Kategoria BISAC: Medical >> Oncology - General

This classic work by a physician survivor has helped thousands of cancer patients and their families. Now updated with the latest information on diagnosis and treatment, it provides expanded information and advice that helps Healthy Survivors through the accompanying challenges. New to this edition is the Harpham's Decision Tool, a unique chart for deciding on your best course of treatment. A succinct and empowering book for those diagnosed with any type of cancer, Diagnosis: Cancer covers all the important topics that will help you through these months of turmoil, including information on...

This book is intended as a text for a first course on creating and analyzing computer simulation models of biological systems. The expected audience for this book are students wishing to use dynamic models to interpret real data mueh as they would use standard statistical techniques. It is meant to provide both the essential principles as well as the details and equa- tions applicable to a few particular systems and subdisciplines. Biological systems, however, encompass a vast, diverse array of topics and problems. This book discusses only a select number of these that I have found to be...

Recently there have been many advances in the understanding of the genetic basis of development and regular breakthroughs are being made in the field of tumour cell targeting. Both these areas of research are coming together in terms of their perception of programmed cell death.

The normally functioning cell has controls which prevent it proliferating and invading regions of the body from which it is normally excluded. Under certain conditions, the normal rules breakdown and cell proliferation and migration, or metastasis, leads to the formation of tumours. The metastatic behaviour of malignant tumour cells is responsible for the majority of cancer deaths. This book deals with the behaviour and biochemistry of errant cells, a subject that is at the forefront of current reserch in cellular and molecular biology, providing general and specialized information on cell...

Recent advances in immunology and molecular biology have resulted in new therapeutic approaches being generated and implemented in cancer clinics. The discovery of new antigens, mechanisms of antigen presentation, and interplay of cells involved in anti-tumor immunity have made the clinical control of some cancers more plausible than previously thought. An invaluable source for clinicians, researchers, and students, Tumor Immunology presents an introductory overview of the immunology of cancer including therapeutic approaches. Topics covered include the immune recognition of cancer-tumor...

Recent progress in fundamental tumor immunology has led to immunotherapy trials in patients with solid tumors and hematological malignancies. In the past, immunotherapy approaches were primarily based on enhancement of tumor immunity with cytokines and adjuvant therapy, without knowledge of relevant tumor antigens. The discovery of tumor antigens capable of eliciting immune responses has now resulted in the development of antigen-specific immunotherapy strategies. Vaccination with defined peptide epitopes, purified proteins, cell components, and whole cells expressing defined tumor antigens...

Bringing together some of the most progressive and important thinking in the area, key features of the book include insightful descriptions of models of integrative care, and of the perspectives and practices of alternative systems of healing discussions of the transformational experience that the cancer care process may bring for physicians and patients * clear summaries of research, business, clinical and legal considerations reviews of the contributions of CAM therapies to preventive, supportive, antineoplastic, palliative and end-of-life care comprehensive references regarding the...

Medical oncologists and other healthcare professionals in the field of oncology will welcome this concise guide on the new and rapidly evolving field of cellular oncology and targeted therapies. This handbook presents the principles of cell biology and the role of the immune system; the etiology of carcinogenesis; differenct cellular pathways, and their implications for drug development in oncology. Using state-of-the-art ecidence-based literature references and reviews, with illustrations as necessary, the authors present on overvieew that is both reliable and easily understood.

Cytogenetics, fluorescence in situ hybridization (FISH) and molecular tests, especially polymerase chain reaction (PCR), play an important role in the management of patients with hematologic malignancies by helping to establish the diagnosis, as well as predict prognosis, response to treatment and disease progression. Chromosomal and molecular abnormalities provide the most reliable criteria for classification of hematopoietic tumors and often comprise the basis for targeted therapy.

Cytogenetics, FISH and Molecular Testing in Hematologic Malignancies, provides a...

Prostate cancer is treated in a number of different ways, depending on a host of different factors, ranging from the severity of the cancer, the health of the patient, their age, and their own personal choice of treatment. Whether the choice is open or laparoscopic surgery, laser treatment or cryoablation, ultimately, the options open to the urologic surgeon today are modelled and defined specific to the patient's individual needs.

Treatment Methods for Early and Advanced Prostate Cancer focusses on the "how to treat" scenario faced by urologic surgeons treating all stages...

Prognostic Factors in Cancer, Third Edition examines the prognostic factors associated with each cancer site and provides insight into potential treatments and therapies. The text is an extension of the International Union Against Cancer's (UICC) seminal work, the TNM Classification of Malignant Tumours, and integrates the current focus on prognostics in cancer.

This Third Edition reflects the advances in cancer diagnosis and treatment planning made in recent years. The first part of the book offers a complete update on the science of cancer prognosis while the second part...

Advances in research and the treatment of cancer mean that more patients and their carers are asking healthcare professionals about the latest treatments and how they may be of benefit. It is essential that staff working with cancer patients understand fully how these new treatments work in order to disseminate timely and appropriate information to patients.

The application of biology to the delivery of cancer care is playing an ever-increasing role in the management of these diseases. The Biology of Cancer: Second Edition provides details of the most recent developments in cancer...

Edited by the winner of the 2008 Mike Price Fellowship

The Cancer Clock is a comprehensive overview of cancer as a single topic and provides an all-encompassing account of the key aspects related to the disease from its causes and initial diagnosis through to treatment and care and the different support mechanisms available. Carefully divided into three key parts, the first part of the book focuses on the genesis of the disease through environmental, lifestyle and socioeconomic factors. The second part moves on to consider early disease, disease development, diagnosis,...

Human health risk assessment involves the measuring of risk of exposure to disease, with a view to improving disease prevention. Mathematical, biological, statistical, and computational methods play a key role in exposure assessment, hazard assessment and identification, and dose-response modelling.

Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment is a comprehensive text that accounts for the wealth of new biological data as well as new biological, toxicological, and medical approaches adopted in risk assessment. It provides an authoritative...

A guide for health care professionals in the utilization of genetics in their management of patients at risk for, or already by, common cancers. Critical concepts in epidemiology and related population sciences are introduced to allow an integrated approach to the individual patient or family. The book also provides a framework for counselling patients, families and colleagues about the availability, benefits, and limitations of the new technologies for genetic risk assessment.

Heterocyclic amines (HCAs) are organic compounds comprising of carbon, hydrogen, and nitrogen in a ring structure. HCAs are believed to be cancer inducing, and are naturally-occurring compounds to which we are exposed to everyday.

This important new reference book on human cancer provides a global picture of the epidemiology of cancer and its environmental causes. By summarising on a cancer-by-cancer basis geographical, environmental and ethical factors, the volume collates a wealth of information which, taken together, provides valuable insights into the causes of cancer and scope for its elimination and control. The contents include: (1) general epidemiological methods; (2) a review of known or suspected causes; (3) a detailed review of specific cancers; (4) a brief review of legal and ethical implications. The...

The clinical applications of human gene therapy have been particularly fruitful in oncology, and in the past two decades there has been explosive growth in understanding of the genetic lesions leading to neoplasia. This volume in the series Cancer: Clinical Science in Practice reviews progress in the basic and clinical science of gene therapy in oncology, and looks toward future developments. It considers what has worked and what has not in the fast-evolving field of gene therapy, drawing on laboratory studies and clinical trials, including the ground-breaking work of the contributors...

The clinical applications of human gene therapy have been particularly fruitful in oncology, and in the past two decades there has been explosive growth in understanding of the genetic lesions leading to neoplasia. This volume in the series Cancer: Clinical Science in Practice reviews progress in the basic and clinical science of gene therapy in oncology, and looks toward future developments. It considers what has worked and what has not in the fast-evolving field of gene therapy, drawing on laboratory studies and clinical trials, including the ground-breaking work of the contributors...

Drug resistance in cancer, whereby a portion of cancer cells evades chemotherapy, poses a profound and continuing challenge for the effective treatment of cancer. The principles underlying the biological mechanisms behind this phenomenon are clearly explained in this volume. A deeper understanding of drug resistance requires a quantitative appreciation of the dynamic forces that shape tumor growth, including spontaneous mutation and selection processes. The authors seek to explain and to simplify these complex mechanisms, and to place them in a clinical context. Clearly explained mathematical...