Kategoria BISAC: Medical >> Biochemistry

Fibrogenesis: Cellular and Molecular Basis is the first volume to provide a synopsis of the rapid progress that has been documented in fibrogenesis over last couple of years, which significantly enhanced our understanding of the pathomechanisms of fibrotic diseases. Knowledge on molecular and celluar basis of fibrotic diseases has provided opportunities to develop selective and effective gene-based therapeutic options.

The chapters in this book have been selected to provide comprehensive information on fibrogenesis, which is not limited to any specific organ....

The goal of this book is to have the authors write in a crisp and concise fashion a summary of the most important and biologically relevant developments and the clinical importance of vitamin D in their particular area of expertise. The Editor is not interested in this book being an encyclopedia of information, but rather a user friendly source that basic scientists, nutritionists, health care professionals and specialists in calcium, vitamin D, and bone health can draw upon for useful up-to-date information on vitamin D and health.

Disordered, as opposed to ordered, proteins cover nearly half of the sequence space in various proteomes, yet to date they have received little mention in references. This work provides the first comprehensive reference on the structure, function, and evolution of intrinsically disordered proteins (IDPs). After an overview of protein science principles, it examines biophysical methods for characterizing IDPs, addressing computational approaches as well as major classes of relevant algorithms. The text also discusses structural and functional classification, including functional advantages...

In recent years, much information has been revealed concerning the essential role of helicases, the enzymes that utilize the energy derived from nucleoside triphosphate hydrolysis to unwind the double stranded helical structure of nucleic acids. In Helicases: Methods and Protocols, this topic is explored by leading international scientists who have contributed significantly to our current understanding of helicases and the ways in which they function. Chapters include methods for the production and purification of helicases from different species, as well as detailed studies of...

Diabetes is now reaching epidemic proportions, and the associated complications of this disease can be disabling and even life-threatening. In Type 2 Diabetes: Methods and Protocols, leading investigators provide up-to-date explanations of commonly used laboratory protocols used in diabetes research. Covering the commonly described in vivo and in vitro model systems, the volume ultimately leads to an overall view of how cellular dysfunction and degeneration leads to susceptibility and diabetes disease progression. Written in the highly successful Methods in Molecular Biology...

This volume is a collection of chapters dealing with imaging diagnosis and interventional therapies in musculoskeletal diseases. The different topics are disease-oriented and encompass all the relevant imaging modalities.

Carefully structured within five sections, each biochemical, physiological or medical subject that is covered in the book is presented in one complete chapter. Consequently, each subject...

By combining the tools of organic chemistry with those of physical biochemistry and cell biology, Non-Natural Amino Acids aims to provide fundamental insights into how proteins work within the context of complex biological systems of biomedical interest.

The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. With more than 400 volumes...

In the 11 years since this atlas first published, the immunology field has experienced an exponential increase in information. Besides the unprecedented advances in knowledge of cell receptors and signal transduction pathways, an avalanche of new information has been gleaned from contemporary research concerning cytokines and chemokines, with special reference to their structure and function.

Visually Enhances Definitions in the Language of Immunology
Now with more than 1300 illustrations, Atlas of Immunology, Third Edition is the most thorough...

The physical-chemical properties of the omega-3 fatty acid DHA (docosahexaenoic acid) enable it to facilitate rapid biochemical processes in the membrane. This effect has numerous benefits, including those involved in the growth of bacteria, rapid energy generation, human vision, brain impulse, and photosynthesis, to name a few. Yet DHA also carries risks that can lead to cellular death and disease. Omega-3 Fatty Acids and the DHA Principle explores the roles of omega-3 fatty acids in cellular membranes ranging from human neurons and swimming sperm to deep sea bacteria,...

Molecular imaging plays an important role in drug discovery and advanced medical practice. A symposium of world leaders in drug research and development, molecular imaging, and medical therapy including regenerative treatment and radiation therapy has led to the publication of this book. Based on the proceedings of the symposium, many excellent ideas and valuable discussions are introduced that will guide the reader toward new advances in photon detection and protein modification as well as new developments in molecular imaging itself. Both protein modification and photon detection are...