Precision Medicine in Stroke
ISBN: 9783030707637 / Angielski / Miękka Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book provides a comprehensive coverage of the state of the art in precision medicine in stroke. It starts by explaining and giving general information about precision medicine. Current applications in different strokes types (ischemic, haemorrhagic) are presented from diagnosis to treatment. In addition, ongoing research in the field (early stroke diagnosis and estimation of prognosis) is extensively discussed. The final part provides an in-depth discussion of how different interdisciplinary areas like artificial intelligence, molecular biology and genetics are contributing to this...
This book provides a comprehensive coverage of the state of the art in precision medicine in stroke. It starts by explaining and giving general inform...
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cena:
392,66 zł |
Regulation of Genome Editing in Human Ips Cells: A Comparative Legal Analysis of National Regulatory Frameworks for Ipsc-Based Cell/Gene Therapies
ISBN: 9783030930226 / Angielski / Twarda Termin realizacji zamówienia: ok. 5-8 dni roboczych. The book provides a concise overview of currently applicable regulatory frameworks of states which are among the world leaders in research and development (R&D) of cell and gene therapies. Developments in genome editing are expected to lead to new possibilities for the treatment of hereditary diseases in humans. The treatment of such often severe but hitherto uncurable diseases can be based on genome-edited induced pluripotent stem cells (iPS cells). Such treatments constitute combined cell/gene therapies. These therapies need to be governed by a regulatory framework which ensures...
The book provides a concise overview of currently applicable regulatory frameworks of states which are among the world leaders in research and de...
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cena:
589,01 zł |
Anticipatory Ethics and the Use of Crispr in Humans
ISBN: 9783030983673 / Angielski / Twarda Termin realizacji zamówienia: ok. 5-8 dni roboczych. The future of gene editing in humans will involve the use of CRISPR. How we think about the combination of the scientific, ethical, and moral aspects of this technology is paramount to the success or failure of CRISPR in humans. Unfortunately, the current scientific discussion around CRISPR in humans has left ethics trailing behind due to the rapid pace of innovation. New modes of ethics and stakeholder participation are needed to keep pace with rapid scientific advances and provide the necessary policy and ethical frameworks necessary to help CRISPR flourish as an important health care... The future of gene editing in humans will involve the use of CRISPR. How we think about the combination of the scientific, ethical, and moral aspec... |
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cena:
510,47 zł |
TET Proteins and DNA Demethylation: Methods and Protocols
ISBN: 9781071612965 / Angielski / Miękka Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume explores the latest methods used to study various aspects of TET proteins and their biology. Chapters in this book are divided into five parts. Part One describes technologies aimed at detecting and quantifying DNA methylation turnover using massively parallel sequencing, ELISA, and mass spectrometry approaches. Part Two looks at data analyses protocols for distinguishing acting versus passive DNA demethylation and estimation of 5mC and 5hmC levels. Part Three deals with a new topic that takes advantage of modified CRISPR/Cas9 genome editing systems to target DNA demethylation... This volume explores the latest methods used to study various aspects of TET proteins and their biology. Chapters in this book are divided into fiv... |
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cena:
510,47 zł |
The Myc Gene: Methods and Protocols
ISBN: 9781071614785 / Angielski / Miękka Termin realizacji zamówienia: ok. 5-8 dni roboczych. This second edition provides new and updated chapters detailing recent advances in MYC research and current techniques. Chapters guide readers through protocols on how to express and purify MYC protein, X-ray crystallography, NMR, techniques to study how MYC is modified, apoptosis, senescence, proliferation, metabolic changes, translation, tumorigenesis,reprogramming, and clinical application of MYC studies.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the... This second edition provides new and updated chapters detailing recent advances in MYC research and current techniques. Chapte... |
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cena:
510,47 zł |
Human Genome Structure, Function and Clinical Considerations
ISBN: 9783030731533 / Angielski / Miękka Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book provides a detailed evidence-based overview of the latest developments in how the structure of the human genome is relevant to the health professional. It features comprehensive reviews of genome science including human chromosomal and mitochondrial DNA structure, protein-coding and noncoding genes, and the diverse classes of repeat elements of the human genome. These concepts are then built upon to provide context as to how they functionally relate to differences in phenotypic traits that can be observed in human populations. Guidance is also provided on how this information can... This book provides a detailed evidence-based overview of the latest developments in how the structure of the human genome is relevant to the health... |
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cena:
392,66 zł |
Long Non-Coding RNAs in Cancer
ISBN: 9781071615836 / Angielski / Miękka Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization. Chapters guide readers through identification of lncRNA expression signatures in cancer tissue or liquid biopsies by RNAseq, single Cell RNAseq, Phospho RNAseq or Nanopore Sequencing techniques; validation of lncRNA signatures by Real time PCR, digital PCR or in situ hybridization; and functional analysis by siRNA or CRISPR based methods for lncRNA silencing or overexpression. Lipid based nanoparticles for delivery of siRNAs in... This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional ... |
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cena:
471,20 zł |
Directed Evolution: Methods and Protocols
ISBN: 9781071621516 / Angielski / Twarda Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume explores the latest techniques used by researchers to study directed evolution (DE) at each stage of the Design-Build-Test-Learn cycle. Chapters in this book cover topics such as designing overlap extension PCR primers for protein mutagenesis; antha-guided automation of Darwin assembly for the construction of bespoke gene libraries; rapid cloning of random mutagenesis libraries using PTO-Quickstep; and DE of glycosyltransferases by a single-cell screening method. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions... This volume explores the latest techniques used by researchers to study directed evolution (DE) at each stage of the Design-Build-Test-Learn cycle.... |
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cena:
863,90 zł |
Enhancers and Promoters: Methods and Protocols
ISBN: 9781071615997 / Angielski / Miękka Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume contains cutting-edge techniques to study the function of enhancers and promoters in depth. Chapters are divided into six sections and describe enhancer-promoter transcripts, nucleosome occupancy, DNA accessibility, chromatin interactions, protein-DNA interactions, functional analyses, and DNA methylation assays. Written in the Methods in Molecular Biology series format, chapters include comprehensive introductions, lists of the necessary materials and reagents, step-by-step laboratory protocols, and useful suggestions for troubleshooting. Authoritative...This volume contains cutting-edge techniques to study the function of enhancers and promoters in depth. Chapters are divided into six sections and ... |
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cena:
510,47 zł |
DNA Modification Detection Methods
ISBN: 9781071612316 / Angielski / Miękka Termin realizacji zamówienia: ok. 5-8 dni roboczych. Understanding the functional roles of DNA modifications relies on the accurate detection, quantification, and mapping of DNA modifications. Methods for deciphering DNA modifications have substantially improved over the last several years, which greatly revolutionize the field of DNA modifications. In addition to DNA cytosine methylation (5-methylcytosine, 5mC), the best-characterized epigenetic modification, many new modifications have been discovered to present in DNA in recent years. This book provides a comprehensive overview of available techniques and methods... Understanding the functional roles of DNA modifications relies on the accurate detection, quantification, and mapping of DNA modifications. Methods... |
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cena:
510,47 zł |
Yeast Metabolic Engineering: Methods and Protocols
ISBN: 9781071623985 / Angielski / Twarda Termin realizacji zamówienia: ok. 5-8 dni roboczych. This second edition volume expands on the previous edition with new and updated chapters on the latest developments in the study of yeast within the biotechnology field. The chapters in this book cover topics such as transformation protocols for genetic engineering of Saccaromyces cerevisiae and Komagataella spp.; an overview of selection markers, promoters, and strains used for metabolic engineering of S. cerevisiae, P. pastoris, and Z. bailii; the use of yeast in CRISPR/Cas9 technology; tools to study metabolic pathway...
This second edition volume expands on the previous edition with new and updated chapters on the latest developments in the study of yeast within ...
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cena:
863,90 zł |
Current Thoughts on Dementia: From Risk Factors to Therapeutic Interventions
ISBN: 9789811676055 / Angielski / Twarda Termin realizacji zamówienia: ok. 5-8 dni roboczych. This informative book discusses the latest research on the risk factors and therapeutics in dementia. WHO calls dementia a public health priority. Dementia manifests as a group of symptoms associated with decline in memory or other thinking skills and is severe enough to reduce a person's ability to perform everyday activities. It occurs frequently among elderly people, but it is not necessarily part of the normal aging process. The book has been divided into two broad sections. The first section reviews the risk factors involved in developing dementia, including various medical... This informative book discusses the latest research on the risk factors and therapeutics in dementia. WHO calls dementia a public health priority. ... |
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cena:
903,17 zł |
Gentechnik in Der Medizin - Hintergründe, Chancen Und Risiken
ISBN: 9783662656518 / Niemiecki / Miękka Termin realizacji zamówienia: ok. 5-8 dni roboczych. Bettina Heberer gibt interessierten Laien einen Einblick in die Verwendung von Gentechnik in der Medizin. Die Autorin erläutert die verschiedenen Anwendungsbereiche der Gendiagnostik und Gentherapie. Zugelassene sowie potentielle zukünftige Therapiemöglichkeiten werden ebenso behandelt wie rechtliche Grundlagen. Eine Diskussion der Chancen und Risiken, die mit der Entwicklung neuer Technologien einhergehen, runden das Werk ab.
Bettina Heberer gibt interessierten Laien einen Einblick in die Verwendung von Gentechnik in der Medizin. Die Autorin erläutert die verschiedenen Anw...
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cena:
55,02 zł |
Taurine 12: A Conditionally Essential Amino Acid
ISBN: 9783030933364 / Angielski / Twarda / 608 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume gathers a selection of original articles and reviews on timely topics about the application of Taurine in human health written by members of the International Taurine Society, including COVID-19, cancer, heart disease, and diabetes, among others. Chapters are written by Taurine experts across the globe in North and South America, Asia, and Europe. A majority of the articles are based on original studies recently carried out in individual laboratories worldwide. The book is divided into eight parts, each covering a unique aspect of Taurine. Each section will highlight new research...
This volume gathers a selection of original articles and reviews on timely topics about the application of Taurine in human health written by members ...
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cena:
785,36 zł |
Ferroptosis: Mechanism and Diseases
ISBN: 9783030620288 / Angielski / Miękka Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book focuses on the emerging role of ferroptosis in human diseases. It gives a detailed perspective on how to induce or suppress ferroptosis to treat challenging conditions such as infectious diseases, including COVID-19, tuberculosis, parasitic diseases and cancer. The book serves as a practical guide by providing a valuable collection of all currently known activators or inhibitors of ferroptosis. It will enable readers to choose molecules for experimental design for in vitro and in vivo studies of ferroptosis. Furthermore, this volume highlights the aspects of iron... This book focuses on the emerging role of ferroptosis in human diseases. It gives a detailed perspective on how to induce or suppress ferroptosis t... |
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cena:
510,47 zł |
Ovarian Cancer Biomarkers: Mapping to Improve Outcomes
ISBN: 9789811618758 / Angielski / Miękka Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profiling in the advancement of precision medicine. The initial chapter discusses our current understanding of the origin, development, progression and tumorigenesis of ovarian cancer. In turn, the book highlights the development of resistance, disease occurrence, and poor prognosis that are the hallmarks of ovarian cancer. The book then reviews the role of deep molecular and cellular profiling to overcome challenges that are associated with the...
This book comprehensively summarizes the biology, etiology, and pathology of ovarian cancer and explores the role of deep molecular and cellular profi...
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cena:
431,93 zł |
DNA Methyltransferases - Role and Function
ISBN: 9783031114533 / Angielski / Twarda / 562 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This 2ndedition of the book on DNA methyltransferases has been comprehensively updated to reflect many novel research findings regarding the structure, function, and technology of these enzymes that have emerged over the past 6 years.Like the previous edition, this 2ndedition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological roles in bacteria, humans and plants. It also discusses the biological processes of reading DNA methylation and the mechanisms of DNA demethylation. This volume highlights the newest findings on DNA...
This 2ndedition of the book on DNA methyltransferases has been comprehensively updated to reflect many novel research findings regarding the structure...
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cena:
903,17 zł |
Glycosignals in Cancer: Molecular Assembly and Recognition
ISBN: 9789811977312 / Angielski / Twarda / 291 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book, now in an extensively revised second edition, provides a comprehensive summary of the latest knowledge regarding glycosignals and a thorough analysis of their involvement in not only cancers but also other refractory conditions such as chronic inflammatory disorders. Many relevant topics are covered, including the search for novel tumor epitopes related to carbohydrates, the assembly of glycoconjugates, the modulation of signaling pathways by glycosylation, and interactions between complex carbohydrates and their recognition molecules. The role of various research approaches, for...
This book, now in an extensively revised second edition, provides a comprehensive summary of the latest knowledge regarding glycosignals and a thoroug...
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cena:
589,01 zł |
Protocols in Advanced Genomics and Allied Techniques
ISBN: 9781071618202 / Angielski / Miękka / 720 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This laboratory manual includes the latest tools and techniques involved in genomic research. It starts with an introductory chapter on genomics and the various tools and applications involved. The initial chapters present protocols for basic techniques such as DNA isolation, electrophoresis, PCR, cDNA synthesis etc. The book then goes on to describe more advanced techniques such as next-generation sequencing, exome sequencing, use of RNAi, RNAseq, genome editing, single cell genomics etc. Each topic includes a brief description, information on the principles involved, materials & methods,...
This laboratory manual includes the latest tools and techniques involved in genomic research. It starts with an introductory chapter on genomics and t...
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cena:
451,56 zł |
Progress in Heritable Soft Connective Tissue Diseases
ISBN: 9783030806163 / Angielski / Miękka / 343 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume represents a substantially revised and updated 2nd edition of a reference handbook on major structural components of soft connective tissues and a whole slew of heritable diseases of soft connective tissues. The number of clearly identifiable and distinct disorders has grown somewhat since the 1st edition in 2014, e.g., Ehlers-Danlos syndrome has now 13 entities. A brand new syndrome, Meester Loeys syndrome carrying the name of Bart Loeys was added as a companion to Loeys-Dietz syndrome. Numerous variations of cutis laxa and joint mobility disorders have been discovered taking...
This volume represents a substantially revised and updated 2nd edition of a reference handbook on major structural components of soft connective tissu...
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cena:
471,20 zł |