Farnesyltransferase Inhibitors in Cancer Therapy
ISBN: 9781468496062 / Angielski / Miękka / 280 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cutting-edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farensyltransferase inhibitors (FTIs); geranylgeranyltransferase inhibitors (GGTIs) are also discussed as potential anticancer drugs. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other cytotoxic agents, such as gemcitabine, cisplatin, and taxanes. Illuminating and richly detailed, Farnesyltransferase Inhibitors in Cancer Therapy...
Cutting-edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farensyltransferase inhibitors (FTIs)...
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cena:
585,00 zł |
Functional Molecular Silicon Compounds I: Regular Oxidation States
ISBN: 9783319036199 / Angielski / Twarda / 233 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecular electronics, designed molecular solids, surfaces, metal clusters and supramolecular structures. Physical and spectroscopic techniques used to determine, examine and model structures fall within the...
The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the seri...
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cena:
780,00 zł |
Experiments in Pharmaceutical Chemistry
ISBN: 9781482225082 / Angielski / Miękka / 160 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Written by an author with more than 40 years of teaching experience in the field, Experiments in Pharmaceutical Chemistry, Second Edition responds to a critical classroom need for material on directed laboratory investigations in biological and pharmaceutical chemistry. This new edition supplies 75 experiments, expanding the range of topics to 22 major areas of pharmaceutical chemistry. These include biochemical groups, botanical classes important to pharmacy, and major drug classifications:
Written by an author with more than 40 years of teaching experience in the field, Experiments in Pharmaceutical Chemistry, Second Edition re... |
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354,66 zł |
Saponins Used in Traditional and Modern Medicine
ISBN: 9781489913692 / Angielski / Miękka / 606 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. ''A wealth of information...these two volumes will be immensely valuable to anyone having to deal with this difficult group of compounds.'' ---Biochemical Systematics and Ecology, from a review of Saponins Used in Traditional and Modern Medicine and Saponins Used in Food and Agriculture
''A wealth of information...these two volumes will be immensely valuable to anyone having to deal with this difficult group of compounds.'' ---Biochem...
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cena:
780,00 zł |
Phytochemistry of Medicinal Plants
ISBN: 9781489917805 / Angielski / Miękka / 364 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Phytochemicals from medicinal plants are receiving ever greater attention in the scientific literature, in medicine, and in the world economy in general. For example, the global value of plant-derived pharmaceuticals will reach $500 billion in the year 2000 in the OECD countries. In the developing countries, over-the-counter remedies and "ethical phytomedicines," which are standardized toxicologically and clinically defined crude drugs, are seen as a promising low- cost alternatives in primary health care. The field also has benefited greatly in recent years from the interaction of the study...
Phytochemicals from medicinal plants are receiving ever greater attention in the scientific literature, in medicine, and in the world economy in gener...
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cena:
780,00 zł |
Small Molecule -- Protein Interactions
ISBN: 9783662053164 / Angielski / Miękka / 228 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Based on the international workshop on 'Small Molecule - Protein Interactions' held in Berlin, April 24-26, 2002, researchers from industry and academic laboratories describe novel and efficient ways selecting promising new drug targets and developing small molecule inhibitors against them. The structure of the book corresponds to the different aspects of the drug discovery process. All chapters are written by leading experts in the field, who present and discuss the most recent state-of-the-art tools and techniques for the development of novel drugs. The value of the book lies in surveying...
Based on the international workshop on 'Small Molecule - Protein Interactions' held in Berlin, April 24-26, 2002, researchers from industry and academ...
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cena:
389,98 zł |
From Morphological Imaging to Molecular Targeting: Implications to Preclinical Development
ISBN: 9783662073124 / Angielski / Miękka / 196 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Because of the current progress in molecular medicine (genomics, proteomics), a plethora of new and often human-specific targets are being identified. These targets often play a significant role in the pathogenesis of diseases, and identifying them offers the potential for early diagnosis and intervention. An early in vivo validation of specific ligands binding to these targets in humans is needed to as sess their potential for targeted imaging and radiotherapy. Further- VI Preface more, such validation studies may allow for a better understanding of the molecular processes underlying...
Because of the current progress in molecular medicine (genomics, proteomics), a plethora of new and often human-specific targets are being identified....
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cena:
585,00 zł |
Galenics of Insulin: The Physico-Chemical and Pharmaceutical Aspects of Insulin and Insulin Preparations
ISBN: 9783662025284 / Angielski / Miękka / 103 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Galenical pharmacy or galenics is the science dealing with the pro duction of drug substances from raw materials, the purity of such substances, their formulation into pharmaceutical preparations with the desired effects and safety in use, and the quality control, stability and storage of the preparations. The field has taken its name from the Greek physician Galen (131-201 A.D.), who had a profound influence on medicine for many centuries because he collected and systematized the medicinal knowledge of his time. The discovery of insulin is attributed to Banting and Best who, in 1921,...
Galenical pharmacy or galenics is the science dealing with the pro duction of drug substances from raw materials, the purity of such substances, their...
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cena:
194,97 zł |
Biologically Active Substances of Protozoa
ISBN: 9789401037877 / Angielski / Miękka / 112 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book outlines one of the vast and fruitful fields in protozoan microbiology and formulates the principles of obtaining biologically active substances from cultures of Protozoa. The correlation between composition of selected flagellates' cell components (polyunsaturated fatty acids, membrane surface glycophospolipids, intercellular polysaccharide, beta-1, 3-glycan) and their biological effects in experimental animals, is the main topic of the book. As the book's content shows, the Protozoa are gradually acquiring their place among traditional producers of biologically active substances....
This book outlines one of the vast and fruitful fields in protozoan microbiology and formulates the principles of obtaining biologically active substa...
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cena:
389,98 zł |
Animal Cell Technology: From Vaccines to Genetic Medicine
ISBN: 9789401062732 / Angielski / Miękka / 816 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Animal cell technology has undergone a rapid transformation over the last decade from a research tool and highly specialised technology to a central resource for innovation in pharmaceutical research and development. These proceedings of the 14th Meeting of the European Society for Animal Cell Technology (Vilamoura, Portugal, May 1996) bring up to date the historical perspective of animal cell technology for the benefit of society, From Vaccines to Genetic Medicine', and will charter this vital technology for the years to come.
Strong contributions are grouped in the traditional ESACT... Animal cell technology has undergone a rapid transformation over the last decade from a research tool and highly specialised technology to a central r...
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cena:
1170,03 zł |
Fortschritte Der Chemie Organischer Naturstoffe: Progress in the Chemistry of Organic Natural Products
ISBN: 9783709132265 / Angielski / Miękka / 680 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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cena:
780,00 zł |
Progress in the Chemistry of Organic Natural Products
ISBN: 9783709171998 / Angielski / Miękka / 267 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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cena:
389,98 zł |
Progress in the Chemistry of Organic Natural Products Vol. 94
ISBN: 9783709111178 / Angielski / Miękka / 254 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The three reviews cover the advances in the chemistry and biology of withanolides over the last 16 years, review the chemistry and biology of the rocaglamide-type derivatives and related compounds, with emphasis on their structural diversity, biosynthesis, pharmacological significance and total synthesis, and summarize the extensive chemistry and biology studies on a natural product, which have resulted in a novel therapy approved worldwide.
The three reviews cover the advances in the chemistry and biology of withanolides over the last 16 years, review the chemistry and biology of the roca...
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cena:
780,00 zł |
Functional Molecular Silicon Compounds II: Low Oxidation States
ISBN: 9783319037332 / Angielski / Twarda / 232 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecular electronics, designed molecular solids, surfaces, metal clusters and supramolecular structures. Physical and spectroscopic techniques used to determine, examine and model structures fall within the...
The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the seri...
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cena:
780,00 zł |
Protein Pharmacokinetics and Metabolism
ISBN: 9781489923318 / Angielski / Miękka / 276 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Investigation of the pharmacokinetics and metabolism of human proteins has escalated over the last two decades because of the use of recombinant human proteins as therapeutic agents. In addition, the development and improvement of analytical techniques enabling the detection of minute quantities of proteins in biological matrices have aided this process. In assembling this volume, we sought to provide a state-of-the-art as- sessment of the pharmacokinetics and metabolism of protein therapeutics through complete reviews of selected examples. A comprehensive review of all protein therapeutics...
Investigation of the pharmacokinetics and metabolism of human proteins has escalated over the last two decades because of the use of recombinant human...
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cena:
585,00 zł |
Mammalian Cell Cultures for Biologics Manufacturing
ISBN: 9783642540493 / Angielski / Twarda / 259 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.
Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series als...
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cena:
1482,04 zł |
The Adrenocortical Hormones: Their Origin · Chemistry Physiology and Pharmacology
ISBN: 9783662131343 / Angielski / Miękka / 214 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. 2 Vol. 3: Hormones, Psychology and Behavior (1952). A range of interests was covered in respect to the influence of glucocorticoids on behavioral responses, as well as to the glucocorticoid status in various behavioral states and disorders. Vol. 4: Anterior Pituitary Secretion and Hormonal Influence in Water Metab- olism (1952). Book II of this volume contains considerable detail about the various relationships of the glucocorticoids to other hormones with respect to their influence on water and electrolyte excretion. Vol. 5: Bioassay of Anterior Pituitary and Adrenal Cortical Hormones...
2 Vol. 3: Hormones, Psychology and Behavior (1952). A range of interests was covered in respect to the influence of glucocorticoids on behavioral resp...
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cena:
194,97 zł |
Erzeugung von Krankheitszuständen durch das Experiment: Tumoren I
ISBN: 9783662225677 / Niemiecki / Miękka / 564 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. ingezuchteten Tiermaterial entsprechenden Transplantationsgeschwulste lassen sich ebenfalls durch chemische Cancerogene, z. B. Kohlenwasserstoffe, Azo farbstoffe, Stilbene, Nitrosamine usw., in der gewunschten histologischen Form am leichtesten erzeugen. In den nachfolgenden Abschnitten sollen mit dieser rein praktischen Ziel setzung, namlich der Schaffung von guten adaquaten Modellen fur den mensch lichen Krebs fur die verschiedensten experimentellen Arbeitsrichtungen, in sonderheit die Chemotherapie, mannigfaltige Verfahren der chemischen Krebs induktion bei verschiedenen Tierarten und in...
ingezuchteten Tiermaterial entsprechenden Transplantationsgeschwulste lassen sich ebenfalls durch chemische Cancerogene, z. B. Kohlenwasserstoffe, Azo...
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cena:
400,90 zł |
Erzeugung Von Krankheitszuständen Durch Das Experiment: Tumoren II
ISBN: 9783662268018 / Niemiecki / Miękka / 234 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. (1952), HoRNING (1956), DoNTENWILL und EDER (1959)]. Wir sahen dabei fast immer basophile Adenome mit z. T. hochgradiger Zellpolymorphie und typischen Crooke-Zellen rpit Vacuolen (Abb. 3a u. b). Die Adenome fiihrten hiiufig zu De- formierungen der Schiidelbasis. Bei diesen Adenomen konnten keine Veriinderun- gen an den endokrinen Driisen oder endokrin gesteuerten Organen nachgewiesen werden, die auf eine Mehrsekretion der vergr6Berten Hypophyse hindeuten. 1. Spezielle Hypophysenadenome Wahrend bei den bisher angefiihrten Adenomen oder Hyperplasien keine be- stimmte Differenzierung nach ihrer...
(1952), HoRNING (1956), DoNTENWILL und EDER (1959)]. Wir sahen dabei fast immer basophile Adenome mit z. T. hochgradiger Zellpolymorphie und typischen...
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cena:
200,43 zł |
Biotechnology in Medical Sciences
ISBN: 9781482223675 / Angielski / Twarda / 496 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. As the field of medical biotechnology grows with new products and discoveries, so does the need for a holistic view of biotechnology in medicine. Biotechnology in Medical Sciences fulfills that need by delivering a detailed overview of medical biotechnology as it relates to human diseases and epidemiology, bacteriology and antibiotics, virology and vaccines, immunology and monoclonal antibodies, recombinant DNA technology and therapeutic proteins, stem cell technology, tissue engineering, molecular diagnostics and forensic science, gene therapy, synthetic biology and nanomedicine,... As the field of medical biotechnology grows with new products and discoveries, so does the need for a holistic view of biotechnology in medicine. <... |
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cena:
785,43 zł |