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Mild Stress and Healthy Aging: Applying Hormesis in Aging Research and Interventions
ISBN: 9789048177455 / Angielski / Miękka / 188 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Whereas chronic stress has well known harmful effects, recent research shows that intermittent exposure of cells and organisms to mild stress can improve various biological parameters. This book brings together some of the world leaders in this area of research who present a critical analysis of the ongoing research with respect to the effects and mechanisms of action of various types of mild stress. Novel approaches to improving health and longevity are introduced.
Whereas chronic stress has well known harmful effects, recent research shows that intermittent exposure of cells and organisms to mild stress can impr...
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Ultradian Rhythms from Molecules to Mind: A New Vision of Life
ISBN: 9789048178520 / Angielski / Miękka / 450 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. 5. 1. 1 Biological Rhythms and Clocks From an evolutionary perspective, the adaptation of an organism s behavior to its environment has depended on one of life s fundamental traits: biological rhythm generation. In virtually all light-sensitive organisms from cyanobacteria to humans, biological clocks adapt cyclic physiology to geophysical time with time-keeping properties in the circadian (24 h), ultradian (24 h) domains (Edmunds, 1988; Lloyd, 1998; Lloyd et al., 2001; Lloyd and Murray, 2006; Lloyd, 2007; Pittendrigh, 1993; Sweeney and Hastings, 1960) By definition, all rhythms exhibit...
5. 1. 1 Biological Rhythms and Clocks From an evolutionary perspective, the adaptation of an organism s behavior to its environment has depended on on...
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Signals and Images: Contributions and Contradictions about High Dilution Research
ISBN: 9789048179046 / Angielski / Miękka / 222 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The Groupe International de Recherche sur l Infinitesimal (GIRI) was created in 1986 by Professor Madeleine Bastide and Doctor Rene Halm. Madeleine Bastide was its President for several years. The group comprises actually more than 100 researchers from different disciplines (physicians, chemists, biologists, pharmacologists, physicists, etc. ) from 22 different countries. The original aim, which, for the most part, has now been achieved, was to create a working group to exchange ideas and results concerning the effects of very low doses and high dilutions. Madeleine Bastide then proposed to...
The Groupe International de Recherche sur l Infinitesimal (GIRI) was created in 1986 by Professor Madeleine Bastide and Doctor Rene Halm. Madeleine Ba...
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Mortality and Maldevelopment: Part II: The Saga of Neural Tube Defects
ISBN: 9789048181681 / Angielski / Miękka / 265 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Congenital malformations are worldwide occurrences striking in every condition of society. These severe physical abnormalities which are present at birth and affecting every part of the body happen more often than usually realized, once in every 33 births. The most common, after heart defects, are those of the neural tube (the brain and spinal cord) which happen in as many as one in every 350 births. They have been noted as curiousities in man and beast throughout recorded history and received great attention in our time by various fields of study, for example, their faulty prenatal... Congenital malformations are worldwide occurrences striking in every condition of society. These severe physical abnormalities which are present at... |
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Rabbit Biotechnology: Rabbit Genomics, Transgenesis, Cloning and Models
ISBN: 9789048184767 / Angielski / Miękka / 136 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal models. Although mice including genetically modified mice offer many possibilities, other non-murine species are absolutely required in some circumstances. Rabbit is one of these species, which has been widely used in biomedical studies. This animal is genetically and physiologically closer to humans including cardiovascular system and metabolism characteristics. The rabbit is thus more appropriate than mice to study some diseases such as... The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal... |
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Supramolecular Structure and Function 10
ISBN: 9789400708921 / Angielski / Twarda / 153 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The book is based on lectures presented on the International Summer School on Biophysics held in Croatia in September 2009. The advantage of the School is that it provides advanced training in very broad scope of areas related to biophysics contrary to other similar schools or workshops that are centered mainly on one topic or technique. In this volume, tenth in the row, the papers in the field of biophysics are presented. The topics are biological phenomena from single protein to macromolecular aggregations structure by using variant physical methods (NMR, EPR, FTIR, Mass Spectrometry,...
The book is based on lectures presented on the International Summer School on Biophysics held in Croatia in September 2009. The advantage of the Schoo...
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Biomechanics: Mechanical Properties of Living Tissues
ISBN: 9781441931047 / Angielski / Miękka / 568 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The objective of this book remains the same as that stated in the first edition: to present a comprehensive perspective of biomechanics from the stand point of bioengineering, physiology, and medical science, and to develop mechanics through a sequence of problems and examples. My three-volume set of Bio mechanics has been completed. They are entitled: Biomechanics: Mechanical Properties of Living Tissues; Biodynamics: Circulation; and Biomechanics: Motion, Flow, Stress, and Growth; and this is the first volume. The mechanics prerequisite for all three volumes remains at the level of my book...
The objective of this book remains the same as that stated in the first edition: to present a comprehensive perspective of biomechanics from the stand...
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Multichain Immune Recognition Receptor Signaling: From Spatiotemporal Organization to Human Disease
ISBN: 9781441918871 / Angielski / Miękka / 357 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Immunological recognition is a central feature of the adaptive immunity of vertebrates. With the exception of agnathans, which developed an entirely distinct set of immunologically-specific molecules, all vertebrates use a recognition system based on what Achsah Keegan and I suggested in 1992 be termed multichain immune recognition receptors (MIRRs). MIRRs consist of ligand-binding molecules that are immunoglobulin supergene family members associated with signal transducers and enhancers in such a way as both insure precise ligand recognition, discrimination and ampHfication of the signal....
Immunological recognition is a central feature of the adaptive immunity of vertebrates. With the exception of agnathans, which developed an entirely d...
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Cellular Oscillatory Mechanisms
ISBN: 9781441918888 / Angielski / Miękka / 153 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The papers in this text provide an introduction to a range of both well known and less familiar cellular oscillations, and serves to illustrate the striking richness of cellular dynamics.
The papers in this text provide an introduction to a range of both well known and less familiar cellular oscillations, and serves to illustrate the st...
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Apoptosis: Involvement of Oxidative Stress and Intracellular Ca2+ Homeostasis
ISBN: 9789048182152 / Angielski / Miękka / 235 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Apoptosis: Involvement of Oxidative Stress and Intracellular Ca2+ Homeostasis , presents a concise synthesis of the current knowledge and recent advances in the mechanisms of apoptosis in different cells and the role of oxidative stress and Ca2+ signalling. Particular attention is given to the different features of apoptosis in distinct cell types, ranging from hepatocytes to cardiovascular and blood cells, nervous cells or spermatozoa.Cutting-edge and user-friendly, this volume serves as a comprehensive resource for those interested in the... Apoptosis: Involvement of Oxidative Stress and Intracellular Ca2+ Homeostasis , presents a concise synthesis of the current kno... |
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Current Perspectives in Micrornas (Mirna)
ISBN: 9789048179039 / Angielski / Miękka / 464 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently noticed to manifest clinical and circumstantial malfunction. Numerous non-protein-coding genes are recently found to encode microRNAs, which are responsible for RNA-mediated gene silencing through RNA interference (RNAi)-like pathways. MicroRNAs (miRNAs), small single-stranded 17 25 nucleotide RNAs capable of interfering with intracellular messenger RNAs (mRNAs) that contain either complete or partial complementarity, are useful for the design of new... Nearly 97% of the human genome is the non-coding DNA, which varies from one species to another, and changes in these sequences are frequently notic... |
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Advances in Plant and Animal Boron Nutrition: Proceedings of the 3rd International Symposium on All Aspects of Plant and Animal Boron Nutrition
ISBN: 9789048173563 / Angielski / Miękka / 380 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Boron is one of the essential micronutrients for higher plants growth and development, and more and more studies have been conducted to establish boron as an essential element in animals and humans. This book reviews all aspects of boron research in recent years and is based on the Third International Symposium on all Aspects of Plant and Animal Boron Nutrition which was held in Wuhan, P.R. China. The following issues are discussed:
Boron is one of the essential micronutrients for higher plants growth and development, and more and more studies have been conducted to establish b... |
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P53
ISBN: 9781441982308 / Angielski / Twarda / 200 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Our understanding of human cancer in the past 40 years has been driven by linking innovative concepts and cutting edge technologies to key problems identified by clinical research. Some of the successes in cancer genetics identified from clinical work have been the identification of specific gene deletions in human chromosomes, the use of PCR-based cloning methodologies to identify and clone human cancer genes, the validation of the human cancer genes using transgenetic technologies in the mouse, and the ability to sequence whole genomes that has recently allowed a collation of all somatic...
Our understanding of human cancer in the past 40 years has been driven by linking innovative concepts and cutting edge technologies to key problems id...
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Hepatobiliary and Pancreatic Carcinogenesis in the Hamster
ISBN: 9784431998594 / Angielski / Miękka / 241 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Malignant neoplasms occurring in the biliary tract and pancreas remain a therap- tic challenge. The mechanism of carcinogenesis as well as the growth and spread of these tumors is still poorly understood, making the development of rational tre- ment strategies difficult. In order to improve the clinical results achieved by sur- cal or other medical treatment of such malignant tumors, the establishment of an experimental animal model is critical. For this purpose, attempts were made to induce carcinoma experimentally in the biliary tree and finally an animal model using the hamster was...
Malignant neoplasms occurring in the biliary tract and pancreas remain a therap- tic challenge. The mechanism of carcinogenesis as well as the growth ...
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Bacterial Circadian Programs
ISBN: 9783642100086 / Angielski / Miękka / 333 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since the discovery of circadian rhythms in cyanobacteria in the late 1980s, the field has exploded with new information. The cyanobacterial model system for studying circadian rhythms, "Synechococcus elongatus," has allowed a detailed genetic dissection of the bacterial clock due to the methods currently available in molecular, structural, and evolutionary biology. This book addresses multiple aspects of bacterial circadian programs: the history and background of the cyanobacteria and circadian rhythms in microorganisms, the molecular basis, structure, and evolution of the... Since the discovery of circadian rhythms in cyanobacteria in the late 1980s, the field has exploded with new information. The cyanobacterial model ... |
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Tight Junctions
ISBN: 9781441941152 / Angielski / Miękka / 224 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. ight junctions (TJs) are cell-ceil adhesion belts that encircle epithelial and endothelial cells at the limit between the apical and the lateral Tmembrane. These junctions are crucial for the establishment of separate compartments in multicellular organisms and for the exchange of substances between the internal milieu and the external environment. The perception of TJs has changed over the years. From being regarded as static paracellular seals, they have come to be perceived as dynamic structures that adjust their morphol ogy and function in response to physiological, pharmacological and...
ight junctions (TJs) are cell-ceil adhesion belts that encircle epithelial and endothelial cells at the limit between the apical and the lateral Tmemb...
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Adhesion-Gpcrs: Structure to Function
ISBN: 9781441979124 / Angielski / Twarda / 199 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Upon completion of the human genome project over 800 G protein-coupled receptor 1 (GPCR) genes, subdivided into five categories, were identified. These receptors sense a diverse array of stimuli, including peptides, ions, lipid analogues, light and odour, in a discriminating fashion. Subsequently, they transduce a signal from the ligand-receptor complex into numerous cellular responses. The importance of GPCRs is further reflected in the fact that they constitute the most common target for therapeutic drugs across a 2 wide range of human disorders. Phylogenetic analysis of GPCRs produced the...
Upon completion of the human genome project over 800 G protein-coupled receptor 1 (GPCR) genes, subdivided into five categories, were identified. Thes...
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Histamine in Inflammation
ISBN: 9781441980557 / Angielski / Twarda / 143 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The year 2010 marks the centennial for the identification of histamine and the first glimpse of its many physiological functions. From these initial findings a rich tapestry of research has uncovered roles for histamine in almost every physiological process with new findings emerging every year. These diverse roles of histamine have made for fertile ground for the discovery of novel therapeutics, and these drugs have been so successful that the term "antihistamine" has entered the common lexicon. This volume is an attempt to give a snapshot in time as to the current understanding of the role...
The year 2010 marks the centennial for the identification of histamine and the first glimpse of its many physiological functions. From these initial f...
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Phylogeography of Southern European Refugia: Evolutionary Perspectives on the Origins and Conservation of European Biodiversity
ISBN: 9789048172221 / Angielski / Miękka / 377 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book provides the first synthesis of the remarkable diversity, evolutionary complexity, and conservation importance of the flora and fauna in the Mediterranean region, with emphasis on the three major peninsular refugia. The book highlights biodiversity importance in Southern Europe for European biota conservation, and includes chapters from authorities in phylogeography: John Avise, Remy Petit, Ettore Randi.
This book provides the first synthesis of the remarkable diversity, evolutionary complexity, and conservation importance of the flora and fauna in the...
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Prevention and Treatment of Age-Related Diseases
ISBN: 9789048172177 / Angielski / Miękka / 364 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Biogerontologists are now in a position to construct general principles of aging, and genuine attempts are being made to test and develop effective means of intervention, prevention and treatment of age-related diseases, and for achieving healthy old age. This book takes status of the molecular, cellular, hormonal, nutritional and lifestyle strategies being tested and applied. It comprises inter-dependent chapters written in the form of critical reviews by the world s leading researchers and practitioners in their respective fields. The format of the articles is a semi-academic style in... Biogerontologists are now in a position to construct general principles of aging, and genuine attempts are being made to test and develop effective... |
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