Integrin-Ligand Interaction

ISBN-13: 9781475740660 / Angielski / Miękka / 2013 / 273 str.

Johannes A. Elbe

Spis treści

1. Integrins—A Versatile and Old Family of Cell Adhesion Molecules.- 2. Extracellular Matrix Constituents as Integrin Ligands.- 3. Binding Studies of Integrins with Their Respective Ligands.- 4. Recognition Sites of Integrins Within Their Ligands.- 4.1 Recognition Sites of RGD-Dependent Integrins.- 4.2 The Ligand Recognition Motifs of ?4-Integrins and Leukocyte Integrins.- 4.3 Conformation-Dependent Recognition Sites.- 4.4 Snake Venom Disintegrins and Disintegrin-Like Domains: Soluble Antagonists and Cellular Ligands of Integrin Receptors.- 4.5 Microbial Pathogens and Integrin Interactions.- 5.1 Ligand Binding Sites Within the Integrins.- 5.2 Activation States of Integrins.- 5.3 Post-Ligand Binding Events: Outside-In Signaling Through the Integrins.- 6. Integrins During Development.