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Evolutionary Genetics of Invertebrate Behavior
ISBN: 9780306424885 / Angielski / Twarda / 336 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the preface to Sir Vincent B. Wigglesworth's classic 1939 book on insect physiology he asserted that insects provide an ideal medium in which to study all the problems of physiology. A strong case can be made as well for the use of insects as significant systems for the study of behavior and genetics. Contributions to genetics through decades of research on Drosophila species have made this small fly the most important metazoan in genetics research. At the same time, population and behavioral research on insects and other invertebrates have provid ed new perspectives that can be combined...
In the preface to Sir Vincent B. Wigglesworth's classic 1939 book on insect physiology he asserted that insects provide an ideal medium in which to st...
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Molecular Basis of Human Cancer
ISBN: 9780306440182 / Angielski / Twarda / 216 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. During May 21-June 1 1990, the eleventh course of the International School of Pure and Applied Biostructure, a NATO Advanced Study Institute, was held at the Ettore Majorana Center for Scientific Culture in Erice, Italy, co-sponsored by the Italian Ministry of Universities and of Scientific and Technological Research, the North Atlantic Treaty Organization, the Italian National Research Council, the Sicilian Regional Government and Technobiochip. The subject of the course was "Molecular Basis of Human Cancer" with participants selected worldwide from 15 different countries. The purpose of the...
During May 21-June 1 1990, the eleventh course of the International School of Pure and Applied Biostructure, a NATO Advanced Study Institute, was held...
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Genetic Engineering: Principles and Methods
ISBN: 9780306445262 / Angielski / Twarda / 248 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The current volume covers human gene therapy, improving the nutritional value of maize, restriction-modification enzymes, and eight other subjects.
The current volume covers human gene therapy, improving the nutritional value of maize, restriction-modification enzymes, and eight other subjects.
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Genomes of Plants and Animals: 21st Stadler Genetics Symposium
ISBN: 9780306453724 / Angielski / Twarda / 320 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume brings together the disciplines of plant and animal genome research, and serves as an opportunity for scientists from both fields to compare results, problems and prospects.
This volume brings together the disciplines of plant and animal genome research, and serves as an opportunity for scientists from both fields to compa...
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Reproductive Toxicology: In Vitro Germ Cell Developmental Toxicology, from Science to Social and Industrial Demand
ISBN: 9780306460258 / Angielski / Twarda / 223 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Numerous reports demonstrate that the reproductive system could be affected by multiple potential toxicological agents. The volume includes different aspects of the development of new approaches to in vitro testing using sperm cells and systems involved on reproduction in mammals. Comparative analysis of in vivo and in vitro methods has been included to take steps towards the further development of and applications of new systems for germline toxicology.
Numerous reports demonstrate that the reproductive system could be affected by multiple potential toxicological agents. The volume includes different ...
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Molecular and Cellular Mechanisms of Neuronal Plasticity: Basic and Clinical Implications
ISBN: 9780306460401 / Angielski / Twarda / 229 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Numerous studies have proven the biological basis of memory formation and have begun to identify the biochemical traces and cellular circuits that are formed by experience, and which participate int the storage of information in the brain, its retention for long durations, and its retrieval upon demand. Cells in the nervous system have the capability of undergoing extremely long-lasting alterations in response to hormonal, pharmacological, and environmental stimulations. The mechanisms underlying this neuronal plasticity are activated by experiential inputs and operate in the process of...
Numerous studies have proven the biological basis of memory formation and have begun to identify the biochemical traces and cellular circuits that are...
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Phospholipid Metabolism in Apoptosis
ISBN: 9780306467820 / Angielski / Twarda / 340 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The last few years have witnessed an explosion of both interest and knowledge about apoptosis, the process by which a cell actively commits suicide. The number of publications on the topic has increased from nothing in the early 1980s to more than 10,000 papers annually today. It is now well recognized that apoptosis is essential in many aspects of normal development and is required for maintaining tissue homeostasis. The idea that life requires death seems somewhat paradoxical, but cell suicide is essential for an animal to survive. For example, without selective destruction of "non-self" T...
The last few years have witnessed an explosion of both interest and knowledge about apoptosis, the process by which a cell actively commits suicide. T...
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Advances in Male Mediated Developmental Toxicity
ISBN: 9780306474804 / Angielski / Twarda / 300 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It is nearly a decade since the first Male Mediated Developmental Toxicity conference was held in Pittsburgh. The continuing public/scientific interest, growing amounts of animal data, introduction of innovative technologies, and increasing quantity of human epidemiological studies all suggest that male-mediated developmental toxicity is of major concern. A number of researchers concluded that a Second International Confer ence on Male Mediated Developmental Toxicity was necessary. The ensuing volume is particularly timely because it impacts on areas of special emphasis in many countries,...
It is nearly a decade since the first Male Mediated Developmental Toxicity conference was held in Pittsburgh. The continuing public/scientific interes...
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Autotrophic Microbiology and One-Carbon Metabolism: Volume I
ISBN: 9780792306566 / Angielski / Twarda / 232 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Autotrophic and methylotrophic microorganisms are able to grow at the expense of one-carbon compounds (e.g. carbon dioxide, formaldehyde) as the principal carbon sources for the synthesis of cell material, using light, inorganic compounds or one-carbon compounds as energy sources. The study of the special adaptations required in aerobic and anaerobic microorganisms to sustain an autotrophic or methylotrophic mode of life is a fascinating field of research for scientists from various disciplines. Current research efforts not only focus on fundamental aspects, i.e. metabolic pathways and their...
Autotrophic and methylotrophic microorganisms are able to grow at the expense of one-carbon compounds (e.g. carbon dioxide, formaldehyde) as the princ...
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Molecular Cardiology for the Cardiologists
ISBN: 9780792336228 / Angielski / Twarda / 250 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Molecular Cardiology for the Cardiologist provides a short, easily readable summary of what the new biology brings to cardiology. With this in mind, special efforts have been made to present many comprehensive schemes and drawings, as well as teaching tables.
The five parts of the book provide a general introduction to the new language of biology; the normal structure of the heart and blood vessels; the physiopathology and the new therapeutic avenues that have been opened up by the new biology. A concise summary of the keys that assist the cardiologist or student who... Molecular Cardiology for the Cardiologist provides a short, easily readable summary of what the new biology brings to cardiology. With this i...
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Triple Helix Forming Oligonucleotides
ISBN: 9780792384182 / Angielski / Twarda / 297 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Sequence-specific DNA binding ligands, amongst which triple helix forming oligonucleotides are the most efficient as yet, represent promising tools in a number of fields. One of their most promising applications is as antiviral tools: they can specifically target a viral gene, even if it is integrated into the host genome, and be used to specifically inactivate the viral gene or even destroy the cells harboring this gene. However, from science fiction to science there remains a gap; and we are at the moment on the threshold of this fascinating field. Triple Helix Forming...
Sequence-specific DNA binding ligands, amongst which triple helix forming oligonucleotides are the most efficient as yet, represent promising tools in...
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Applications of Antisense Therapies to Restenosis
ISBN: 9780792384236 / Angielski / Twarda / 184 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Restenosis, the proliferation of smooth muscle cells (SMC) that line blood vessels, often follows angioplasty. Despite advances in cardiology, restenosis continues to affect up to 40% of the over 500,000 patients who undergo angioplasty each year. Applications of Antisense Therapies to Restenosis is the first volume to address the potential of using antisense therapies to inhibit the restenosis that occurs after percutaneous transluminal angioplasty and coronary stenting. The work critically examines the application of various antisense therapies for inhibiting restenosis.
Restenosis, the proliferation of smooth muscle cells (SMC) that line blood vessels, often follows angioplasty. Despite advances in cardiology, resteno...
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Gene Targeting Protocols
ISBN: 9780896033603 / Angielski / Twarda / 233 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The potential now exists in many experimental systems to transfer a cloned, modified gene back into the genome of the host organism. In the ideal situation, the cloned gene is returned to its homologous location in the genome and becomes inserted at the target locus. This process is a controlled means for the repair of DNA damage and ensures accurate chromosome disjunction during meiosis. The paradigm for thinking about the mechanism of this p- cess has emerged primarily from two sources: (1) The principles of reaction mechanics have come from detailed biochemical analyses of the RecA protein...
The potential now exists in many experimental systems to transfer a cloned, modified gene back into the genome of the host organism. In the ideal situ...
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Celiac Disease: Methods and Protocols
ISBN: 9780896036505 / Angielski / Twarda / 288 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Research into gluten sensitivity has never been more popular nor more exciting. Thus a call for a new book, Celiac Disease: Methods and Protocols, devoted entirely to techniques and technology seemed a most appropriate undertaking. I am therefore grateful to Professor J. M. Walker for inviting me to complete this task for Humana Press. To do this would have been imp- sible without the contributions of friends and colleagues from around the world who have devoted so much interest to the project. It has also been necessary for them to master the unique chapter-writing skills required of every...
Research into gluten sensitivity has never been more popular nor more exciting. Thus a call for a new book, Celiac Disease: Methods and Protocols, dev...
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Muscular Dystrophy: Methods and Protocols
ISBN: 9780896036956 / Angielski / Twarda / 458 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The term "muscular dystrophy" (MD) describes a group of primary genetic disorders of muscle that often have a distinctive and recognizable clinical p- notype, accompanied by characteristic, but frequently not pathognomonic, pathological features. Research into the molecular basis of the MDs by a c- bination of positional cloning and candidate gene analysis has provided the basis for a reclassification of these disorders, with genetic and protein data augmenting traditional clinically based nomenclature. These findings have brought insights into the molecular pathogenesis of MD, with an...
The term "muscular dystrophy" (MD) describes a group of primary genetic disorders of muscle that often have a distinctive and recognizable clinical p-...
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Tumor Suppressor Genes: Volume 1: Pathways and Isolation Strategies
ISBN: 9780896039865 / Angielski / Twarda / 520 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It has become clear that tumors arise from excessive cell proliferation and a c- responding reduction in cell death. Tumors result from the successive accumulation of mutations in key regulatory target genes over time. During the 1980s, a number of oncogenes were characterized, whereas from the 1990s to the present, the emphasis shifted to tumor suppressor genes (TSGs). It has become clear that oncogenes and tumor suppressor genes function in the same pathways, providing positive and ne- tive growth regulatory activities. The signaling pathways controlled by these genes involve virtually...
It has become clear that tumors arise from excessive cell proliferation and a c- responding reduction in cell death. Tumors result from the successive...
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Genome Evolution: Gene and Genome Duplications and the Origin of Novel Gene Functions
ISBN: 9781402010217 / Angielski / Twarda / 237 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the years since the publication of Susumu Ohno's 1970 landmark book Evolution by gene duplication tremendous advances have been made in molecular biology and especially in genomics. Studies of genome structure and function prerequisite to testing hypotheses of genome evolution were all but impossible until recent methodological advances. This book evaluates newly generated empirical evidence as it pertains to theories of genomic evolutionary patterns and processes. Tests of hypotheses using analyses of complete genomes, interpreted in a phylogenetic context,... In the years since the publication of Susumu Ohno's 1970 landmark book Evolution by gene duplication tremendous advances have been... |
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Modulating Aging and Longevity
ISBN: 9781402013690 / Angielski / Twarda / 333 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. After decades of systematic collection of data describing age-related changes in organisms, organs, tissues, cells and macromolecules, biogerontologists are now in a position to construct general principles of ageing and explore various possibilities of intervention using rational approaches. While not giving serious consideration to the claims made by charlatans, it cannot be ignored that several researchers are making genuine attempts to test and develop various means of intervention for the prevention and treatment of age-related diseases, for regaining the functional abilities and for...
After decades of systematic collection of data describing age-related changes in organisms, organs, tissues, cells and macromolecules, biogerontologis...
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One Hundred Years of Chromosome Research and What Remains to Be Learned
ISBN: 9781402014390 / Angielski / Twarda / 219 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. One Hundred Years of Chromosome Research: What Remains to be Learned, offers the reader a critical analysis of the observations and experiments that shaped the last 100 years of chromosome research, as well as the ideas which prevailed during this period. One Hundred Years of Chromosome Research: What Remains to be Learned, offers the reader a critical analysis of the observations a... |
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The War on Cancer: An Anatomy of Failure, a Blueprint for the Future
ISBN: 9781402036187 / Angielski / Twarda / 227 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The National Cancer Act of 1971 propelled the War on Cancer, mainly by tapping the vast resources of the Federal government to confront the growing cancer challenge. As a result, all cancer initiatives funded by Federal dollars were channeled through a restructured National Cancer Institute and some predicted the conquest of cancer by the nation s bicentennial. Yet, over the ensuing three decades progress in the clinical setting has been slow, and cancer remains a largely incurable disease. After reviewing the history of cancer and its impact on the population,... The National Cancer Act of 1971 propelled the War on Cancer, mainly by tapping the vast resources of the Federal government to co... |
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