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Calcium-Binding Protein Protocols: Volume 2: Methods and Techniques
ISBN: 9780896036895 / Angielski / Twarda / 415 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Calcium plays an important role in a wide variety of biological processes. This divalent metal ion can bind to a large number of proteins; by doing so it modifies their biological activity or their stability. Because of its distinct che- cal properties calcium is uniquely suited to act as an on off switch or as a light dimmer of biological activities. The two books entitled Calcium-Binding Protein Protocols (Volumes I and II) focus on modern experimental analyses and methodologies for the study of calcium-binding proteins. Both extracel- lar and intracellular calcium-binding proteins are...
Calcium plays an important role in a wide variety of biological processes. This divalent metal ion can bind to a large number of proteins; by doing so...
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cena:
402,53 |
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Sparking Signals: Kinases as Molecular Signaltransducers and Pharmacological Drug Targets in Inflammation
ISBN: 9783540735007 / Angielski / Twarda / 187 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Protein phosphorylation is an essential post-translational modification that modulates cell cell communication. Substrate phosphorylation by protein kinases controls intracellular signal transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors... Protein phosphorylation is an essential post-translational modification that modulates cell cell communication. Substrate phosphorylation by protei... |
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402,53 |
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Signaling Mechanisms of Oxygen and Nitrogen Free Radicals
ISBN: 9781420073744 / Angielski / Twarda / 220 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Once the existence of free radicals was proven, an avalanche of studies on free radical-mediated biological processes ensued. The study of reactive oxygen and nitrogen species (ROS and RNS) is center stage in biological free radical investigations. Written by a biochemist, Signaling Mechanisms of Oxygen and Nitrogen Free Radicals discusses the regulatory functions of ROS and RNS in physiological and pathophysiological states. An exploration of the main questions of signaling mechanisms of reactive oxygen and nitrogen species in enzymatic processes, this book... Once the existence of free radicals was proven, an avalanche of studies on free radical-mediated biological processes ensued. The study of reactive... |
cena:
930,57 |
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Class 1 Oxidoreductases IV: EC 1.1.2 - 1.1.99
ISBN: 9783540222453 / Angielski / Twarda / 424 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized - and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement... The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized - and here is the second, updated edit... |
cena:
1207,67 |
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Small Gtpases in Disease, Part B: Volume 439
ISBN: 9780123743114 / Angielski / Twarda / 559 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The critically acclaimed laboratory standard for more than 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today-truly an essential publication for researchers in all fields of life sciences. Methods in Enzymology is now available online at ScienceDirect - full-text online of volume 1... The critically acclaimed laboratory standard for more than 40 years, Methods in Enzymology is one of the most highly respected publications ... |
cena:
764,04 |
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Copper Amine Oxidases: Structures, Catalytic Mechanisms and Role in Pathophysiology
ISBN: 9781420076806 / Angielski / Twarda / 374 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Although the amount of research on copper amine oxidases has grown rapidly and substantially in the past decade, the field unfortunately suffers from lack of cohesion and significant confusion surrounds aspects as simple as confirmation of enzyme identities. This book describes the structure of the enzymes, the role of copper, and of the unusual cofactor 6-hydroxydopa quinine derived from a posttranslational modification of a tyrosine residue. It also covers the differences of between AOs from bacteria, plants, and mammals. Finally, the text examines the importance of this ubiquitous class... Although the amount of research on copper amine oxidases has grown rapidly and substantially in the past decade, the field unfortunately suffers fr... |
cena:
979,55 |
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Bioscience at the Physical Science Frontier: Proceedings of a Foundation Symposium on the 150th Anniversary of Alfred Nobel's Birth
ISBN: 9780896031319 / Angielski / Twarda / 270 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since early Greek and Roman times, atoms were assumed-after un dergoing their various interactions-to take on the stable configurations of either the living or the inanimate world. This simple and unitary theory has evolved markedly, even while maintaining its validity over several centuries of vicissitudes, and in essence constitutes the first ex ample of a synthesis between the physical and the life sciences. In modern times, a similar relationship between the structure of various macromolecules and the function of living cells has also emerged as one of the most striking findings of those...
Since early Greek and Roman times, atoms were assumed-after un dergoing their various interactions-to take on the stable configurations of either the ...
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cena:
603,81 |
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Antibacterial Peptide Protocols
ISBN: 9780896034082 / Angielski / Twarda / 259 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. As this book. Antibacterial Peptide Protocols, will attest, my enthusi asm for the field of antibacterial peptides is based on a conviction (and I am unashamed to say, prejudice) that these substances are in essence antibiotics produced by the host that then participate in host defense against infectious agents. Because of their capacity to exert antibiotic-like action against patho genic microorganisms (bacteria, fungi, parasites, and viruses), there is reason to believe that these agents will soon be used clinically to treat infectious diseases. In fact, in recent years, biotechnology...
As this book. Antibacterial Peptide Protocols, will attest, my enthusi asm for the field of antibacterial peptides is based on a conviction (and I am ...
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cena:
603,81 |
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Gene Transfer and Expression in Mammalian Cells: Volume 38
ISBN: 9780444513717 / Angielski / Twarda / 680 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The production of proteins in mammalian cells is an important tool in numerous scientific and commercial areas. For example, proteins for human therapy, vaccination or diagnostic applications are typically produced in mammalian cells. Gene cloning, protein engineering, biochemical and biophysical characterization of proteins also require the use of gene expression in mammalian cells. Other applications in widespread use involve screening of libraries of chemical compounds in drug discovery, and the development of cell-based biosensors. This book presents a state-of-the-art comprehensive...
The production of proteins in mammalian cells is an important tool in numerous scientific and commercial areas. For example, proteins for human therap...
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cena:
1199,94 |
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Artificial Nucleases
ISBN: 9783540201120 / Angielski / Twarda / 292 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the immediate and very important applications they can find in the emerging fields of biotechnology and pharmacology. There are essentially two classes of these agents - nucleases that occur naturally inside cells and synthetically produced artificial nucleases. The first class includes protein enzyme nucle ases and catalytic RNA structured ribozymes that perform cleavage of the phosphodiester bonds in nucleic acids according to a hydrolytic pathway...
The development of agents capable of cleaving RNA and DNA has attracted considerable attention from researchers in the last few years, because of the ...
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cena:
1207,67 |
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Biomedical Image Registration: Second International Workshop, WBIR 2003, Philadelphia, PA, USA, June 23-24, 2003, Revised Papers
ISBN: 9783540203438 / Angielski / Miękka / 410 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The 2nd International Workshop on Biomedical Image Registration (WBIR) was held June 23-24, 2003, at the University of Pennsylvania, Philadelphia. Following the success of the ?rst workshop in Bled, Slovenia, this meeting aimed to once again bring together leading researchers in the area of biomedical image registration to present and discuss recent developments in the ?eld. Thetheory, implementationandapplicationofimageregistrationinmedicine have become major themes in nearly every scienti?c forum dedicated to image processingandanalysis. Thisintenseinterestre?ectsthe?eld'simportantrolein...
The 2nd International Workshop on Biomedical Image Registration (WBIR) was held June 23-24, 2003, at the University of Pennsylvania, Philadelphia. Fol...
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cena:
201,24 |
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Metabolic Engineering
ISBN: 9783540418481 / Angielski / Twarda / 184 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology, developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae...
Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of ...
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cena:
805,10 |
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Prostaglandins, Leukotrienes, Lipoxins, and Paf: Mechanism of Action, Molecular Biology, and Clinical Applications
ISBN: 9780306440557 / Angielski / Twarda / 461 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The field of eicosanoid metabolism and function continues to grow. Synthesis of the prostaglandins from essential fatty acids was first described by Bergstrom and Sarnuelsson in 1964. The thromboxanes were discovered in 1975, the prostacyclins, by Moncada and Vane, in 1976, and the leukotrienes by Samuelsson in 1979. A new class of biologically active arachidonic acid metabolites named lipoxins was announced by Bengt Samuelsson in May 1984. Since that time major advances have been made in the molecular biology of the eicosanoids including the cloning of prostaglandin synthases and 5, 12, and...
The field of eicosanoid metabolism and function continues to grow. Synthesis of the prostaglandins from essential fatty acids was first described by B...
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cena:
805,10 |
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Molecular Modeling of Proteins
ISBN: 9781588298645 / Angielski / Twarda / 390 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Molecular modeling has undergone a remarkable transformation in the last 20 years. This book provides thorough introductions and a compilation of step-by-step methods applicable to problems faced by non-specialists especially those new to the software packages used in molecular modeling. Tips on troubleshooting and avoiding common pitfalls are included in the book, along with chapters covering a wide range of subjects. Links to downloadable software are also provided."
Molecular modeling has undergone a remarkable transformation in the last 20 years. This book provides thorough introductions and a compilation of s... |
cena:
603,81 |
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Macromolecular Medical Biochem
ISBN: 9780521278287 / Angielski / Miękka / 280 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This text aims to bring to the attention of undergraduate students of biochemistry the many exciting developments in cell and molecular biology in recent years and their important implications for the practice of medicine. Emphasis is placed on such topics as membrane structure and function and hormone action and secretion, where current knowledge of macromolecular and cellular structure and function will contribute most to understanding the underlying pathology of common multifactorial diseases. The book also outlines the basic features of recombinant DNA techniques and their probable impact...
This text aims to bring to the attention of undergraduate students of biochemistry the many exciting developments in cell and molecular biology in rec...
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cena:
284,70 |
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Biological Magnetic Resonance: In Vivo Carbon-13 NMR
ISBN: 9780306458866 / Angielski / Twarda / 255 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume constitutes a compilation of the latest experiments and theories on a rapidly evolving and maturing field in MRI/MRS, which is the use of the stable isotope 13-C. The 13-C is used to probe the chemistry, mechanism, and function in living systems.
All the chapters are written by experts in the field who discuss topics such as Tracer Theory and the Suitability of 13-C NMR', Applications of 13-C to Studies of Human Brain Metabolism', etc. This volume constitutes a compilation of the latest experiments and theories on a rapidly evolving and maturing field in MRI/MRS, which is the use of ...
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cena:
805,10 |
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Progress in Medicinal Chemistry: Volume 46
ISBN: 9780444530189 / Angielski / Twarda / 407 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Appropriate selection of biochemical targets is one of the most important drivers of cost effectiveness in the discovery of new medicines. Despite the many advances in genetics, genomics and systems biology, 'validation' of a target is not achieved until therapeutic efficacy is demonstrated by a drug candidate. Volume 46 of this series reviews the medicinal chemistry aimed at six diverse targets from which important new medicines are emerging:
* HIV integrase (discovery of the first-in-class inhibitor drug raltegravir) * 11-beta-Hydroxysteroid dehydrogenase (new approach to... Appropriate selection of biochemical targets is one of the most important drivers of cost effectiveness in the discovery of new medicines. Despite the...
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cena:
685,68 |
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Electron Paramagnetic Resonance in Biochemistry and Medicine
ISBN: 9780306465314 / Angielski / Twarda / 268 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Electron Paramagnetic Resonance (EPR) spectroscopy - also sometimes termed Electron Spin Resonance spectroscopy - has manifold potential uses in biochemistry and medicine. The paramount importance of EPR spectroscopy applied to biological tissues and fluids is that it identifies the changes in redox processes that contribute to disease.
EPR spectroscopy has come a long way from its original use to detect malignant tumors. For example, the development and later refinement of methods of low-temperature registration of biological tissues widened the scope of EPR spectroscopy. Innovations... Electron Paramagnetic Resonance (EPR) spectroscopy - also sometimes termed Electron Spin Resonance spectroscopy - has manifold potential uses in bioch...
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cena:
402,53 |
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Fundamentals of Tissue Engineering and Regenerative Medicine
ISBN: 9783540777540 / Angielski / Twarda / 1049 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. "Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are... "Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regen... |
cena:
1328,44 |
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Human Blood Plasma Proteins: Structure and Function
ISBN: 9780470016749 / Angielski / Twarda / 538 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include:
Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and functio...
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cena:
724,62 |
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