Application of Computational Techniques in Pharmacy and Medicine
ISBN: 9789401792561 / Angielski / Twarda / 550 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The proposed volume provides both fundamental and detailed information about the computational and computational-experimental studies which improve our knowledge of how leaving matter functions, the different properties of drugs (including the calculation and the design of new ones), and the creation of completely new ways of treating numerical diseases. Whenever it is possible, the interplay between theory and experiment is provided. The book features computational techniques such as quantum-chemical and molecular dynamic approaches and quantitative structure-activity relationships.
The... The proposed volume provides both fundamental and detailed information about the computational and computational-experimental studies which improve ou...
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cena:
783,57 zł |
Synthetic Biodegradable Polymers
ISBN: 9783642436871 / Angielski / Miękka / 366 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Salen Metal Complexes as Catalysts for the Synthesis of Polycarbonates from Cyclic Ethers and Carbon Dioxide, by Donald J. Darensbourg.- Material Properties of Poly(Propylene Carbonates), by Gerrit. A. Luinstra and Endres Borchardt.- Poly(3-Hydroxybutyrate) from Carbon Monoxide, by Robert Reichardt and Bernhard Rieger. - Ecoflex(R) and Ecovio(R) Biodegradable, Performance-Enabling Plastics, by K. O. Siegenthaler, A. Kunkel, G. Skupin and M. Yamamoto.- Biodegradability of Poly(Vinyl Acetate) and Related Polymers, by Manfred Amann and Oliver Minge.- Recent Developments in Ring-Opening... Salen Metal Complexes as Catalysts for the Synthesis of Polycarbonates from Cyclic Ethers and Carbon Dioxide, by Donald J. Darensbourg.- Material P... |
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1175,38 zł |
Mechanism of Action
ISBN: 9783642460531 / Angielski / Miękka / 785 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The idea for publishing these books on the mechanism of action and on the biosynthesis of antibiotics was born of frustration in our attempts to keep abreast of the literature. Gone were the years when we were able to keep a biblio- graphy on antibiotics and feel confident that we could find everything that was being published on this subject. These fields of investigation were moving for- ward so rapidly and were encompassing so wide a range of specialized areas in microbiology and chemistry that it was almost impossible to keep abreast of developments. In our naivete and enthusiasm,...
The idea for publishing these books on the mechanism of action and on the biosynthesis of antibiotics was born of frustration in our attempts to keep ...
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195,87 zł |
Contract Research and Development Organizations: Their Role in Global Product Development
ISBN: 9781489998903 / Angielski / Miękka / 212 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The last 10 years have seen a seismic shift in therapeutic product development and testing. In both the pharmaceutical (both small and large molecule) and medical device sectors, the vast majority of testing and evaluation of products is not performed within innovator companies, but rather has been outsourced to a growing universe of commercial organizations. The authors both have more than 30 years experience in this field, and both have worked within innovator companies, for CROs, and as consultants in the field. Contract Research and Development Organizations: Their Role in Global Product...
The last 10 years have seen a seismic shift in therapeutic product development and testing. In both the pharmaceutical (both small and large molecule)...
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cena:
587,67 zł |
Medical Applications of Colloids
ISBN: 9781489998019 / Angielski / Miękka / 319 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The important role of ?nely dispersed matter and surfaces in medicine is not always fully understood and appreciated. Speci?cally, ?ne particles (solid or liquid) in the size range of several nanometers to several micrometers have a tremendous effect on our lives, because they can be bene?cial or detrimental to our well-being. Such particles are present in living bodies as red blood cells or cholesterol crystals in the gall bladder. They are ubiquitous in the environment, where they can cause many diseases, such as asbestosis, silicosis, and black lung disease, but they are also used in...
The important role of ?nely dispersed matter and surfaces in medicine is not always fully understood and appreciated. Speci?cally, ?ne particles (soli...
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475,97 zł |
Bioactive Conformation II
ISBN: 9783642447471 / Angielski / Miękka / 233 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts. The volume is still valid and useful after five or ten years. More information, as well as the electronic version of the whole content, is available at: springerlink.com. This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports ... |
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783,57 zł |
Human Chorionic Gonadotropin (Hcg)
ISBN: 9780128007495 / Angielski / Twarda / 446 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Human chorionic gonadotropin (hCG) is produced during pregnancy by the embryo. It promotes progesterone production by corpus luteal cells. It also functions in pregnancy to promote angiogenesis in uterine vasculature, it immuno-blands the invading placental tissue so it is not rejected by the maternal uterine tissues, promotes the growth of the uterus in line with the growth of the fetus, promotes the differentiation of growing cytotrophoblast cells, promotes the quiescence of contractions in the uterine myometrium during the course of pregnancy, and also has function in growth and... Human chorionic gonadotropin (hCG) is produced during pregnancy by the embryo. It promotes progesterone production by corpus luteal cells. It also ... |
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546,71 zł |
Quality Assurance and Quality Control in the Analytical Chemical Laboratory: A Practical Approach, Second Edition
ISBN: 9781138196728 / Angielski / Twarda / 280 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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893,67 zł |
Nanoparticles in Lung Cancer Therapy - Recent Trends
ISBN: 9788132221746 / Angielski / Miękka / 65 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This brief provides an insight into the present scenario of the role of nanotechnology in the diagnosis and treatment of lung cancer at an early stage. Currently, lung cancer is the subject of major concern owing to the very high mortality rate throughout the world. Most of the conventional treatment methods such as surgery, chemotherapy, radiotherapy, etc., fail to prolong life of the patients. Incidents of recurrence are also very common in case of lung cancer. Researchers have shown that nanoparticles may act as a powerful anti cancer tool, especially for lung cancer. Unique surface... This brief provides an insight into the present scenario of the role of nanotechnology in the diagnosis and treatment of lung cancer at an early st... |
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195,87 zł |
Designing Receptors for the Next Generation of Biosensors
ISBN: 9783642427398 / Angielski / Miękka / 264 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Despite achievements in the application of enzymes, antibodies and biological receptors to diagnostics and sensing, the last two decades have also witnessed the emergence of a number of alternative technologies based on synthetic chemistry. This volume shows how synthetic receptors can be designed with characteristics that make them attractive alternatives to biological molecules in the sensory and diagnostics fields, with contributions from leading experts in the area. Subjects covered include synthetic receptors for a range of biomolecules, the use of antimicrobial peptides for the... Despite achievements in the application of enzymes, antibodies and biological receptors to diagnostics and sensing, the last two decades have also ... |
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783,57 zł |
Bacterial Lipopolysaccharides: Structure, Chemical Synthesis, Biogenesis and Interaction with Host Cells
ISBN: 9783709116937 / Angielski / Miękka / 440 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The bacterial lipopolysaccharide also known as endotoxin is exhaustively covered in the present work. Central emphasis is placed upon the fine chemical structure of the lipopolysaccharide and its significance for understanding their activity and function. In particular, the role it plays in the interaction of bacteria with other biological systems is examined. New aspects of their physicochemical biology are introduced and updates to the current knowledge concerning the lipopolysaccharide are provided. This important class of biomolecules has recently attracted the attention of many...
The bacterial lipopolysaccharide also known as endotoxin is exhaustively covered in the present work. Central emphasis is placed upon the fine chemica...
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587,67 zł |
Bio-Inspired Catalysts
ISBN: 9783642420672 / Angielski / Miękka / 115 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In order to meet the ever-increasing demands for enantiopure compounds, heteroge- ous, homogeneous and enzymatic catalysis evolved independently in the past. Although all three approaches have yielded industrially viable processes, the latter two are the most widely used and can be regarded as complementary in many respects. Despite the progress in structural, computational and mechanistic studies, however, to date there is no universal recipe for the optimization of catalytic processes. Thus, a trial-and-error approach remains predominant in catalyst discovery and optimization. With the aim...
In order to meet the ever-increasing demands for enantiopure compounds, heteroge- ous, homogeneous and enzymatic catalysis evolved independently in th...
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cena:
783,57 zł |
Personalizing Precision Medicine: A Global Voyage from Vision to Reality
ISBN: 9781118792117 / Angielski / Miękka / 272 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The author uses decades of experience and interviews with experts in precision medicine to explain past, present, and future of precision medicine. She reviews the full continuum of personalizing precision medicine, including diagnostics, therapeutics, big data, supportive care, regulation, and reimbursement and innovation in precision medicine worldwide.
- Combines a unique cross section of history, current technologies, and future directions for how precision medicine has and will affect people worldwide - Reviews precision medicine around the world, including the US, China,... The author uses decades of experience and interviews with experts in precision medicine to explain past, present, and future of precision medicine. Sh...
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143,60 zł |
Tubulin-Binding Agents: Synthetic, Structural and Mechanistic Insights
ISBN: 9783642435942 / Angielski / Miękka / 331 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. reviews. The SAR data are discussed in light of the structural information available for each agent. The second chapter focuses on the total synthesis of the marine sponge-derived polyketide discodermolide. A comprehensive survey of the synthetic chemistry efforts of several groups over a 14-year period is provided together with a compa- son of the different approaches. The third chapter describes a comprehensive study of the mechanisms of activity of microtubules stabilizing drugs. Thermodynamic, kinetic, structural and fu- tional data on microtubules stabilizing drugs are discussed in an...
reviews. The SAR data are discussed in light of the structural information available for each agent. The second chapter focuses on the total synthesis...
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1175,38 zł |
The Role of Microtubules in Cell Biology, Neurobiology, and Oncology
ISBN: 9781627038614 / Angielski / Miękka / 587 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. I want to thank all who contributed to this first edition for their hard work and professionalism, and especially for their patience. I hope the readers will find this volume as helpful as I have found it. There is no doubt that the family of proteins we call the tubulins and the microtubules that they form when they aggregate are extremely important in the cell and, as we are increasingly learning, important in diseases that afflict so many. This field of investi- tion is a testament to how important both basic and clinical sciences are in understanding disease mechanisms and making inroads...
I want to thank all who contributed to this first edition for their hard work and professionalism, and especially for their patience. I hope the reade...
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cena:
783,57 zł |
Halogen Bonding I: Impact on Materials Chemistry and Life Sciences
ISBN: 9783319140568 / Angielski / Twarda / 280 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The nature and directionality of halogen bonding; the sigma hole, by Timothy Clark, Peter Politzer, Jane S. Murray Solid-state NMR study of halogen-bonded adducts, by David Bryce Infrared and Raman measurements of halogen bonding in cryogenic solutions, by Wouter Herrebout Halogen bonding in the gas phase, by Anthony C. Legon Halogen bonding in solution, Mate Erdelyi Unconventional motifs for halogen bonding, by Kari Rissanen Halogen bonding in supramolecular synthesis, Christer Aakeroy Halogen bond in synthetic organic chemistry, Stefan M. Huber Anion recognition in solution via halogen...
The nature and directionality of halogen bonding; the sigma hole, by Timothy Clark, Peter Politzer, Jane S. Murray Solid-state NMR study of halogen-bo...
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cena:
783,57 zł |
Enzyme- And Transporter-Based Drug-Drug Interactions: Progress and Future Challenges
ISBN: 9781489994899 / Angielski / Miękka / 746 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The goal of this book is to provide a comprehensive view of the scientific bases on issues surrounding the importance of drug-enzyme and drug-transporter interactions and the quantitative predictions of clinically relevant transporter and enzyme based interactions. Although much progress has been made in predicting in vivo metabolic drug interactions based on in vitro studies, the quantitative prediction of clinically relevant transporter-and enzyme based drug interactions remains to be a challenge. The more complex metabolic drug interactions such as inductive, mechanism-based and allosteric...
The goal of this book is to provide a comprehensive view of the scientific bases on issues surrounding the importance of drug-enzyme and drug-transpor...
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cena:
783,57 zł |
Electrochemistry of Immobilized Particles and Droplets: Experiments with Three-Phase Electrodes
ISBN: 9783319108421 / Angielski / Twarda / 327 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This second edition of a successful and highly-accessed monograph has been extended by more than 100 pages. It includes an enlarged coverage of applications for materials characterization and analysis. Also a more detailed description of strategies for determining free energies of ion transfer between miscible liquids is provided. This is now possible with a "third-phase strategy" which the authors explain from theoretical and practical points of view. The book is still the only one detailing strategies for solid state electroanalysis. It also features the specific potential of the techniques...
This second edition of a successful and highly-accessed monograph has been extended by more than 100 pages. It includes an enlarged coverage of applic...
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cena:
391,77 zł |
New Aspects of Zirconium Containing Organic Compounds
ISBN: 9783642424151 / Angielski / Miękka / 175 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Metal carbene complexes have made their way from organometallic curiosities to valuable reagents and catalysts. They offer novel synthetic opportunities in carbon-carbon bond formation based on either carbene-centered reactions or on metal-templated processes which makes them indispensable in modern synthetic methodology. The most prominent metal carbenes are now either commercially available or easy to synthesize and handle with modern laboratory techniques. This volume organized in eight chapters written by the leading scientists in the field illustrates the theoretical background,... Metal carbene complexes have made their way from organometallic curiosities to valuable reagents and catalysts. They offer novel synthetic opportun... |
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cena:
783,57 zł |
Fine Particles in Medicine and Pharmacy
ISBN: 9781489991270 / Angielski / Miękka / 348 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Pharmaceutical manufacture is very exacting - for example, drugs must be uniform in size, shape, efficacy, bioavailability, and safety. The presence of different polymorphs in drug production is a serious problem, since different polymorphs differ in bioavailability, solubility, dissolution rate, chemical and physical stability, melting point, color, filterability, density, and flow properties. Fine Particles in Medicine and Pharmacy discusses particle size, shape, and composition and how they determine the choice of polymorph of a drug.
Pharmaceutical manufacture is very exacting - for example, drugs must be uniform in size, shape, efficacy, bioavailability, and safety. The presence o...
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cena:
391,77 zł |