In order to deal with such questions adequately, much more space would be needed than is available in a foreword. Thus, the answers...
This comprehensive volume is a contribution to a new se ries initiated by the NATO Panel on "Gell to Gell Signals in Plants and Animals." The book ref...
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cena:
407,25 |
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High Performance Liquid Chromatography in Plant Sciences
ISBN: 9783642829536 / Angielski / Miękka / 248 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Modern Methods of Plant Analysis When the handbook Modern Methods of Plant Analysis was first introduced in 1954 the considerations were: 1. the dependence of scientific progress in biology on the improvement of existing and the introduction of new methods; 2. the difficulty in finding many new analytical methods in specialized journals which are normally not accessible to experimental plant biologists; 3. the fact that in the methods sections of papers the description of methods is frequently so compact, or even sometimes so incomplete that it is difficult to reproduce experiments. These...
Modern Methods of Plant Analysis When the handbook Modern Methods of Plant Analysis was first introduced in 1954 the considerations were: 1. the depen...
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cena:
407,25 |
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