This volume is concerned with the enzymes of the nervous system. Cerebral enzymes form the basis of the functional brain. They are needed for the control of the energetics of the nervous system, whether it be their release or their direction; for the elaboration of transmitters and for their destruction; for the synthesis, transport, and breakdown of all metabolites of the nervous system. They are indispensable for the control of the multitude of factors that govern our thinking and our behavior. They make it possible for us to comprehend what is taking place around us and perhaps to...
This volume is concerned with the enzymes of the nervous system. Cerebral enzymes form the basis of the functional brain. They are needed for the cont...
Life, either as we think of it in the abstract in its highest sense, or life, as we think of it in terms of a compact living organism, is obviously the result of complex interaction of all of the components of the organism. One could therefore question the advisability of separating out the nervous system for a special detailed study in our age of overspecialization. The main purpose of the present Handbook is not to fragment further our approach or under- standing of living phenomena, but, on the contrary, to try to summarize and integrate as much of the available information and thinking on...
Life, either as we think of it in the abstract in its highest sense, or life, as we think of it in terms of a compact living organism, is obviously th...
That chemicals (although not always called by this name) affect the brain and its functions, such as behavior, has been known for thousands of years. It is therefore surprising that the concept that chemical mechanisms are at least partially responsible for the complex functions of the brain is so recent. Investigation of the closely interlinked biophysical and biochemical proper- ties of the nervous system has achieved many notable successes in recent years and is the most exciting development in 20th-century science. Although all the morphology, the activity, and the alteration of the...
That chemicals (although not always called by this name) affect the brain and its functions, such as behavior, has been known for thousands of years. ...
When the projected volumes of the Handbook are completed, most of our current knowledge of the biochemistry of nervous systems will have been touched upon. A number of the chapters will have dealt with the correlations of the biochemical findings with morphological and physio- logical parameters as well. Considering the abysmal lack of such attempts, even in the recent past, this is a sign of great progress. If the reader's eventual goal is to derive the "laws" that relate various aspects of animal and human behavior to underlying physiological and biochemical function, these admirable...
When the projected volumes of the Handbook are completed, most of our current knowledge of the biochemistry of nervous systems will have been touched ...
It has been recognized for more than a thousand years that the function of the brain, like the function of the other organs of the body, is determined by its physical, chemical, and biological properties. Evidence that even its highest functions could be explained by these properties was gathered only in recent years, however; these findings, which clearly have to be confirmed by a great deal of further experimental evidence, indicate that most, if not all, of the functions of the brain are based on its bio- chemical and biophysical mechanisms. This at first hearing may sound rather simple,...
It has been recognized for more than a thousand years that the function of the brain, like the function of the other organs of the body, is determined...
More than for any other volume of the Handbook of Neurochemistry, the chap- ters in this volume on Pathological Neurochemistry deal with the interface of the laboratory bench with the patient's bedside. Most of the chapters reflect the confluence of basic scientists, clinical investigators, and physicians. Con- sidered here are many of the more important disorders that afflict the nerves, muscles, spinal cord, and/or brain of mankind throughout the world. There are well over 500 such disorders. And our understanding of their nature and of measures for effective prevention or treatment depends...
More than for any other volume of the Handbook of Neurochemistry, the chap- ters in this volume on Pathological Neurochemistry deal with the interface...