Kategoria BISAC: Medical >> Neuroscience

Mechanisms of neural plasticity enable the encoding and memorization of information based on sensory inputs and can be harnessed to partially restore function after CNS assault such as stroke or head trauma. In the present book, experts from the field of visual system plasticity describe and evaluate the evidence for neural mechanisms proposed to underlie CNS plasticity in the major divisions of the brain dedicated to visual processing, the retina, sub-cortical structures and cortex. We present studies from a wide variety of disciplines that range from molecular biology to neurophysiology...

The first two editions of this title had a tremendous impact in neuroscience. Between the Second edition in 1989 and today, there has been an explosion of information in the field, including advances in molecular techniques, such as genomics and proteomics, which have become increasing important in neuroscience. A renaissance in fluorescence has occurred, driven by the development of new probes, new microscopes, live imagers, and computer processing. The introduction of new markers has enormously stimulated the field, moving it from tissue culture to neurophysiology to functional MRI...

N-acetylaspartate, or NAA, is the acetylated form of the amino acid aspartate, and it is present exclusively in the nervous system. Indeed, NAA is one of the most highly concentrated chemicals found in the brain of humans and animals, and yet the functions served by this brain-specific metabolite remain elusive, and controversial. Despite the uncertainties surrounding the functions of NAA in the development and operation of the nervous system, this molecule has attracted the attention of researchers and clinicians for two distinct reasons.

First, the acetyl proton on NAA gives off...

This volume is a collection of a variety of brain proteins and peptides whose structures and functions are relatively well known. Each chapter provides a succinct and up-to-date summary of a protein or peptide as well as a review of the individual's contributions to the field. The volume explores the progress that has been made in the field over the past few years and provides insight into the field today.

Stroke is a global health problem affecting approximately 15 million people annually in the world and about 700,000 in the United States. It is the third leading cause of death and the most common cause of disability in most developed countries.

Acute Ischemic Injury and Repair in the Nervous System is intended to provide the most up-to-date knowledge of the mechanisms of neuronal death and repair after stroke. It is our belief that this volume of the Handbook of Neurochemistry and Molecular Neurobiology provides an excellent review of the tremendous advances of the past decades in...

Development & Plasticity in Sensory Thalamus & Cortex is based on a 2-day symposium offered for the first time at SFN 2003. The symposium focused on the latest findings and ideas, focusing on visual and somatosensory thalamus and neocortex in rodents and carnivores and functional imaging studies in developing and aging human neocortex, as well as plastic changes after spinal cord injury. This volume will cover recent advances in understanding sensory thalamic and cortical function, organization, and plasticity. Chapters will cover a broad range of approaches from single cell recordings to...

A major issue of modern neurobiology is to understand how neurons extend their neurites to form a functional network. While a large amount of information is available on the extracellular mechanisms driving neuritogenesis, the study of the intricate molecular machinery underlying the intracellular mechanisms has only recently been addressed. The purpose of this book is to present novel, distinct, but highly related aspects of the intracellular mechanisms required for the formation of a functional neurite, which include cytoskeletal organization, membrane traffic, and signal transduction....

This book provides a compilation of the most up-to-date literature on the topic of immediate early genes (IEGs). It reviews and details experiments and theories that challenge the reader to expand their view on how IEG research is currently being used to advance our understanding of static and active brain circuits. In addition, the book explores roles of IEGs in clinical neuropathology.

Present-day behavioral and cognitive neuroscience is based on the idea that the conventional philosophical theory of the mind provides a reliable guide to the functional organization of the brain. Consequently, much effort has been expended in a search for the neural basis of such psychological categories as memory, attention, emotion, motivation, and perception. This book argues that (a) conventional psychological concepts originate from the philosophical speculations of ancient Greek philosophers, especially Plato and Aristotle; (b) there is serious doubt that these ancient philosophical...

This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.

Neural Crest Induction and Differentiation, written by an international panel of recognized leaders in the field, discusses all aspects of modern neural crest biology from its evolutionary significance, to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function. Each chapter provides an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance.

This volume provides a comprehensive description of phospholipid metabolism in brain, activities of phospholipases A₂, and their involvement in neurological disorders. The purpose of this book is to present readers with cutting edge information in a lively manner that is useful not only to student and teachers but also to researchers and physicians.

Abl Family Kinases in Development and Disease provides an overview of the functions of Abl family kinases in Development and Disease. This new title discusses the biochemical, genetic, and cell biological data that elucidate the cellular roles for these kinases in these processes.

This text provides an overview of the processes of brain death, exploring the concepts and historical approach of human death, clinical examinations of brain-dead patients, ancillary tests in coma and brain death, bioethical discussions of brain death and its relationship with some consciousness disturbances, and the legal considerations of human death. Unlike other, narrow-focus reference this book encompasses a wide spectrum of issues including medical, legal, bioethical and historical aspects.