Over the last decade, the considerable progress made in biochemistry, molecular biology, genetics and neuropharmacology has revealed some ofthe intimate mechanisms ofthe neurodegenerative disorders. There is increasing evidence linking genetic defects affecting mitochondria to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease and some other neurological disorders. Advances in knowledge are fueled through improved animal models that use mitochondrial toxins, excitotoxins, and transgenic animals. Therapeutic studies in these models have strengthened...
Over the last decade, the considerable progress made in biochemistry, molecular biology, genetics and neuropharmacology has revealed some ofthe intima...
Stroke is a global health problem affecting approximately 15 million people annually in the world and about 700,000 in the United States. It is the third leading cause of death and the most common cause of disability in most developed countries.
Acute Ischemic Injury and Repair in the Nervous System is intended to provide the most up-to-date knowledge of the mechanisms of neuronal death and repair after stroke. It is our belief that this volume of the Handbook of Neurochemistry and Molecular Neurobiology provides an excellent review of the tremendous advances of the past decades in...
Stroke is a global health problem affecting approximately 15 million people annually in the world and about 700,000 in the United States. It is the...
This volume is concerned with the enzymes of the nervous system. Cerebral enzymes form the basis of the functional brain. They are needed for the control of the energetics of the nervous system, whether it be their release or their direction; for the elaboration of transmitters and for their destruction; for the synthesis, transport, and breakdown of all metabolites of the nervous system. They are indispensable for the control of the multitude of factors that govern our thinking and our behavior. They make it possible for us to comprehend what is taking place around us and perhaps to...
This volume is concerned with the enzymes of the nervous system. Cerebral enzymes form the basis of the functional brain. They are needed for the cont...
Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects for which experimental results are difficult to interpret. The breakdown part of protein turnover in vivo, particularly in nervous tissue, was such a subject in the past - it was difficult to measure and difficult to explore the mechanisms involved. For factors that influence protein metabolism, it was thought that protein content, function, and distribution are controlled only by the synthetic mechanisms that can supply the needed specificity and...
Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects fo...
Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects for which experimental results are difficult to interpret. The breakdown part of protein turnover in vivo, particularly in nervous tissue, was such a subject in the past - it was difficult to measure and difficult to explore the mechanisms involved. For factors that influence protein metabolism, it was thought that protein content, function, and distribution are controlled only by the synthetic mechanisms that can supply the needed specificity and...
Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects fo...
