Kategoria BISAC: Medical >> Research

This book describes in 13 chapters mechanisms of P450 used to monooxygenate substrates via the NAD(P)H/O₂ pathway using its peroxidase and peroxygenase functions. P450 also utilizes peroxides, peracids, periodate and iodosobenzene to oxygenate substrates via the shunt pathway. Also described are mechanisms used in the oxidation of pharmaceuticals by CYP3A4; acyl- carbon cleavage by CYP17A1, CYP19A1 and CYP51A1; metabolism of tetrabromodiphenyl ethers and bile acids by CYP2B6 and CYP3A4; metabolism of ω-6 and ω-3 polyunsaturated fatty acids;...

This book brings together most up-to-date information on different aspects of brain aging and on the strategies for intervention and therapy of age-related brain disorders. It includes 18 chapters by leading researchers, and each chapter is a comprehensive and critical review of the topic in question, discusses the current scenario and focuses on future perspectives. The target readership is the undergraduate and graduate students in the universities, in medical and nursing colleges, along with the post-graduate researchers and practicing clinicians who would like to know about the latest...

This book is designed to be a long term career reference. The chapters present modern procedures. This is a how-to-book with a difference. These chapters:
- reveal the background information about working with salt loving organisms,
- are loaded with information about how experiments are conducted under high salt,
- provide information about analyses that work under these conditions and those that may not,
- present a wide range of details from laboratory designs to equipment used and even to simple anecdotal hints that can only come from experience.
Microbiological...

A practical guide to understanding and navigating the unique challenges faced by physicians and other professionals who wish to undertake research in the ED or other acute care setting.

Focusing on the hyper-acute and acute care environment and fulfilling two closely-related needs:

1) the need for even seasoned researchers to understand the specific logistics and issues of doing research in the ED; and 2) the need to educate clinically active physicians in research methodology.

This new text is not designed to be a complex, encyclopedic resource, but...

Based upon a workshop entitled The Small HSP World held in Quebec 2-5 October 2014.Twenty-five scientists provided chapters for the book.The chapters are from the best scientists currently working in this field. These colleagues include Arrigo, Benjamin, Buchner-Haslbeck-Weinkauf, Benndorf, Boelens, Carra, Chang, Currie, Ecroyd, Emanuelsson, Fu, Garrido, Golenhofen, Gusev, Kampinga, Lavoie, MacRae, Quinlan, Tanguay, Vierling, Vigh, Weeks and Wu. Briefly, the book starts with the structure of small heat shock proteins, moving to their functions and finishing with their involvement in...

In the informal language of letters to public officials, Efraim Racker argues in favor of basic research as the most effective path to the treatment of disease. He contends that knowledge of the fundamentals of biological and biochemical processes is essential if we are to gain an understanding of disease processes. He then shows how this understanding is necessary for a rational approach to the prevention and cure of disease.

Originally published in 1979.

The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously...

Osteoporosis Research - Animal Models is a reference book of the major animal models used in the study of Osteoporosis. Use of animal models provides important knowledge about pathological conditions that can eventually lead to the development of more effective clinical treatment of diseases in both humans and animals. This book is directed primarily toward endocrinologists, rheumatologists, geriatricians, gerontologists, bone biologists, investigators, research fellows, graduate students, and those working in osteoporosis research. This book is intended to serve as a basis for a...