Fluid, Electrolyte, and Acid-Base Regulation
ISBN: 9781583481974 / Angielski / Miękka / 256 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. |
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cena:
151,19 zł |
Molecular Biology of Drug Addiction
ISBN: 9781588290601 / Angielski / Twarda / 346 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A comprehensive multidisciplinary review of the most relevant molecular, genetic, and behavioral approaches used to investigate the neurobiological basis of drug addiction. The authors explore the latest findings on opioid, psychostimulant, cannabinoid, alcohol, and nicotine addiction, provide fresh insights into the genetic basis of drug addiction and the new therapeutic perspectives these have opened. They describe the technology available to generate conditional knockout mice and show how these mice can reveal the molecular basis of opioid, psychostimulant, and cannabinoid addiction. They...
A comprehensive multidisciplinary review of the most relevant molecular, genetic, and behavioral approaches used to investigate the neurobiological ba...
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cena:
582,32 zł |
Antibody Engineering: Methods and Protocols
ISBN: 9781588290922 / Angielski / Twarda / 562 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The exquisite binding specificity of antibodies has made them valuable tools from the laboratory to the clinic. Since the description of the murine hybridoma technology by Kohler and Milstein in 1975, a phenomenal number of mo- clonal antibodies have been generated against a diverse array of targets. Some of these have become indispensable reagents in biomedical research, while others were developed for novel therapeutic applications. The attractiveness of an- bodies in this regard is obvious high target specificity, adaptability to a wide range of disease states, and the potential ability to...
The exquisite binding specificity of antibodies has made them valuable tools from the laboratory to the clinic. Since the description of the murine hy...
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cena:
582,32 zł |
Atomic Force Microscopy: Biomedical Methods and Applications
ISBN: 9781588290946 / Angielski / Twarda / 394 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The natural, biological, medical, and related sciences would not be what they are today without the microscope. After the introduction of the optical microscope, a second breakthrough in morphostructural surface analysis occurred in the 1940s with the development of the scanning electron microscope (SEM), which, instead of light (i. e., photons) and glass lenses, uses electrons and electromagnetic lenses (magnetic coils). Optical and scanning (or transmission) electron microscopes are called far-field microscopes because of the long distance between the sample and the point at which the image...
The natural, biological, medical, and related sciences would not be what they are today without the microscope. After the introduction of the optical ...
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cena:
582,32 zł |
P53 Protocols
ISBN: 9781588291066 / Angielski / Twarda / 280 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since the discovery of p53 as a tumor suppressor, numerous methods have evolved to reveal the unique structural features and biochemical functions of this protein. Several unique properties of p53 posed a challenge to understa- ing its normal function in the initial phase of its research. The low levels of p53 in normal cells, its stabilization under situations of genotoxic stress, induction of growth arrest, and apoptosis with stabilization of the protein, obstructed the visibility of its normal, unmutated function. The property of p53 that can sense a promoter and transactivate or inhibit...
Since the discovery of p53 as a tumor suppressor, numerous methods have evolved to reveal the unique structural features and biochemical functions of ...
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cena:
388,20 zł |
Chiral Separations: Methods and Protocols
ISBN: 9781588291509 / Angielski / Twarda / 432 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Many compounds of biological and pharmacological interest are as- metric and show optical activity. Approximately 40% of the drugs in use are known to be chiral and only about 25% are administered as pure enantiomers. It is well established that the pharmacological activity is mostly restricted to one of the enantiomers (eutomer). In several cases, unwanted side effects or even toxic effects may occur with the inactive enantiomer (distomer). Even if the side effects are not that drastic, the inactive enantiomer has to be meta- lized, which represents an unnecessary burden for the organism....
Many compounds of biological and pharmacological interest are as- metric and show optical activity. Approximately 40% of the drugs in use are known to...
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cena:
388,20 zł |
Igf and Nutrition in Health and Disease
ISBN: 9781588291905 / Angielski / Twarda / 359 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This text stands alone as it provides the first authoritative review on the role of nutrition as it pertains to the IGF system. By taking a multidisciplinary approach, the importance of nutrition and the IGF system in the pathology and treatment of conditions such as diabetes, renal failure, inflammatory bowel diseases, critical illness, wasting disease, neurological disorders, cardiovascular disease and cancer are explored. Even for health professionals not directly involved in IGF research, the text contributes greatly to the understanding of the mechanisms of growth arrest and metabolic...
This text stands alone as it provides the first authoritative review on the role of nutrition as it pertains to the IGF system. By taking a multidisci...
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cena:
582,32 zł |
Nitric Oxide Protocols
ISBN: 9781588292377 / Angielski / Twarda / 248 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It has been more than five years since the appearance of the first edition of Nitric Oxide Protocols. According to Medline, more than 32,500 publications dealing with nitric oxide have appeared in the primary literature in the int- vening time from 1999 to April 2004. These numbers attest to the continuing vitality of a field dealing with a deceptively simple, although extremely int- esting and promiscuous molecule, nitric oxide. Despite its apparent chemical simplicity, nitric oxide continues to amaze, with an extremely wide spectrum of functions and effects. In particular, the last few...
It has been more than five years since the appearance of the first edition of Nitric Oxide Protocols. According to Medline, more than 32,500 publicati...
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cena:
388,20 zł |
Ubiquitin-Proteasome Protocols
ISBN: 9781588292520 / Angielski / Twarda / 381 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A collection of cutting-edge techniques for studying ubiquitin-dependent protein degradation via the proteasome. The topics covered range broadly from basic biochemistry to cellular assays to discovery techniques using mass spectrometric analysis. These biochemical and cellular methods are necessary to explore the ubiquitin-proteasome system and ubiquitin-proteasome-dependent functions. State-of-the-art and user-friendly, Ubiquitin-Proteasome Protocols offers novice and experienced bench scientists alike a thorough compendium of readily reproducible techniques that will accelerate discovery,...
A collection of cutting-edge techniques for studying ubiquitin-dependent protein degradation via the proteasome. The topics covered range broadly from...
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cena:
388,20 zł |
Protein Nanotechnology: Protocols, Instrumentation, and Applications
ISBN: 9781588293107 / Angielski / Twarda / 466 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Protein Nanotechnology: Protocols, Instrumentation, and Applications is an authoritative reference for a broad audience involved in nanotechnology research and in the teaching, learning, and practice of nanotechnology for genomics, proteomics, bioengineering, and medicine. This volume presents the most recent scientific and technological advances of nanobiotechnology, as well as the practical methods and applications of it. Each chapter provides introductory material with an overview of the topic of interest; a description of methods, protocols, instrumentation, and applications; and a...
Protein Nanotechnology: Protocols, Instrumentation, and Applications is an authoritative reference for a broad audience involved in nanotechnology res...
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cena:
582,32 zł |
Phosphodiesterase Methods and Protocols
ISBN: 9781588293145 / Angielski / Twarda / 336 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Adenosine 3,5 -cyclic monophosphate (cAMP) and guanosine 3,5 -cyclic monophosphate are ubiquitous nucleotides that have been described as the first and second messengers. In concert with intracellular calcium and IP3, they play a major role in the control of intracellular signaling, which orchestrates normal and pathophysiological responses. Downstream from the cyclic nucleotide synthesis by adenylyl and guanylyl cyclases, the multigenic family of cyclic nucleotide phosphodiesterases (PDEs), by specifically hydrolyzing cyclic nucleotides, controls cAMP and cGMP levels to maintain a basal...
Adenosine 3,5 -cyclic monophosphate (cAMP) and guanosine 3,5 -cyclic monophosphate are ubiquitous nucleotides that have been described as the first an...
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cena:
388,20 zł |
Stroke Genomics: Methods and Reviews
ISBN: 9781588293336 / Angielski / Twarda / 351 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. With sequencing of the human genome now complete, deciphering the role of gene function in human neurological pathophysiology is a promise that has yet to be realized. More than most diseases, stroke has been keenly studied from a genomic perspective. Studies are numerous and incorporate data on stroke inheritance, chromosomal loci of risk, preclinical models of stroke, and differential gene expression of brain injury, repair, and recovery. The problem is no longer a lack of information but one of interpretation and prioritization of what we do know. The aims of Stroke Genomics: Methods and...
With sequencing of the human genome now complete, deciphering the role of gene function in human neurological pathophysiology is a promise that has ye...
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cena:
388,20 zł |
Therapeutic Proteins: Methods and Protocols
ISBN: 9781588293909 / Angielski / Twarda / 482 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. With the recent completion of the sequencing of the human genome, it is widely anticipated that the number of potential new protein drugs and targets will escalate at an even greater rate than that observed in recent years. However, identification of a potential target is only part of the process in developing these new next generation protein-based "drugs" that are increasingly being used to treat human disease. Once a potential protein drug has been identified, the next rate-limiting step on the road to development is the production of sufficient authentic material for testing, charact-...
With the recent completion of the sequencing of the human genome, it is widely anticipated that the number of potential new protein drugs and targets ...
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cena:
582,32 zł |
Pesticide Protocols
ISBN: 9781588294104 / Angielski / Twarda / 504 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. A comprehensive collection of robust methods for the detection of pesticide compounds or their metabolites useful in food, environmental, and biological monitoring, and in studies of exposure via food, water, air, and the skin or lungs. The readily reproducible methods range from gas and liquid chromatography coupled to mass spectrometry detection and other classic detectors, to capillary electrophoresis and immunochemical or radioimmunoassay methods. The authors have focused on extraction and cleanup procedures, in order to develop and optimize more fullyautomated and miniaturized methods,...
A comprehensive collection of robust methods for the detection of pesticide compounds or their metabolites useful in food, environmental, and biologic...
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cena:
582,32 zł |
Bioarrays: From Basics to Diagnostics
ISBN: 9781588294760 / Angielski / Twarda / 269 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Bioarrays: From Basics to Diagnostics provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. The entire volume is broken into four sections Bioarray Technology Platforms, Biomarkers and Clinical Genomics, Biomarker Identification Using Clinical Proteomics and Glycomics, and Emerging Technologies in Diagnostics that create one well-integrated work. Particular emphasis is placed on DNA, protein, and carbohydrate biochips. The volume also looks extensively at oligonucleotides, cDNA,... Bioarrays: From Basics to Diagnostics provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in t... |
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cena:
388,20 zł |
Molecular Motors: Methods and Protocols
ISBN: 9781588296658 / Angielski / Twarda / 252 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Molecular motor proteins comprise three protein superfamilies: kinesins, dyneins and myosins. Together, these proteins produce force for movement in an incredibly wide variety of cellular processes including vesicular transport, cell division, nuclear migration, muscle contraction, mechanochemical transduction, among others. In addition, molecular motors are expressed in both simple eukaryotes and in a tissue specific manner in higher cells. This methods volume explores the extreme functional and structural diversity of molecular motors and presents methods relevant to each motor family.... Molecular motor proteins comprise three protein superfamilies: kinesins, dyneins and myosins. Together, these proteins produce force for movement i... |
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cena:
388,20 zł |
Principles of Biochemistry: Pearson New International Edition
ISBN: 9781292021744 / Angielski / Miękka / 800 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Principles of Biochemistry provides a concise introduction to fundamental concepts of biochemistry, striking the right balance of rigor and detail between the encyclopedic volumes and the cursory overview texts available today. Widely praised for accuracy, currency, and clarity of exposition, the Fifth Edition offers a new student-friendly design, an enhanced visual program, new Application Boxes, contemporary research integrated throughout, and updated end-of-chapter problems.
Principles of Biochemistry provides a concise introduction to fundamental concepts of biochemistry, striking the right balance of rigor and detail bet...
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cena:
549,31 zł |
Ionospheric Tomography
ISBN: 9783540004042 / Angielski / Twarda / 260 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Authored by leading international researchers, this monograph introduces and reviews developed tomograhic methods for discovering 2D and 3D structures of the ionosphere, and discusses the experimental implementation of these methods. The detailed derivations and explanations make this book an excellent starting point for non-specialists. Authored by leading international researchers, this monograph introduces and reviews developed tomograhic methods for discovering 2D and 3D structu... |
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cena:
582,32 zł |
MR Cholangiopancreatography: Atlas with Cross-Sectional Imaging Correlation
ISBN: 9783540222699 / Angielski / Twarda / 414 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Magnetic resonance cholangiopancreatography (MRCP) is a novel non-invasive technique for diagnosis of pancreatic-biliary disease. The purpose of this book is to highlight the advantages, limitations and indications of MRCP. Specific examples have been selected to showcase the utility of this technique in a large variety of clinical conditions. Each example is purposefully used to stress important technical features, to give practical advice, or to discuss the role of MRCP in specific clinical situations. Important features of the book are the high quality of the illustrations, the reduction...
Magnetic resonance cholangiopancreatography (MRCP) is a novel non-invasive technique for diagnosis of pancreatic-biliary disease. The purpose of this ...
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cena:
776,43 zł |
Radiological English
ISBN: 9783540293286 / Angielski / Miękka / 324 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This is an introductory book to radiological English on the basis that there are a lot of radiologists, radiology residents, radiology nurses, radiology students, and radiographers worldwide whose English level is indeterminate because their reading skills are much higher than their fluency. It is intended to help those health care professionals who need English for their work but do not speak English on a day-to-day basis. This is an introductory book to radiological English on the basis that there are a lot of radiologists, radiology residents, radiology nurses, radi... |
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cena:
291,14 zł |