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Bioinformatics for Immunomics
ISBN: 9781461424857 / Angielski / Miękka / 192 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Like many words, the term "immunomics" equates to different ideas contingent on context. For a brief span, immunomics meant the study of the Immunome, of which there were, in turn, several different definitions. A now largely defunct meaning rendered the Immunome as the set of antigenic peptides or immunogenic proteins within a single microorganism - be that virus, bacteria, fungus, or parasite - or microbial population, or antigenic or allergenic proteins and peptides derived from the environment as a whole, containing also proteins from eukaryotic sources. However, times have changed and...
Like many words, the term "immunomics" equates to different ideas contingent on context. For a brief span, immunomics meant the study of the Immunome,...
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805,10 |
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Antibody Engineering: Methods and Protocols, Second Edition
ISBN: 9781617799730 / Angielski / Twarda / 734 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. More than ever, antibodies are being recognized as a major drug modality in a variety of diseases, including cancer, autoimmune diseases, infectious diseases, or even neurodegenerative disorders. Over 30 therapeutic antibodies have been approved and novel molecules are entering clinical trials at an average rate of 50 per year and that is predicted to continue well into the future. Notwithstanding the many achievements already made in the field, there is still a lot of room for improvements for these molecules in terms of activity, and a plethora of approaches have been attempted to... More than ever, antibodies are being recognized as a major drug modality in a variety of diseases, including cancer, autoimmune diseases, infectiou... |
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805,10 |
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Antigen Processing: Methods and Protocols
ISBN: 9781627032179 / Angielski / Twarda / 589 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This Methods in Molecular Biology book offers a comprehensive set of protocols for studying presentation of antigens produced in the standard processing pathways for MHC class I and class II molecules. Includes materials lists, tips and troubleshooting advice.
This Methods in Molecular Biology book offers a comprehensive set of protocols for studying presentation of antigens produced in the standard processi...
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805,10 |
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Signal Transduction in Mast Cells and Basophils
ISBN: 9781461274353 / Angielski / Miękka / 423 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Mast cells and basophils are responsible for inflammatory and allergic reactions. As such, the signals that generate these responses and how their pathways of action work are the focus of much present day research into allergy and inflammation. This book focuses primarily on the molecular mechanisms that govern mast cell and basophil cell biology and function, as well as providing a comprehensive summary of the field of signal transduction and also giving insights into areas that have therapeutic potential. The book provides detailed insights into mast cell and basophil growth and...
Mast cells and basophils are responsible for inflammatory and allergic reactions. As such, the signals that generate these responses and how their pat...
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805,10 |
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Autophagy in Infection and Immunity
ISBN: 9783642260377 / Angielski / Miękka / 339 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Autophagy is a fundamental biological process that enables cells to autodigest their own cytosol during starvation and other forms of stress. It has a growing spectrum of acknowledged roles in immunity, aging, development, neurodegeneration, and cancer biology. An immunological role of autophagy was first recognized with the discovery of autophagy's ability to sanitize the cellular interior by killing intracellular microbes. Since then, the repertoire of autophagy's roles in immunity has been vastly expanded to include a diverse but interconnected portfolio of regulatory and effector... Autophagy is a fundamental biological process that enables cells to autodigest their own cytosol during starvation and other forms of stress. It ha... |
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Gene Therapy for Autoimmune and Inflammatory Diseases
ISBN: 9783034803069 / Angielski / Miękka / 239 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this monograph about gene therapy of autoimmune and inflammatory d- orders we have gathered international experts and leaders from different fields to review the state of the art advances on topics ranging from disease entities to vectors and engineered cells. The different approaches described in each chapter take into consideration the biomedical knowledge of these diseases and address the complexities of delivering long-term genetic interventions. Gene therapy also serves as a testing ground for new therapeutic entities and helps provide proof of principle for their potential...
In this monograph about gene therapy of autoimmune and inflammatory d- orders we have gathered international experts and leaders from different fields...
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805,10 |
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From Basic Immunology to Immune-Mediated Demyelination
ISBN: 9788847021792 / Angielski / Miękka / 315 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book covers the immunological and clinical aspects of central and peripheral nervous system inflammatory diseases characterized by myelin damage. Leading scientists in the field have summarized in short reviews the state of the art of neuroimmunology, with particular emphasis on basic aspects of the regulation of immune responses during demyelinating disorders. The volume will be helpful to neuroimmunologists, but also to clinicians which will find a clear and concise understanding of the main features of neuroinflammatory disease.
This book covers the immunological and clinical aspects of central and peripheral nervous system inflammatory diseases characterized by myelin damage....
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The Tumor Immunoenvironment
ISBN: 9789400762169 / Angielski / Twarda / 745 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Interaction between malignant cells and their surrounding tissue plays a crucial role in tumor growth, invasiveness and spreading to the distant organs. New findings provide evidence of a principal importance of the immune cells for controlling this interaction and orchestrating multiple events in the tumor microenvironment. The balance between immune cells that support tumor progression and immune cells that sustain tumor-controlling immune surveillance is tightly regulated by various factors originated from both the malignant and non-cancerous cells in the tumor microenvironment. Analysis...
Interaction between malignant cells and their surrounding tissue plays a crucial role in tumor growth, invasiveness and spreading to the distant organ...
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805,10 |
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Replicating Vaccines: A New Generation
ISBN: 9783034803168 / Angielski / Miękka / 447 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines. Historically, live vaccines have been either directly derived from a natural source or attenuated by empirical approaches using serial passages and host cell adaptation. Currently, we are witnessing a quantum leap in our technological capabilities to specifically modify the genetic make-up of viruses and bacteria, making it possible to generate improved live vaccines and to develop completely new...
Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilitie...
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805,10 |
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Phylogenetic Perspectives on the Vertebrate Immune System
ISBN: 9781461354819 / Angielski / Miękka / 383 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book contains the proceedings of the first meeting on invertebrate immunity ever sponsored as a summer research conference by the Federation of American Societies for Experimental Biology (FASEB). The conference was held in Copper Mountain, CO from July 11-16, 1999. It was a an extension of a New York Academy of Sciences meeting entitled "Primordial Immunity: Foundations for the Vertebrate Immune System" held on May 2-5,1993 at the Marine Biological Laboratories in Woods Hole, MA. The proceedings of that meeting were published in The Annals of the New York Academy of Sciences (volume...
This book contains the proceedings of the first meeting on invertebrate immunity ever sponsored as a summer research conference by the Federation of A...
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805,10 |
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Biotechnology of Hairy Root Systems
ISBN: 9783642390180 / Angielski / Twarda / 159 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Victor P. Bulgakov, Yuri N. Shkryl, Galina N. Veremeichik, Tatiana Y. Gorpenchenko and Yuliya V. Vereshchagina: Recent Advances in the Understanding of Agrobacterium rhizogenes-Derived Genes and Their Effects on Stress Resistance and Plant Metabolism. Le Zhao, Guy W. Sander and Jacqueline V. Shanks: Perspectives of the Metabolic Engineering of Terpenoid Indole Alkaloids in Catharanthus roseus Hairy Roots. Jian Wen Wang and Jian Yong Wu: Effective Elicitors and Process Strategies for Enhancement of Secondary Metabolite Production in Hairy Root Cultures. Amanda R. Stiles and Chun-Zhao Liu:...
Victor P. Bulgakov, Yuri N. Shkryl, Galina N. Veremeichik, Tatiana Y. Gorpenchenko and Yuliya V. Vereshchagina: Recent Advances in the Understanding o...
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805,10 |
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Immunopharmacology in Autoimmune Diseases and Transplantation
ISBN: 9780306439940 / Angielski / Twarda / 420 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book incorporates the latest advances in immunopharmacological treatment. One objective has been to provide appropriate bridges between the basic sciences of immunology and pharmacology on the one hand and clinical medicine on the other. A further intention has been to emphasize those advances in immunology and pharmacology that are of clinical importance while retaining those facts that, while not new, remain clinically useful. The immunology section provides the necessary background for immunopharmacologi cal treatment. The chapters on individual cell types include normal surface...
This book incorporates the latest advances in immunopharmacological treatment. One objective has been to provide appropriate bridges between the basic...
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805,10 |
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Therapeutic Antibodies: Methods and Protocols
ISBN: 9781934115923 / Angielski / Twarda / 585 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over 2000 years ago in China, antibodies elicited by early forms of vaccination likely played a major role in the protection of the population from infectious agents. Vac- nation has been further developed in Europe and described by Edward Jenner in the late-eighteenth century, then successfully implemented worldwide. The idea to use theactiveingredientinthebloodofvaccinated(orimmunized)animalsorhumansfor the treatment of diseases came a century later. It was made possible by a series of discoveries, suchastherealizationthattheserumfromanimalsimmunizedwithtoxins, for example, diphtheria toxin...
Over 2000 years ago in China, antibodies elicited by early forms of vaccination likely played a major role in the protection of the population from in...
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805,10 |
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The Impact of Biotechnology on Autoimmunity
ISBN: 9789401044844 / Angielski / Miękka / 137 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The term "autoimmunity" has been used to categorize a number of different diseases of unknown etiology. The term as applied to many of these diseases would probably be interpreted best as "autoreactivity," as the clinical phenotypes are often characterized by an inflammatory-like accumulation of activated cells of the immune system at sites of obvious damage of normal cells and/or tissue. The reasons as to why an immune system should attack itself are far from clear, although the association with specific infectious diseases in genetically susceptible people remains perhaps our best lead. The...
The term "autoimmunity" has been used to categorize a number of different diseases of unknown etiology. The term as applied to many of these diseases ...
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Molecular Basis of Lymphokine Action
ISBN: 9781461289432 / Angielski / Miękka / 482 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The Fifth International Lymphokine Workshop was convened in Clearwater Beach, Florida, January 11-15, 1987. The theme chosen for the meeting was 'The Molecular Basis of Lymphokine Action," which reflected the opinion of the organizers as to how far the field had moved since the first Lymphokine Workshop only eleven years ago. As was evident at the last Lymphokine Workshop held in 1985, the contribution of molecular biology, particularly in the cloning of lymphokine genes, continues to play an important role in clarifying the structure of lymphokines, providing recombinant (read "pure")...
The Fifth International Lymphokine Workshop was convened in Clearwater Beach, Florida, January 11-15, 1987. The theme chosen for the meeting was 'The ...
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Hypoxia: Through the Lifecycle
ISBN: 9781461347538 / Angielski / Miękka / 372 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The International Hypoxia Symposium convenes biannually to bring together international experts from many fields to explore the state of the art in normal and pathophysiological responses to hypoxia. Representatives from five continents and 32 countries joined together in February 2003 for four days in the dramatic mountains of Banff, Alberta. As editors of the Proceedings of the International Hypoxia Symposia, we strive to maintain a 26 six year tradition of presenting a stimulating blend of clinical and basic science papers focused on hypoxia. Topics covered in 2003 include hibernation and...
The International Hypoxia Symposium convenes biannually to bring together international experts from many fields to explore the state of the art in no...
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Nitric Oxide and Infection
ISBN: 9781475786170 / Angielski / Miękka / 518 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Familiarity with nitric oxide is essential to a modern understanding of pathophysiologic mechanisms of infectious disease. Recent research has established nitric oxide and related reactive nitrogen intermediates to be important molecular mediators of diverse physiologic processes such as control of vascular tone, regulation of the immune system, and microbial and tumor cell growth. This book contains chapters by the leading researchers in the field and examines the biology and biochemistry of nitric oxide and its role in a variety of specific infections ranging from sepsis,...
Familiarity with nitric oxide is essential to a modern understanding of pathophysiologic mechanisms of infectious disease. Recent research has estab...
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Antiviral Chemotherapy 4: New Directions for Clinical Application and Research
ISBN: 9781475792119 / Angielski / Miękka / 440 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The three years since our last conference in San Francisco have again seen a dramatic expansion of the number of antivirals either licensed or in the late stages of clinical trials. d4T is now licensed for HIV infection, famciclovir and the oral pro-drug of acyclovir, valacyclovir, are now licensed for VZV infections in some countries. Moreover. oral ganciclovir, cidofovir, and sorivudine are not far behind. Clinical trials with the second-site reverse transcriptase inhibitors and the protease inhibitors for HlV infection are proceeding rapidly and on a broad scale, and the preliminary...
The three years since our last conference in San Francisco have again seen a dramatic expansion of the number of antivirals either licensed or in the ...
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805,10 |
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Activating and Inhibitory Immunoglobulin-Like Receptors
ISBN: 9784431679592 / Angielski / Miękka / 246 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A remarkable spectrum of novel immunoreceptors sharing related immunoglobulin-like domains and signaling potential has been identified in recent years. These receptors have attracted widespread interest because they resemble the TCR, BCR, and FcR complexes in their ability to serve as activating or inhibitory receptors on the cells that bear them. Moreover, they are well positioned to affect both innate and adaptive immunity. The full range of ligands for these new receptor families is still not known, and understanding of their physiological roles is far from complete. This volume is the...
A remarkable spectrum of novel immunoreceptors sharing related immunoglobulin-like domains and signaling potential has been identified in recent years...
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805,10 |
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Immunology of the Connective Tissue Diseases
ISBN: 9789401046275 / Angielski / Miękka / 406 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Connective tissue diseases demand study because of their frequency, morbidity and mortality. They present intriguing challenges in the fields of diagnosis, management and research. Their range has now expanded enormously so that no individual can master the whole subject, particularly as this relates to their immunological basis.
Immunology of Connective Tissue Diseases has been written by experts who are either clinical or basic scientists. The book presents up-to-date reviews of the immunological basis of connective tissue diseases as it impacts on diagnosis, pathogenetic... Connective tissue diseases demand study because of their frequency, morbidity and mortality. They present intriguing challenges in the fields of diagn...
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805,10 |
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