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Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Compounds: Volume 27
ISBN: 9780120329274 / Angielski / Twarda / 519 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.
Conjugation reactions have long been associated with the detoxification of xenobiotics. Recent studies suggest that Phase II reactions are an important mechanism for the bioactivation of xenobiotics. This special volume of Advances in Pharmacology features a two-color dust jacket. Summarizes the most recent information on:
Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of dr...
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449,19 zł |
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Advances in Pharmacology: Volume 30
ISBN: 9780120329311 / Angielski / Twarda / 399 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.
Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of dr...
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449,19 zł |
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Toxicology of Organophosphate and Carbamate Compounds
ISBN: 9780120885237 / Angielski / Twarda / 763 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use... This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitu... |
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1402,65 zł |
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Organophosphates Chemistry, Fate, and Effects: Chemistry, Fate, and Effects
ISBN: 9780121673451 / Angielski / Twarda / 440 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity.
This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts ...
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449,19 zł |
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Fundamentals of Preparative and Nonlinear Chromatography
ISBN: 9780123705372 / Angielski / Twarda / 975 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The second edition of Fundamentals of Preparative and Nonlinear Chromatography is devoted to the fundamentals of a new process of purification or extraction of chemicals or proteins widely used in the pharmaceutical industry and in preparative chromatography. This process permits the preparation of extremely pure compounds satisfying the requests of the US Food and Drug Administration. The book describes the fundamentals of thermodynamics, mass transfer kinetics, and flow through porous media that are relevant to chromatography. It presents the models used in chromatography and their...
The second edition of Fundamentals of Preparative and Nonlinear Chromatography is devoted to the fundamentals of a new process of purification ...
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1374,56 zł |
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Primate Models of Children's Health and Developmental Disabilities
ISBN: 9780123737434 / Angielski / Twarda / 453 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The rate of neurodevelopmental disabilities, including autism, mental retardation, hearing loss and attention deficit hyperactivity disorder is rising in the United States. Although estimates of the prevalence of these disorders vary, figures from the CDC indicate that 4% of all school age children are developmentally disabled. During infancy, many important milestones in behavioral development are shared between human and nonhuman primates. Learning more about the causes of abnormal development in monkeys has provided important insights into the mechanisms underlying neurodevelopmental...
The rate of neurodevelopmental disabilities, including autism, mental retardation, hearing loss and attention deficit hyperactivity disorder is rising...
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363,04 zł |
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Loomis's Essentials of Toxicology
ISBN: 9780124556256 / Angielski / Twarda / 282 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Loomis's Essentials of Toxicology is an introductory text on the science of harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved; the general properties of chemicals and biologic systems as they influence the occurrence of detrimental biologic effects; the methods used to demonstrate these effects; and the basis for clinical diagnosis and therapy of harmful effects of chemicals on humans. Individual examples are used to demonstrate each of the principles under... Loomis's Essentials of Toxicology is an introductory text on the science of harmful biologic effects associated with exposures to chemicals ... |
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406,69 zł |
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Nicotine Safety and Toxicity
ISBN: 9780195114966 / Angielski / Twarda / 224 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Nicotine has been developed as a medication to assist smoking cessation, and is being considered as a possible drug for long-term maintenance of non-smoking. It is also undergoing evaluation as a possible treatment for several medical disorders, including ulcerative colitis, Alzheimer's disease, Parkinson's disease, Tourette's syndrome, attention deficit disorder, spasticity, and sleep apnea. Understanding its safety and toxicity is essential for drug developers, drug regulators, and clinicians making risk/benefit decisions about long-term nicotine therapy. Research on nicotine toxicity is...
Nicotine has been developed as a medication to assist smoking cessation, and is being considered as a possible drug for long-term maintenance of non-s...
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374,85 zł |
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Molecular Toxicology
ISBN: 9780195176209 / Angielski / Twarda / 608 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The science of toxicology has progressed considerably since Molecular Toxicology was first published in 1997. New advances in biochemical and molecular biological experimental techniques have helped researchers understand the precise effects of toxins and foreign compounds on living things at the molecular, cellular, and organismal levels. Breakthrough research has recently been completed illuminating the human genome and the role of enzymes in toxic biochemical reaction mechanisms. Toxicology now covers drug metabolism and design, carcinogenesis, programmed cell death, and DNA...
The science of toxicology has progressed considerably since Molecular Toxicology was first published in 1997. New advances in biochemical and...
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657,41 zł |
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Magic Mineral to Killer Dust: Turner & Newall and the Asbestos Hazard
ISBN: 9780198296904 / Angielski / Twarda / 336 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Asbestos was once known as the 'magic mineral' because of its ability to withstand flames. Yet since the 1970s, it has become a notorious an d feared 'killer dust' that is responsible for thousands of deaths and an epidemic that will continue for many years.
Asbestos was once known as the 'magic mineral' because of its ability to withstand flames. Yet since the 1970s, it has become a notorious an d feared ...
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952,25 zł |
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Toxic Plants: Proceedings of the 18th Annual Meeting of the Society for Economic Botany, Symposium on Toxic Plants, June 11-15, 1977
ISBN: 9780231046862 / Angielski / Twarda / 195 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The dependency of the human race on plants as renewable sources of many foodstuffs, drugs, textiles, fuel, and building materials in generally acknowledged. However, the harmful effects produced by certain plant constituents, which result in an increasing incidence of poisoning cases in the United States each year, are not so widely appreciated. This book is not intended to be a comprehensive treatise on all substances from plants that are lethal or otherwise injurious to humans or livestock. Instead, owing to tremendous recent advances in the understanding of the chemical nature of their...
The dependency of the human race on plants as renewable sources of many foodstuffs, drugs, textiles, fuel, and building materials in generally acknowl...
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643,77 zł |
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Nutritional and Toxicological Consequences of Food Processing
ISBN: 9780306438912 / Angielski / Twarda / 542 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A variety of processing methods are used to make foods edible; to pennit storage; to alter texture and flavor; to sterilize and pasteurize food; and to destroy microorganisms and other toxins. These methods include baking, broiling, cooking, freezing, frying, and roasting. Many such efforts have both beneficial and harmful effects. It is a paradox of nature that the processing of foods can improve nutrition, quality, safety, and taste, and yet occasionally lead to the formation of anti-nutritional and toxic compounds. These multifaceted consequences of food processing arise from molecular...
A variety of processing methods are used to make foods edible; to pennit storage; to alter texture and flavor; to sterilize and pasteurize food; and t...
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cena:
765,72 zł |
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Advances in Mercury Toxicology
ISBN: 9780306441165 / Angielski / Twarda / 490 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book is based on an international meeting organized by the University of Tokyo and the University of Rochester, and is published as one belonging to the series of Rochester International Conferences in Environmental Toxicity. The meeting on "Advances in Mercury Toxicology" was held at the University of Tokyo on August 1 to 3, 1990. The invited papers are published in this book along with an "Overview" chapter that was written by the editors at a meeting held at the University of Rochester on August 1 to 2, 1991. The purpose of the meeting was to assemble leading scientists to discuss...
This book is based on an international meeting organized by the University of Tokyo and the University of Rochester, and is published as one belonging...
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cena:
765,72 zł |
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Use of Biomarkers in Assessing Health and Environmental Impacts of Chemical Pollutants
ISBN: 9780306445392 / Angielski / Twarda / 286 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Biological markers (biomarkers) are useful tools for understanding the nature and extent of human exposure and risk from environmental toxicants. Biomarkers are classified into three basic categories: exposure, effect, or susceptibility. A marker of exposure is the product of the interaction between a target cell or molecule and a foreign substance (NAS, 1989). These markers can be used to determine the biologically effective dose necessary to elicit a particular physiological change in an organism. A marker of effect is a biochemical or physiological change in an organism that can predict...
Biological markers (biomarkers) are useful tools for understanding the nature and extent of human exposure and risk from environmental toxicants. Biom...
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cena:
574,29 zł |
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Dioxins and Health
ISBN: 9780306447853 / Angielski / Twarda / 710 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book originated in a series of cross-disciplinary conversations in the years 1984-1990 between the editor, who is a physician-researcher involved in clinical and laboratory research, and a dioxin toxicologist. During the years in which the conversations took place, an extraordinary amount of new scientific literature was published related to dioxins, defined for purposes of this text as the chlorinated dibenzo-p-dioxins, dibenzofurans, polychlorinated biphe nyls (PCB's) and other compounds that are structurally and toxicologically similar to 2,3,7,8-tetrachlorodibenzo-p-dioxin...
This book originated in a series of cross-disciplinary conversations in the years 1984-1990 between the editor, who is a physician-researcher involved...
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cena:
765,72 zł |
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Biological Reactive Intermediates V: Basic Mechanistic Research in Toxicology and Human Risk Assessment
ISBN: 9780306451973 / Angielski / Twarda / 462 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Much of organic chemistry is based on the ability of suitably structured chemicals to bind together through the formation of covalent bonds. Biochemistry is replete with exam- ples of enzymatically catalyzed reactions in which normal body constituents can be linked through covalent bonds during the process of intermediary metabolism. The finding that xenobiotic chemicals that enter the body from the environment, are metabolized to highly reactive species, and then covalently react with cellular macromolecules to induce toxic and carcinogenic effects was an observation that spawned the...
Much of organic chemistry is based on the ability of suitably structured chemicals to bind together through the formation of covalent bonds. Biochemis...
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cena:
765,72 zł |
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Fumonisins in Food
ISBN: 9780306452161 / Angielski / Twarda / 399 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The contents of this book are the proceedings of the ACS symposium, "Fumonisins in Food," which was held April 4-6, 1995, at the American Chemical Society National Meeting in Anaheim, CA. This symposi"Qm, which was international in scope, brought together researchers from diverse backgrounds in academia, government, and industry. Thirty-three speakers discussed topics ranging from the analysis offumonisins to toxicology and regulatory aspects. The fumonisins became the spotlight of mycotoxin research in 1988, when re- searchers at the South African Medical Research Council isolated and...
The contents of this book are the proceedings of the ACS symposium, "Fumonisins in Food," which was held April 4-6, 1995, at the American Chemical Soc...
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574,29 zł |
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Biological Reactive Intermediates VI: Chemical and Biological Mechanisms in Susceptibility to and Prevention of Environmental Diseases
ISBN: 9780306466595 / Angielski / Twarda / 728 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolites, that is, toxic and carcinogenic effects, which have been the basis of all five earlier volumes in this series. In particular, this volume devotes sections to structure-activity relationships, advances in the understanding of the chemistry of reactive metabolites, and the generation and activity of reactive oxygen species with special emphasis on nitric oxide. There are also segments on DNA damage by reactive metabolites and DNA repair,...
This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolit...
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cena:
765,72 zł |
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Reviews of Environmental Contamination and Toxicology 188
ISBN: 9780387319117 / Angielski / Twarda / 225 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications. Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant ... |
cena:
382,84 zł |
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Reviews of Environmental Contamination and Toxicology 189
ISBN: 9780387353678 / Angielski / Twarda / 185 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications. Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant ... |
cena:
382,84 zł |
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