Kategoria BISAC: Medical >> Toxicology

This book provides an overview of current available biomarkers and human biomonitoring programs in environmental health, addressing current concerns regarding adverse health effects from environmental exposures.

In May of 2011, Western Europe experienced a severe outbreak of Shiga toxin (Stx)-producing E. coli (STEC) that culminated in more than 3200 cases and 39 deaths. While Stx is not the only virulence factor associated with STEC, it is certainly the primary determinant associated with the onset of hemolytic uremic syndrome (HUS). At the present time, there are no clinically approved measures to neutralize Stx in individuals suffering from STEC infection. Nor are there any preventatives or therapeutics for ricin toxin. Although incidents of ricin exposure are largely unheard of,...

Developing better therapies for neurological conditions such as Parkinson s and Alzheimer s diseases remains an enduring problem for 21^st century medicine. The testing of novel therapies will continue to require a robust experimental animal model. The marmoset is an ideal animal model for modern neurological research because of the species convenient body size, ease of handling, and the fundamental similarity of its neuroanatomy to the human brain.

The Stereotaxic and Chemoarchitectural Atlas of the Brain of the Common Marmoset (Callithrix...

Up to 200 million people in 70 countries are at risk from drinking water contaminated with arsenic, which is a major cause of chronic debilitating illnesses and fatal cancers. Until recently little was known about the mobility of arsenic, and how redox transformations determined its movement into or out of water supplies. Although human activities contribute to the release of arsenic from minerals, it is now clear that bacteria are responsible for most of the redox transformation of arsenic in the environment. Bacterial oxidation of arsenite (to the less mobile arsenate) has been known...

Modern technology using state-of-the-art equipment can now identify almost any toxin relevant to a legal issue. Techniques include gas chromatography, mass spectrometry, high-pressure liquid chromatography, and the combination of these methods. Forensic Toxicology: Medico-legal Case Studies demonstrates how the science of forensic toxicology acts as a bridge between medicine and law. Tracking the progression of toxicology findings from the laboratory to the courtroom, it prepares practicing toxicologists to write reports and testify at depositions and in court.

Ecotoxicology Modeling is a comprehensive and well-documented text providing a collection of computational methods to the ecotoxicologists primarily interested in the study of the adverse effects of chemicals, their mechanisms of action and/or their environmental fate and behavior. Avoiding mathematical jargon, the book presents numerous case studies to enable the reader to understand the interest but also the limitations of linear and nonlinear models in ecotoxicology.

Written by an international team of scientists, Ecotoxicology Modeling is of...