Genetic Medicine: A Logic of Disease
ISBN: 9780801874420 / Angielski / Miękka / 344 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In Genetic Medicine: A Logic of Disease, Barton Childs demonstrates that knowledge of the ways both genes and environment contribute to disease provides a rational basis for medical thinking. This -genetic- medicine, he explains, should help the physician use the results of laboratory tests to perceive the uniqueness of the patient as well as that of the family and the cultural conditions in which the patient's condition arose. Childs thus provides a conceptual framework within which to teach and practice a humane medicine. In Genetic Medicine: A Logic of Disease, Barton Childs demonstrates that knowledge of the ways both genes and environment contribute to dis... |
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193,92 zł |
Genomic Medicine: Articles from the New England Journal of Medicine
ISBN: 9780801879791 / Angielski / Miękka / 208 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. -Fifteen years ago, many questioned the wisdom of sequencing the human genome. There were concerns not only about the technical feasibility of such an effort, but also that its scientific worth would prove too modest to warrant the investment of human and financial capital that the project would require. This collection of essays stands as eloquent testimony to those who overcame such doubts to create, nurture, and finish the sequencing of the human genome in April 2003, a date that will forever stand out in human history. The wide and public availability of the human genome sequence and... -Fifteen years ago, many questioned the wisdom of sequencing the human genome. There were concerns not only about the technical feasibility of such... |
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175,33 zł |
The Troubled Dream of Genetic Medicine: Ethnicity and Innovation in Tay-Sachs, Cystic Fibrosis, and Sickle Cell Disease
ISBN: 9780801883262 / Angielski / Miękka / 264 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Why do racial and ethnic controversies become attached, as they often do, to discussions of modern genetics? How do theories about genetic difference become entangled with political debates about cultural and group differences in America? Such issues are a conspicuous part of the histories of three hereditary diseases: Tay-Sachs, commonly identified with Jewish Americans; cystic fibrosis, often labeled a -Caucasian- disease; and sickle cell disease, widely associated with African Americans. In this captivating account, historians Keith Wailoo and Stephen Pemberton reveal how these... Why do racial and ethnic controversies become attached, as they often do, to discussions of modern genetics? How do theories about genetic differen... |
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132,83 zł |
Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors
ISBN: 9780824700850 / Angielski / Twarda / 448 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An important new collection of clinical and preclinical reports on genetic therapy, this book describes illustrative examples of diseases in which gene-based interventions are presently plausible, and presents case studies of current research using both synthetic oligonucleotides and biological vectors.
Combining the insights of over 50 contributors, Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors An important new collection of clinical and preclinical reports on genetic therapy, this book describes illustrative examples of diseases in which gen...
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1463,73 zł |
Medical Cytogenetics
ISBN: 9780824719999 / Angielski / Twarda / 728 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A discussion of research findings on many important topics in medical genetics - notably FISH (fluorescent in situ hybridization)-based molecular cytogenetic technologies and spectral karyotyping. Designed for cytogeneticists preparing for the certifying examination in clinical cytogenetics offered by the American Board of Medical Genetics (ABMG).
A discussion of research findings on many important topics in medical genetics - notably FISH (fluorescent in situ hybridization)-based molecular cyto...
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757,10 zł |
Neurogenetics: Scientific and Clinical Advances
ISBN: 9780824729424 / Angielski / Twarda / 792 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Standing at the forefront of neurogenetic medicine, this reference supplies the tools and information required by clinicians to become familiar with modern neurogenetic approaches and apply the data gleaned from these technologies to the diagnosis and treatment of neurogenetic disorders, as well as traditionally non-genetic conditions such as Parkinson's and Alzheimer's disease.
Standing at the forefront of neurogenetic medicine, this reference supplies the tools and information required by clinicians to become familiar with m...
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1009,47 zł |
Analytical Techniques in DNA Sequencing
ISBN: 9780824753429 / Angielski / Twarda / 256 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. While one marvels at the DNA generated by the Human Genome Project, perhaps just as significant and fascinating is the development of the amazing analytical technology that has permitted us entry into the genomic era and a whole new level of scientific understanding.
Analytical Techniques in DNA Sequencing takes a look at the various DNA sequencing techniques that were developed and put to use during and after the Human Genome Project. Nunnally makes a special effort to trace the development of this branch of research since the early days of radioisotope sequencing. Special... While one marvels at the DNA generated by the Human Genome Project, perhaps just as significant and fascinating is the development of the amazing anal...
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1211,36 zł |
Neurobehavioral Genetics: Methods and Applications, Second Edition
ISBN: 9780849319037 / Angielski / Twarda / 496 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source. Providing solid historical background, the introductory chapters examine past conceptual streams of behavior genetics. Later chapters discuss the applications of quantitative and molecular genetics in basic and clinical research. This edition offers a contemporary approach to the study of the brain and behavior. It also serves as an excellent resource for investigators who want to incorporate genetic methods into...
Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetic...
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883,29 zł |
DNA Methylation: Approaches, Methods, and Applications
ISBN: 9780849320507 / Angielski / Twarda / 240 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. DNA Methylation: Approaches, Methods and Applications describes the relation DNA methylation has to gene silencing in disease, and explores its promising role in treating cancer. Written by leaders in the field, this exceptional compilation of articles outlines the best techniques to use when addressing questions concerning the cytosine methylation status of genomic DNA. It includes concepts, experimental models, and clinical uses of demethylating agents. The book provides a balance between articles clarifying methodological details and more general review chapters that offer broad biological...
DNA Methylation: Approaches, Methods and Applications describes the relation DNA methylation has to gene silencing in disease, and explores its promis...
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1110,42 zł |
Gaucher Disease
ISBN: 9780849338168 / Angielski / Twarda / 552 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In September of 2007 Gaucher Disease received a commendation in the Haematology category of the 2007 British Medical Association Medical Book Competition Although rare in the general population, Gaucher disease is the most prevalent of the lysosomal storage disorders, making research into this particular orphan disorder an invaluable prototype for the diagnosis, research, and treatment of others. Like many rare conditions, Gaucher disease has benefited from the explosion of medical research in the last decade, the amount of new information on this disease is staggering and the rate of...
In September of 2007 Gaucher Disease received a commendation in the Haematology category of the 2007 British Medical Association Medical Book Competit...
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1160,89 zł |
Access to the Genome: The Challenge to Equality
ISBN: 9780878406784 / Angielski / Miękka / 160 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Completion of the Human Genome Project will make possible a staggering array of new medical technologies, including new diagnostic and screening tests for inherited disorders, gene therapies, and the ability to manipulate a person's inherited, non-disease traits. Most of the attention given to the social implications of these technologies has focused on their potential to harm the individual, for example, by denying employment or insurance. This book explores instead the potential harm to society if we unfairly distribute the enormous benefits of genetic technologies. The resulting... Completion of the Human Genome Project will make possible a staggering array of new medical technologies, including new diagnostic and screening te... |
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255,02 zł |
The Ribosome: Cold Spring Harbor Symposia on Quantitative Biology, Volume LXVI
ISBN: 9780879696207 / Angielski / Miękka / 634 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This is the first book to contain the newly published findings on the structure of the ribosome and discuss their meaning for our understanding of how proteins are made and processed inside the cell. With over 60 contributions from the world's most innovative ribosome biology laboratories, this is the latest volume in the annual series that for over 60 years has provided analysis and interpretation of the most interesting problems in biology.
This is the first book to contain the newly published findings on the structure of the ribosome and discuss their meaning for our understanding of how...
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694,33 zł |
Abraham Lincoln's DNA and Other Adventures in Genetics
ISBN: 9780879696498 / Angielski / Miękka / 339 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Twenty-four true, wide-ranging tales of crime, history, human behavior, illness, and ethics, told from the personal perspective of the author, an eminent physician-lawyer who uses the stories to illustrate the principles of human genetics and to discuss the broader issues.
Twenty-four true, wide-ranging tales of crime, history, human behavior, illness, and ethics, told from the personal perspective of the author, an emin...
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102,31 zł |
The Genome of Homo Sapiens: Cold Spring Harbor Symposia on Quantitative Biology, Volume LXVIII
ISBN: 9780879697099 / Angielski / Twarda / 512 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The Human Genome Project was completed in 2003, 50 years after the discovery of the structure of DNA and 17 years after an influential debate at the annual Cold Spring Harbor Laboratory Symposium about the Project's feasibility. The 2003 Symposium was dedicated to examining what has been learned so far from the human genome sequence. This book contains over sixty contributions from the world's leaders in this field and covers genome structure and evolution, methods of data analysis, lessons from species comparison, and the application of sequence data to the understanding of disease.
The Human Genome Project was completed in 2003, 50 years after the discovery of the structure of DNA and 17 years after an influential debate at the a...
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1861,00 zł |
Is It in Your Genes?: The Influence of Genes on Common Disorders and Diseases That Affect You and Your Family
ISBN: 9780879697211 / Angielski / Miękka / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. One of the most important dividends of the Human Genome Project will be a much greater understanding of the influence of genes on disease and disorders in children (from asthma to autism) and adults (including heart disease, virtually all cancers, and Alzheimer's disease). The nature of genetic risks in families is becoming clearer and this book is written to help people understand them. Philip Reilly, a physician geneticist, who has given hundreds of lectures on this subject, takes a user friendly approach. Drawing on the many questions he has been asked (for example, My sister has multiple...
One of the most important dividends of the Human Genome Project will be a much greater understanding of the influence of genes on disease and disorder...
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36,21 zł |
Gene Isolation and Mapping Protocols
ISBN: 9780896034822 / Angielski / Twarda / 318 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over the past 10 years great progress has been made in the development of efficient techniques for both gene isolation and mapping. The identifica tion and isolation of transcribed sequences from large chromosomal regions are central to the human genome mapping project. Techniques for isolating novel cDNAs have applications both in the overall construction and integra tion of long-range physical and transcription maps and in the identification of disease genes. A number of different techniques for the isolation of cDNAs from mam malian genomes have been developed, including screening "zoo"...
Over the past 10 years great progress has been made in the development of efficient techniques for both gene isolation and mapping. The identifica tio...
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582,32 zł |
DNA Topoisomerase Protocols: Volume II: Enzymology and Drugs
ISBN: 9780896035126 / Angielski / Twarda / 334 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Beginning with the Escherichia coli ? protein, or bacterial DNA topoisomerase I, an ever-increasing number of enzymes have been identified that catalyze changes in the linkage of DNA strands. DNA topoisomerases are ubiquitous in nature and have been shown to play critical roles in most p- cesses involving DNA, including DNA replication, transcription, and rec- bination. These enzymes further constitute the cellular targets of a number of clinically important antibacterial and anticancer agents. Thus, further studies of DNA topology and DNA topoisomerases are critical to advance our und-...
Beginning with the Escherichia coli ? protein, or bacterial DNA topoisomerase I, an ever-increasing number of enzymes have been identified that cataly...
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388,20 zł |
Neurotrophin Protocols
ISBN: 9780896036994 / Angielski / Twarda / 274 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The past decade has seen an extraordinary growth in research interest in neurotrophic factors, and the study of the neurotrophin family has led this activity. Nevertheless, this area of research has often struggled as a result of techniques that were either inadequate or just emerging from other research fields and disciplines. Neurotrophin Protocols has brought together many leaders in the neurotrophin field who detail their special expertise in a wide variety of techniques. Though most procedures are valid across many diff- ent fields of research, some of those described here have been...
The past decade has seen an extraordinary growth in research interest in neurotrophic factors, and the study of the neurotrophin family has led this a...
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cena:
388,20 zł |
Gene Engineering in Endocrinology
ISBN: 9780896037182 / Angielski / Twarda / 428 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. During the past five to ten years, a variety of tools has been developed in the disciplines of both gene engineering, and molecular and structural biology. Some of these advances have permitted scientists not only to identify and characterize genes, but also to target these genes by disruption, thus eliminating their function in living animals, and to det- mine the biological responses to altered gene products. This has particular significance in endocrine systems, in which feedback mechanisms between the hypothalamus, pi- itary, and end organs are critical in normal physiology....
During the past five to ten years, a variety of tools has been developed in the disciplines of both gene engineering, and molecular and structural bio...
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cena:
776,43 zł |
DNA Damage and Repair: Advances from Phage to Humans
ISBN: 9780896038035 / Angielski / Twarda / 412 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Jac A. Nickoloff and Merl F. Hoekstra update and expand their two earlier acclaimed volumes (Vol. I: DNA Repair in Prokaryotes and Lower Eukaryotes and Vol. II: DNA Repair in Higher Eurkaryotes) with cutting-edge reviews by leading authorities of primary experimental findings about DNA repair processes in cancer biology. The reviews cover a wide range of topics from viruses and prokaryotes to higher eukaryotes, and include several new topics, among them the role of recombination in replication of damaged DNA, X-ray crystallographic analysis of DNA repair protein structures, DNA repair...
Jac A. Nickoloff and Merl F. Hoekstra update and expand their two earlier acclaimed volumes (Vol. I: DNA Repair in Prokaryotes and Lower Eukaryotes an...
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cena:
582,32 zł |