Gene-Environment Interactions & Human Diseases
ISBN: 9781634836807 / Angielski / Twarda / 394 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
|
cena:
1236,38 zł |
Genetics of the Mouse
ISBN: 9783662510162 / Angielski / Miękka / 408 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book, written by experienced geneticists, covers topics ranging from the natural history of the mouse species, its handling and reproduction in the laboratory, and its classical genetics and cytogenetics, to modern issues including the analysis of the transcriptome, the parental imprinting and X-chromosome inactivation. The strategies for creating all sorts of mutations, either by genetic engineering or by using mutagens, are also reviewed and discussed in detail. Finally, a last chapter outlines the methodology used for the analysis of complex or quantitative traits. ... This book, written by experienced geneticists, covers topics ranging from the natural history of the mouse species, its handling and reproduction i... |
|
cena:
702,00 zł |
Systems Biology of RNA Binding Proteins
ISBN: 9781493954346 / Angielski / Miękka / 468 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. After transcription in the nucleus, RNA binding proteins (RBPs) recognize cis-regulatory RNA elements within pre-mRNA sequence to form mRNA-protein (mRNP) complexes. Similarly to DNA binding proteins such as transcription factors that regulate gene expression by binding to DNA elements in the promoters of genes, RBPs regulate the fate of target RNAs by interacting with specific sequences or RNA secondary structural features within the transcribed RNA molecule. The set of functional RNA elements recognized by RBPs within target RNAs and which control the temporal, functional and spatial... After transcription in the nucleus, RNA binding proteins (RBPs) recognize cis-regulatory RNA elements within pre-mRNA sequence to form mRNA-protein... |
|
cena:
585,00 zł |
Metabolomics: From Fundamentals to Clinical Applications
ISBN: 9783319476551 / Angielski / Twarda / 350 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data interpretation and applications in medicine. It is the first volume to cover metabolomics clinical applications while also emphasizing analytical and statistical features. Moreover, future trends and perspectives in clinical metabolomics are also presented.
For researches already experienced in metabolomics, the book will be useful as an updated definitive reference. For beginners in the field and graduate students, the book will provide... This book provides a comprehensive view of metabolomics, from the basic concepts, through sample preparation and analytical methodologies, to data int...
|
|
cena:
897,02 zł |
The Age of Genomes: Tales from the Front Lines of Genetic Medicine
ISBN: 9780807008775 / Angielski / Miękka / 244 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A leading geneticist explores what promises to be one of the most transformative advances in health and medicine in history Almost every week, another exciting headline appears about new advances in the field of genetics. Genetic testing is experiencing the kind of exponential growth once seen with the birth of the Internet, while the plummeting cost of DNA sequencing makes it increasingly accessible for individuals and families. Steven Lipkin and Jon Luoma posit that today's genomics is like the last century's nuclear physics: a powerful tool for good if used correctly, but...
A leading geneticist explores what promises to be one of the most transformative advances in health and medicine in history Almost every we...
|
|
cena:
87,72 zł |
Behavior Genetics of Psychopathology
ISBN: 9781493953004 / Angielski / Miękka / 344 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. As a dynamic, interdisciplinary field, behavior genetics and its evolution are being followed closely by scientists across the psychological and medical domains. The discoveries surrounding the human genome and the advancement in molecular genetic technologies have led to studies becoming increasingly sophisticated and yielding yet more conclusive and useful results. This is certainly the case in the area of child and adult psychopathology.
Behavior Genetics of Psychopathology summarizes the state of the field, examining the role of genes and environment as they... As a dynamic, interdisciplinary field, behavior genetics and its evolution are being followed closely by scientists across the psychological and me... |
|
cena:
389,98 zł |
Plant Epigenetics and Epigenomics: Methods and Protocols
ISBN: 9781493962297 / Angielski / Miękka / 245 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Many fundamental discoveries concerning epigenetics and the elucidation of mechanisms of epigenetic regulation have developed from studies performed in plants. In Plant Epigenetics and Epigenomics: Methods and Protocols, leading scientists in the epigenetics field describe comprehensive techniques that have been developed to understand the plant epigenetic landscape. These include recently developed methods and techniques for analysis of epigenetically regulated traits, such as flowering time, transposon activation, genomic imprinting and genome dosage effects. Written in the highly... Many fundamental discoveries concerning epigenetics and the elucidation of mechanisms of epigenetic regulation have developed from studies performe... |
|
cena:
409,49 zł |
Nucleic Acid Nanotechnology
ISBN: 9783662509371 / Angielski / Miękka / 339 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book surveys the intersection of nucleic acid research with nanotechnology, including advances in synthetic modifications, applications in bioengineering, nanoscale design, medicine, genetic analysis, chemistry, molecular biology and material science.
This book surveys the intersection of nucleic acid research with nanotechnology, including advances in synthetic modifications, applications in bioeng...
|
|
cena:
919,83 zł |
Epigenetics: Mechanisms & Clinical Perspectives
ISBN: 9781634844901 / Angielski / Twarda / 235 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
|
cena:
1079,28 zł |
Toxicology in the Middle Ages and Renaissance
ISBN: 9780128095546 / Angielski / Miękka / 192 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Toxicology in the Middle Ages and Renaissance provides an authoritative and fascinating exploration into the use of toxins and poisons in the Middle Ages and Renaissance. Part of the History of Toxicology and Environmental Health series, this volume is a follow-up, chronologically, to the first two volumes which explored toxicology in antiquity. The book approximately covers the 1100s through the 1600s, delving into different aspects of toxicology, such as the contributions of scientific scholars of the time, sensational poisoners and poisoning cases, as well as... Toxicology in the Middle Ages and Renaissance provides an authoritative and fascinating exploration into the use of toxins and poisons in th... |
|
cena:
151,97 zł |
Genotoxicity and DNA Repair: A Practical Approach
ISBN: 9781493948291 / Angielski / Miękka / 483 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Genotoxicity and DNA Repair: A Practical Approach provides a key reference for determining how to analyze the genotoxic activity of molecules or materials and, at the same time, serves as a useful tool for researchers in the Environmental Mutagenesis and DNA Repair fields. Focused on genotoxicity assays recommended by the "OECD guidelines for the testing of chemicals," this volume also covers other useful assays, such as some gene mutation assays, the comet assay in different species and applications, and the SMART assays of Drosophila. For all the assays, the book presents brief... Genotoxicity and DNA Repair: A Practical Approach provides a key reference for determining how to analyze the genotoxic activity of molecule... |
|
cena:
428,99 zł |
Statistical Analysis of Next Generation Sequencing Data
ISBN: 9783319379050 / Angielski / Miękka / 432 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Next Generation Sequencing (NGS) is the latest high throughput technology to revolutionize genomic research. NGS generates massive genomic datasets that play a key role in the big data phenomenon that surrounds us today. To extract signals from high-dimensional NGS data and make valid statistical inferences and predictions, novel data analytic and statistical techniques are needed. This book contains 20 chapters written by prominent statisticians working with NGS data. The topics range from basic preprocessing and analysis with NGS data to more complex genomic applications such as copy... Next Generation Sequencing (NGS) is the latest high throughput technology to revolutionize genomic research. NGS generates massive genomic datasets... |
|
cena:
545,99 zł |
Fusion Genes and Cancer
ISBN: 9789813200937 / Angielski / Twarda / 432 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Development of cancer, a dreadful disease of mankind, is a multi-stage process involving numerous molecular alterations at both genomic and proteomic levels. Immense research for the past several decades in the field of cancer identified many such mutations and their role in carcinogenesis. Concept of 'fusion genes' seeded way back in 20th century has now grown into a new field of cancer research. However, there is a lack of knowledge among scientists about these fusion genes and their importance in cancer, which can be mainly attributed to unavailability of a comprehensive book on this...
Development of cancer, a dreadful disease of mankind, is a multi-stage process involving numerous molecular alterations at both genomic and proteomic ...
|
|
cena:
684,09 zł |
Deriving Drug Discovery Value from Large-Scale Genetic Bioresources: Proceedings of a Workshop
ISBN: 9780309447782 / Angielski / Miękka / 114 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The process of discovering and developing a new drug or therapy is extremely costly and time consuming, and recently, it has been estimated that the creation of a new medicine costs on average more than $2 billion and takes 10 years to reach patients. The challenges associated with bringing new medicines to market have led many pharmaceutical companies to seek out innovative methods for streamlining their drug discovery research. One way to increase the odds of success for compounds in the drug development pipeline is to adopt genetically guided strategies for drug discovery, and... The process of discovering and developing a new drug or therapy is extremely costly and time consuming, and recently, it has been estimated that th... |
|
cena:
197,36 zł |
Cancer Biomarkers in Body Fluids: Biomarkers in Circulation
ISBN: 9783319483597 / Angielski / Twarda / 509 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As... This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in cir... |
|
cena:
780,00 zł |
Ligand Binding in the Transmembrane Region
ISBN: 9783639414929 / Angielski / Miękka / 204 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
|
cena:
306,48 zł |
Practical Genetic Counseling for the Laboratory
ISBN: 9780190604929 / Angielski / Miękka / 408 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An essential manual for the future of genetic counseling Genetic counselors possess the important set of skills necessary to face the unique challenges encountered within the laboratory. As the primary liaisons between genetic technologies and patient-facing clinicians, lab counselors must have equal competency in genetic testing protocols, interpretation, and communication of clinical recommendations. Practical Genetic Counseling for the Laboratory is the first book to codify the theory and practice of laboratory genetic counseling in an accessible and...
An essential manual for the future of genetic counseling Genetic counselors possess the important set of skills necessary to face...
|
|
cena:
361,55 zł |
Applied Neurogenomics
ISBN: 9781493948611 / Angielski / Miękka / 158 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This detailed volume reflects the considerable new developments that have taken place in the area of applied neurogenomics, particularly with the rapid progress in next generation sequencing. Beginning with an introduction to the technologies relevant to neurogenomics with an emphasis on next generation sequencing, the book also covers detailed methods relevant to the genomics of neurodegenerative diseases, particularly Alzheimer's disease and Huntington's disease, targeted sequencing of psychiatric disorders, as well as the role of genomics in the development of personalized neurology.... This detailed volume reflects the considerable new developments that have taken place in the area of applied neurogenomics, particularly with the r... |
|
cena:
370,48 zł |
Gene Therapy of Solid Cancers: Methods and Protocols
ISBN: 9781493955923 / Angielski / Miękka / 387 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
|
cena:
428,99 zł |
Movement Disorder Genetics
ISBN: 9783319358550 / Angielski / Miękka / 530 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book covers recent developments and possible pitfalls in the diagnosis of genetic movement disorders and related conditions. It is divided into three sections: technical and scientific aspects; clinical aspects with guidance towards work-up; and ethical and legal aspects of genetic testing in a clinical and research setting. The first section includes chapters on genetic analysis and counselling with critical discussion of potential problems when interpreting the results. Clinical chapters summarize genetic forms of movement disorders including parkinsonism, tics and dystonia... This book covers recent developments and possible pitfalls in the diagnosis of genetic movement disorders and related conditions. It is divided int... |
|
cena:
428,99 zł |