Kategoria BISAC: Medical >> Immunology

Fungal immunology, an expanding field of research, studies the interaction between fungi and the immune system. Modulated immunity as well as evasive mechanisms played by fungi all contribute to the chronicity and reoccurrence of fungal infections. Hypersensitivity to various fungal elements plays a major role in the pathogenesis of many diseases.

This book will serve as a comprehensive review of all known immune mechanisms for common medically important fungal pathogens. Its novelty lies in the organization: Rather than chapters devoted to specific fungi, chapters are organized by...

Research indicates that most neurodegenerative diseases, systemic amyloidoses and many others, arise from the misfolding and aggregation of an underlying protein. This is the first book to discuss significant achievements in protein structure-function relationships in biochemistry, molecular biology and molecular medicine. The authors summarize recent progress in the understanding of the relationships between protein misfolding, aggregation and development of protein deposition disorders.

Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses, and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in the field will contribute to this book, which will present a state-of-the-art view on these enzymes at a time when our understanding of their function is growing ever more rapidly and...

The Air Spora is an illustrated guide to trapping, identifying and quantifying airborne biological particles such as fungus and plant spores and pollen. This book will be of use to anyone interested in aerobiology or studying applied aspects such as dispersal and effect of allergens, or human, animal and plant pathogens. Including a comprehensive review of what is in the air and detailing the historical development of theories leading to modern aerobiology, the book explains the fundamental processes behind airborne dispersal and techniques used to sample, identify and quantify biological...

This book covers in detail contemporary hypotheses and studies related to the immunology of implantation and provides a practical approach for the application of basic reproductive immunology research to pregnancy complications such as preeclampsia, pre-term labor and IUGR. Provides complete and up to date review of current knowledge of the role of the immune system during pregnancy and the interactions between the placenta and the maternal immune system.

Signal transduction through leukocyte receptors involves a variety of signaling molecules including kinases, phosphatases, adaptor proteins, small GTPases GTP exchange factors, membrane phospholipids as well as others. These signal transducers, regulated by inter- and intra-molecular interactions, as well as by various post-translational modifications, lead to the activation of transcription factors that mediate cellular differentiation and growth, effector cell functions, and apoptotic cell death. Several investigators from various parts of the world convened at the 3^rd...

Psychoneuroimmunology is the study of interactions between the brain and the immune system. This book provides a clearly written summary of behavioral, neural and endocrine regulation of immune responses and of the effects of immune system activity on neural and endocrine functions and behavior. The underlying premise is that the brain and immune system represent a single, integrated system of defense.

Taurine (2-aminoethanesulfonic acid) is an enigmatic compound abounding in animal tissues. It is present at relatively high concentrations in all electrically excitable tissues such as the brain, sensory organs, the heart, and in certain endocrine glands. Some of its physiological functions are already established, for example as an essential nutrient during development and as a neuromodulator or osmolyte, but the cellular mechanisms are still mostly a matter of conjecture. Moreover, there are a number of other putative functions of taurine less well known at present. The 15th...

Dendritic cells play the most vital part in inducing anti-viral immune responses in HIV and AIDS among many other viruses. Research on dendritic cells (DCs) is emerging as a fundamental aspect for the comprehension of the mechanisms underlying the pathogenesis of viral diseases as well as for the progress on the development of prophylactic and therapeutic vaccines.

This volume focuses on the role of DCs in the pathogenesis and immunity of HIV-1 infection. It has recently been clarified that DCs are important targets and reservoirs of HIV and may play an important role in...