Kategoria BISAC: Science >> Chemistry - General

Adsorption and desorption in solution play significant roles in separations, detoxification of waste streams, in purification, chromatography, heterogeneous catalysis, metabolism of medicinal drugs, and beyond. Metal-Organic Frameworks (MOFs) are well-ordered 3-dimensional hybrid organic-inorganic polymers which contain metal cations and the structure-building organic "linker" units. Mesoporous MOFs with pore sizes 2-50 nm are particularly suitable for adsorption and adsorption-based separations of large molecules of organic and bio-organic compounds.

Thousands of organic compounds...

Difficult to measure accurately and deal with effectively, organic pollutants continue to be a major hazard in the environment. Significantly expanded, the second edition of Organic Pollutants: An Ecotoxicological Perspective describes the mechanistic basis of ecotoxicology, using major groups of pollutants as illustrative examples, and explores the problem of complex mixtures of chemicals.

New in the Second Edition:

• Expanded coverage of complex pollution problems and the exploitation of recent scientific and technological...

As the shortcomings of purely synthetic approaches to biochemical discovery and development are becoming more apparent, a renaissance of interest in the chemistry of natural products as sources for new compounds is occurring. A unique approach to natural products chemistry, Botanical Miracles: Chemistry of Plants That Changed the World relates applications of plant extracts to the historical progress of civilization. It focuses on selected plants from around the world, connecting their stories and properties to the development of modern marvels such as medicinal compounds, nutrition...

This book provides a comprehensive introduction to advanced drug delivery and targeting, covering their principles, current applications, and potential future developments. This edition has been updated to reflect significant trends and cutting-edge advances that have occurred since the first edition was published. All the original chapters have been retained, but the material therein has been updated. Eight new chapters have been added that deal with entirely new technologies and approaches.

Building on the success of the previous editions, the Textbook of Drug Design and Discovery, Fifth Edition, has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The information is presented in an up-to-date review form with an underlying and fundamental focus on the educational aspects.

Beginning with an introduction to drug design and discovery, the first eight chapters cover molecular recognition, ligand-based drug design,...

Market access is the fourth hurdle in the drug development process and the primary driver for global income of any new drug. Without a strategy in place for pricing, showing value for effectiveness and an understanding of the correct purchasers needs the drug will fail to reach its intended market value. This book is based on an accredited course in this area out of The European Market Access University Diploma (EMAUD) and affiliated with Aix Marseille University.

Key Features:

• The first guide to market access for pharmaceuticals based on tested...

The fifth edition includes new sections on the use of adverse outcome pathways, how climate change changes how we think about toxicology, and a new chapter on contaminants of emerging concern. Additional information is provided on the derivation of exposure-response curves to describe toxicity and they are compared to the use of hypothesis testing. The text is unified around the theme of describing the entire cause-effect pathway from the importance of chemical structure in determining exposure and interaction with receptors to the use of complex systems and hierarchical patch dynamic...