Kategoria BISAC: Science >> Life Sciences - Biology

This book describes the unique characean experimental system, which provides a simplified model for many aspects of the physiology, transport and electrophysiology of higher plants. The first chapter offers a thorough grounding in the morphology, taxonomy and ecology of Characeae plants. Research on characean detached cells in steady state is summarised in Chapter 2, and Chapter 3 covers characean detached cells subjected to calibrated and mostly abiotic types of stress: touch, wounding, voltage clamp to depolarised and hyperpolarised potential difference levels, osmotic and saline stress....

This volume highlights the most interesting biomedical and clinical applications of high-dimensional flow and mass cytometry. It reviews current practical approaches used to perform high-dimensional experiments and addresses key bioinformatic techniques for the analysis of data sets involving dozens of parameters in millions of single cells. Topics include single cell cancer biology; studies of the human immunome; exploration of immunological cell types such as CD8⁺ T cells; decipherment of signaling processes of cancer; mass-tag cellular barcoding; analysis of protein...

After transcription in the nucleus, RNA binding proteins (RBPs) recognize cis-regulatory RNA elements within pre-mRNA sequence to form mRNA-protein (mRNP) complexes. Similarly to DNA binding proteins such as transcription factors that regulate gene expression by binding to DNA elements in the promoters of genes, RBPs regulate the fate of target RNAs by interacting with specific sequences or RNA secondary structural features within the transcribed RNA molecule. The set of functional RNA elements recognized by RBPs within target RNAs and which control the temporal, functional and spatial...

In today's nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios.

Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in...

Prosthetic joint infection (PJI) remains one of the most common causes of revision arthroplasty. It can result in multiple revision surgeries and significant patient morbidity. Periprosthetic infection rates remain around 1-2% after primary total hip and knee arthroplasty and comprise approximately 7-12% of revision cases.

Orthopedic hardware infections are much feared and costly complications that can occur when these devices are implemented both in traumatic cases as well as in joint replacement surgery. Because these infections can lead to great morbidity, it is important to...

Prosthetic joint infection (PJI) remains one of the most common causes of revision arthroplasty. It can result in multiple revision surgeries and significant patient morbidity. Periprosthetic infection rates remain around 1-2% after primary total hip and knee arthroplasty and comprise approximately 7-12% of revision cases.

Orthopedic hardware infections are much feared and costly complications that can occur when these devices are implemented both in traumatic cases as well as in joint replacement surgery. Because these infections can lead to great morbidity, it is important to...