Kategoria BISAC: Science >> Chemistry - Toxicology

A single-source reference with a broad and holistic overview of nonclinical studies, this book offers critical training material and describes regulations of nonclinical testing through guidelines, models, case studies, practical examples, and worldwide perspectives. The book:

• Provides a complete overview of nonclinical study organization, conduct, and reporting and describes the roles and responsibilities of a Study Director to manage an effective study
• Covers regulatory and scientific concepts, including international testing and Good Laboratory Practice (GLP),...

Biochemical Ecotoxicology: Principles and Methods presents practical approaches to biochemical ecotoxicology experiments for environmental protection and conservation.

With its methodical, stepped approach this essential reference introduces readers to current techniques for toxicity endpoint testing, suitable for laboratories of any size and budget. Each chapter presents a state-of-the-art principle, a quick and inexpensive procedure (including appropriate reagents), case studies, and demonstrations on how to analyze your results.

Generic techniques are...

As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process.

- Guides researchers as to what drug safety experiments are both practical and useful
- Covers a variety of key topics - safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and -omics tools
- Describes what experiments are possible and useful and offers a view into the future, indicating key...

Application, Purification, and Recovery of Ionic Liquids provides a comprehensive overview of the usage of ionic liquids (IL). The book gives a description of the methods used for recovery and purification of ILs, a summary of the economic aspects of using ILs, and a review on the toxicity data of ILs.

It is written for researchers, scientists, and engineers working with ILs, their properties, and usages. The book not only describes the chemical aspects, but the economic and environmental aspects as well, making it of particular interest to professionals applying this...

Genetic Toxicology Testing: A Laboratory Manual presents a practical guide to genetic toxicology testing of chemicals in a GLP environment. The most commonly used assays are described, from laboratory and test design to results analysis. In a methodical manner, individual test methods are described step-by-step, along with equipment, suggested suppliers, recipes for reagents, and evaluation criteria.

An invaluable resource in the lab, this book will help to troubleshoot any assay problems you may encounter to optimise quality and efficiency in your genetic toxicology tests....

Written by leading research scientists, this book integrates current knowledge of toxicology and human health through coverage of environmental toxicants, genetic / epigenetic mechanisms, and carcinogenicity.

• Provides information on lifestyle choices that can reduce cancer risk
• Offers a systematic approach to identify mutagenic, developmental and reproductive toxicants
• Helps readers develop new animal models and tests to assess toxic impacts of mutation and cancer on human health
• Explains specific cellular and molecular targets of known toxicants...

The Indian Nitrogen Assessment: Sources of Reactive Nitrogen, Environmental and Climate Effects, and Management Options and Policies provides a reference for anyone interested in Reactive N, from researchers and students, to environmental managers. Although the main processes that affect the N cycle are well known, this book is focused on the causes and effects of disruption in the N cycle, specifically in India.

The book helps readers gain a precise understanding of the scale of nitrogen use, misuse, and release through various agricultural, industrial, vehicular, and other...

Applications of High Resolution Mass Spectrometry: Food Safety and Pesticide Residue Analysis is the first book to offer complete coverage of all aspects of high resolution mass spectrometry (HRMS) used for the analysis of pesticide residue in food. Aimed at researchers and graduate students in food safety, toxicology, and analytical chemistry, the book equips readers with foundational knowledge of HRMS, including established and state-of-the-art principles and analysis strategies. Additionally, it provides a roadmap for implementation, including discussions of the latest...

In Whitewash, veteran...