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Gene Transfer and Expression in Mammalian Cells: Volume 38
ISBN: 9780444513717 / Angielski / Twarda / 680 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The production of proteins in mammalian cells is an important tool in numerous scientific and commercial areas. For example, proteins for human therapy, vaccination or diagnostic applications are typically produced in mammalian cells. Gene cloning, protein engineering, biochemical and biophysical characterization of proteins also require the use of gene expression in mammalian cells. Other applications in widespread use involve screening of libraries of chemical compounds in drug discovery, and the development of cell-based biosensors. This book presents a state-of-the-art comprehensive...
The production of proteins in mammalian cells is an important tool in numerous scientific and commercial areas. For example, proteins for human therap...
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cena:
1217,06 |
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Artificial Nucleases
ISBN: 9783540201120 / Angielski / Twarda / 292 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the immediate and very important applications they can find in the emerging fields of biotechnology and pharmacology. There are essentially two classes of these agents - nucleases that occur naturally inside cells and synthetically produced artificial nucleases. The first class includes protein enzyme nucle ases and catalytic RNA structured ribozymes that perform cleavage of the phosphodiester bonds in nucleic acids according to a hydrolytic pathway...
The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the ...
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cena:
1221,84 |
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Biomedical Image Registration: Second International Workshop, WBIR 2003, Philadelphia, PA, USA, June 23-24, 2003, Revised Papers
ISBN: 9783540203438 / Angielski / Miękka / 410 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The 2nd International Workshop on Biomedical Image Registration (WBIR) was held June 23-24, 2003, at the University of Pennsylvania, Philadelphia. Following the success of the ?rst workshop in Bled, Slovenia, this meeting aimed to once again bring together leading researchers in the area of biomedical image registration to present and discuss recent developments in the ?eld. Thetheory, implementationandapplicationofimageregistrationinmedicine have become major themes in nearly every scienti?c forum dedicated to image processingandanalysis. Thisintenseinterestre?ectsthe?eld'simportantrolein...
The 2nd International Workshop on Biomedical Image Registration (WBIR) was held June 23-24, 2003, at the University of Pennsylvania, Philadelphia. Fol...
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cena:
203,61 |
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Metabolic Engineering
ISBN: 9783540418481 / Angielski / Twarda / 184 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology, developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae...
Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of ...
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cena:
814,55 |
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Prostaglandins, Leukotrienes, Lipoxins, and Paf: Mechanism of Action, Molecular Biology, and Clinical Applications
ISBN: 9780306440557 / Angielski / Twarda / 461 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The field of eicosanoid metabolism and function continues to grow. Synthesis of the prostaglandins from essential fatty acids was first described by Bergstrom and Sarnuelsson in 1964. The thromboxanes were discovered in 1975, the prostacyclins, by Moncada and Vane, in 1976, and the leukotrienes by Samuelsson in 1979. A new class of biologically active arachidonic acid metabolites named lipoxins was announced by Bengt Samuelsson in May 1984. Since that time major advances have been made in the molecular biology of the eicosanoids including the cloning of prostaglandin synthases and 5, 12, and...
The field of eicosanoid metabolism and function continues to grow. Synthesis of the prostaglandins from essential fatty acids was first described by B...
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cena:
1082,70 |
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Molecular Modeling of Proteins
ISBN: 9781588298645 / Angielski / Twarda / 390 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Molecular modeling has undergone a remarkable transformation in the last 20 years. This book provides thorough introductions and a compilation of step-by-step methods applicable to problems faced by non-specialists especially those new to the software packages used in molecular modeling. Tips on troubleshooting and avoiding common pitfalls are included in the book, along with chapters covering a wide range of subjects. Links to downloadable software are also provided."
Molecular modeling has undergone a remarkable transformation in the last 20 years. This book provides thorough introductions and a compilation of s... |
cena:
610,90 |
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Macromolecular Medical Biochem
ISBN: 9780521278287 / Angielski / Miękka / 280 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This text aims to bring to the attention of undergraduate students of biochemistry the many exciting developments in cell and molecular biology in recent years and their important implications for the practice of medicine. Emphasis is placed on such topics as membrane structure and function and hormone action and secretion, where current knowledge of macromolecular and cellular structure and function will contribute most to understanding the underlying pathology of common multifactorial diseases. The book also outlines the basic features of recombinant DNA techniques and their probable impact...
This text aims to bring to the attention of undergraduate students of biochemistry the many exciting developments in cell and molecular biology in rec...
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cena:
288,67 |
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Biological Magnetic Resonance: In Vivo Carbon-13 NMR
ISBN: 9780306458866 / Angielski / Twarda / 255 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume constitutes a compilation of the latest experiments and theories on a rapidly evolving and maturing field in MRI/MRS, which is the use of the stable isotope 13-C. The 13-C is used to probe the chemistry, mechanism, and function in living systems.
All the chapters are written by experts in the field who discuss topics such as Tracer Theory and the Suitability of 13-C NMR', Applications of 13-C to Studies of Human Brain Metabolism', etc. This volume constitutes a compilation of the latest experiments and theories on a rapidly evolving and maturing field in MRI/MRS, which is the use of ...
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cena:
814,55 |
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Progress in Medicinal Chemistry: Volume 46
ISBN: 9780444530189 / Angielski / Twarda / 407 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Appropriate selection of biochemical targets is one of the most important drivers of cost effectiveness in the discovery of new medicines. Despite the many advances in genetics, genomics and systems biology, 'validation' of a target is not achieved until therapeutic efficacy is demonstrated by a drug candidate. Volume 46 of this series reviews the medicinal chemistry aimed at six diverse targets from which important new medicines are emerging:
* HIV integrase (discovery of the first-in-class inhibitor drug raltegravir) * 11-beta-Hydroxysteroid dehydrogenase (new approach to... Appropriate selection of biochemical targets is one of the most important drivers of cost effectiveness in the discovery of new medicines. Despite the...
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cena:
695,46 |
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Electron Paramagnetic Resonance in Biochemistry and Medicine
ISBN: 9780306465314 / Angielski / Twarda / 268 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Electron Paramagnetic Resonance (EPR) spectroscopy - also sometimes termed Electron Spin Resonance spectroscopy - has manifold potential uses in biochemistry and medicine. The paramount importance of EPR spectroscopy applied to biological tissues and fluids is that it identifies the changes in redox processes that contribute to disease.
EPR spectroscopy has come a long way from its original use to detect malignant tumors. For example, the development and later refinement of methods of low-temperature registration of biological tissues widened the scope of EPR spectroscopy. Innovations... Electron Paramagnetic Resonance (EPR) spectroscopy - also sometimes termed Electron Spin Resonance spectroscopy - has manifold potential uses in bioch...
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cena:
407,25 |
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Fundamentals of Tissue Engineering and Regenerative Medicine
ISBN: 9783540777540 / Angielski / Twarda / 1049 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. "Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are... "Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regen... |
cena:
1344,03 |
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Human Blood Plasma Proteins: Structure and Function
ISBN: 9780470016749 / Angielski / Twarda / 538 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include:
Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and functio...
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cena:
734,95 |
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Growth Factors, Part a
ISBN: 9780762300914 / Angielski / Twarda / 575 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This series provides a variety of different discussions on topics within the field of growth factors and cytokines in health and disease. This series provides a variety of different discussions on topics within the field of growth factors and cytokines in health and disease. |
cena:
657,04 |
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Systems, Part a
ISBN: 9780762301188 / Angielski / Twarda / 545 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume deals with some of the multiple systems that growth factors and cytokines affect. The role of growth factors and cytokines on foetal development, in the immune and haemopoietic systems as well as in the skeletal and reproductive systems are covered. Various cancers are examined in a number of the chapters. This is the third and concluding volume of the treatise on growth factors and cytokines in health and disease. This volume deals with some of the multiple systems that growth factors and cytokines affect. The role of growth factors and cytokines on foetal de... |
cena:
657,04 |
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Calcium Hunger: Behavioral and Biological Regulation
ISBN: 9780521795517 / Angielski / Miękka / 218 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book brings together the behavioral, physiological, and neuroendocrine regulation of calcium. An understanding of how the brain orchestrates whole-body demands for calcium is introduced. The approach is one in which behavior in addition to physiology serves bodily maintenance. The book links basic and clinical literature surrounding calcium homeostasis, as a wide variety of clinical syndromes are tied to calcium metabolism. Because calcium is so important during life stages particular to women, an emphasis is placed on the relevance of calcium to women's health throughout the book,...
This book brings together the behavioral, physiological, and neuroendocrine regulation of calcium. An understanding of how the brain orchestrates whol...
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cena:
218,07 |
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Biophysical Labeling Methods in Molecular Biology
ISBN: 9780521431323 / Angielski / Twarda / 320 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This monograph describes the theoretical bases and experimental prerequisites for methods such as spin fluorescence, triplet, Mossbauer, photochromic and electron-density labeling, including the procedures used to obtain specifically modified proteins, enzymes, biomembranes, nucleic acids, and other biological molecules. The fundamentals of the physical theory behind each technique is explained and details are given of how to interpret the experimental data obtained. Special sections deal with critical reviews of recent data on the structure, molecular dynamics and conformational transitions...
This monograph describes the theoretical bases and experimental prerequisites for methods such as spin fluorescence, triplet, Mossbauer, photochromic ...
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cena:
523,97 |
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Progress in Medicinal Chemistry
ISBN: 9780444829092 / Angielski Termin realizacji zamówienia: ok. 5-8 dni roboczych. Eminent scientists at the cutting edge of pharmacology and medicinal chemistry research provide us with yet another excellent addition to this famous series. The focus on bacterial resistance mechanisms serves to highlight an important area of unmet medical need requiring the attention of medicinal chemists. Five topical subjects are reviewed: the biosynthesis, metabolism and function of Vitamin D3 and the potential application of its analogues in bone disorders and immune-related diseases; the therapeutic potential of neurokinin antagonists; opioid receptor antagonists; the mechanisms of...
Eminent scientists at the cutting edge of pharmacology and medicinal chemistry research provide us with yet another excellent addition to this famous ...
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cena:
620,95 |
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Clinical Proteomics: Methods and Protocols
ISBN: 9781588298379 / Angielski / Twarda / 408 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In this book, a select group of researchers has contributed their state-of-the-art methodologies on protein profiling and identification of disease biomarkers in tissues, microdissected cells and body fluids. The book integrates biochemistry, pathology, analytical technology, bioinformatics, and proteome informatics. Experimental approaches are thoroughly detailed and explained through a step-by-step instructional format that ensures successful results. In this book, a select group of researchers has contributed their state-of-the-art methodologies on protein profiling and identification of disease... |
cena:
407,25 |
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Focus on Protein Research
ISBN: 9781590339688 / Angielski / Twarda / 245 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Protein research is a frontier field in science. Proteins are widely distributed in plants and animals and are the principal constituents of the protoplasm of all cells, and consist essentially of combinations of a-amino acids in peptide linkages. Twenty different amino acids are commonly found in proteins, and serve as enzymes, structural elements, hormones, immunoglobulins, etc., and are involved throughout the body, and in photosynthesis. This new book gathers new leading-edge research from throughout the world in this exciting and exploding field of research.
Protein research is a frontier field in science. Proteins are widely distributed in plants and animals and are the principal constituents of the proto...
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cena:
596,05 |
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Trends in Cholesterol Research
ISBN: 9781594543784 / Angielski / Twarda / 171 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Cholesterol is a soft, waxy substance found among the lipids (fats) in the bloodstream and in all the body's cells. It's an important part of a healthy body because it's used to form cell membranes, some hormones and is needed for other functions. But a hi
Cholesterol is a soft, waxy substance found among the lipids (fats) in the bloodstream and in all the body's cells. It's an important part of a health...
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cena:
1033,20 |