Kategoria BISAC: Science >> Life Sciences - Biology

This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. The chapters written by expert authors who are leaders in the field, provide hints and tricks not available in primary research publications.It is extensively referenced, with useful figures and tables throughout the volume.

• Expert authors who are leaders in the field
• Extensively referenced and useful figures and tables
• Provides hints and tricks to facilitate reproduction of methods

This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. The chapters written by expert authors who are leaders in the field, provide hints and tricks not available in primary research publications.It is extensively referenced, with useful figures and tables throughout the volume.

• Expert authors who are leaders in the field
• Extensively referenced and useful figures and tables
• Provides hints and tricks to facilitate reproduction of methods

In the past several years, there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems. Biothermodynamics, Part C presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions.

The use of thermodynamics in biological research is used as an "energy book-keeping system." While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look...

The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with the 2 previous Computer Methods volumes for the Methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as...

There are numerous excellent reviews on fragment-based drug discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance,...

The global nitrogen cycle is the one most impacted by mankind. The past decade has changed our view on many aspects of the microbial biogeochemical cycles, including the global nitrogen cycle, which is mainly due to tremendous advances in methods, techniques and approaches. Many novel processes and the molecular inventory and organisms that facilitate them have been discovered only within the last 5 to 10 years, and the process is in progress. Research on Nitrification and Related Processes, Part B provides state-of-the-art updates on methods and protocols dealing with the...

This accessible volume sets an ambitious goal: to help people better understand the nature of mental illness. The term itself is a problem for most who believe, consciously or not, that individuals have both a mind and a body. Ronald Chase is interested in the roots of this thinking about mental illness, and finds it in philosophical dualism, famously promoted by Rene Descartes in the seventeenth century. Chase believes this perspective contributes to the stigma associated with mental illness, and argues for a different conceptual understanding. He describes and evaluates several...

The Natural Law of Cycles assembles scientific work from different disciplines to show how research on angular momentum and rotational symmetry can be used to develop a law of energy cycles as a local and global influence. Angular momentum regulates small-scale rotational cycles such as the swimming of fish in water, the running of animals on land, and the flight of birds in air. Also, it regulates large-scale rotation cycles such as global currents of wind and water.

James H. Bunn introduces concepts of symmetry, balance, and angular momentum, showing how together they...

Anthony Walsh bridges the divide separating sociology from biology--a divide created in the late nineteenth century when sociology emerged from the fields of social theory and philosophy. Walsh focuses on the viewpoint held by former American Sociological Association president Douglas Massey: sociologists have allowed the fact that we are social beings to obscure the biological foundations upon which our behaviour ultimately rests.

Walsh argues that sociology has nothing to fear and a wealth of riches to gain if it pays attention to the theories, concepts, and methodologies of the...

Coffee in Health and Disease Prevention presents a comprehensive look at the compounds in coffee, their reported benefits (or toxicity risks) and also explores them on a health-condition specific level, providing researchers and academics with a single-volume resource to help in identifying potential treatment uses. No other book on the market considers all the varieties of coffee in one volume, or takes the disease-focused approach that will assist in directing further research and studies.

The book embraces a holistic approach and effectively investigates coffee and its...

Lactose-Derived Prebiotics: A Process Perspective is the first scientific reference to provide a comprehensive technological overview of the processes to derive oligosaccharides from dairy for use in functional foods. With their combined 90+ years in industry and research, the authors present the functional properties of prebiotics derived from lactose and the production technology required to make them. The book focuses on process engineering and includes an overview of green chemistry processes involving enzyme biocatalysis, providing detailed coverage of the use of whey lactose...