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Extracellular ATP and Adenosine as Regulators of Endothelial Cell Function: Implications for Health and Disease
ISBN: 9789048134342 / Angielski / Twarda / 236 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Extracellular purines and pyrimidines (ATP, ADP, UTP and adenosine) are released into the extracellular milieu in response to a variety of stress conditions and act as important regulators of vascular homeostasis. This new book is uniquely focused on the signaling actions of extracellular purines in endothelial cells and the crucial role of extracellular purines in regulation of angiogenesis, vascular tone, cell permeability, wound healing, inflammation and cell-to-cell communication. This book examines the responses of endothelial cells, originating from various tissues (such as cornea,...
Extracellular purines and pyrimidines (ATP, ADP, UTP and adenosine) are released into the extracellular milieu in response to a variety of stress cond...
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cena:
603,81 |
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Heat Shock Proteins and Whole Body Physiology
ISBN: 9789048133802 / Angielski / Twarda / 430 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Heat Shock Proteins and Whole Body Physiology is an exciting new book in the Heat Shock Proteins series which provides the most up-to-date review on novel mechanisms insights into the important role played by heat shock proteins in human physiology. Written by leaders in the field of heat shock protein exercise physiology, neuroscience and aging, the chapters systematically and in a step wise fashion takes the reader through the fascinating mechanisms by which heat shock proteins modulate human disease and pathophysiology and provides answers as to its biological significance to the host.... Heat Shock Proteins and Whole Body Physiology is an exciting new book in the Heat Shock Proteins series which provides the most up-to-date review o... |
cena:
805,10 |
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Nutritional Biochemistry of the Vitamins
ISBN: 9780521122214 / Angielski / Miękka / 516 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. An authoritative and comprehensive review of current research in vitamin nutrition, deficiency and metabolism.
An authoritative and comprehensive review of current research in vitamin nutrition, deficiency and metabolism.
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cena:
348,51 |
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Peptidomics: Methods and Protocols
ISBN: 9781607615347 / Angielski / Twarda / 395 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Despite being known and studied for years, peptides have never before attracted enough attention to necessitate the invention of the term "peptidomics" in order to specify the study of the complement of peptides from a cell, organelle, tissue or organism. In Peptidomics: Methods and Protocols, expert researchers present a comprehensive range of analytical techniques for the analysis of the peptide contents of complex biological samples with an emphasis often on higher throughput techniques, suitable for the analysis of large numbers of peptides typically present in the peptidomes.... Despite being known and studied for years, peptides have never before attracted enough attention to necessitate the invention of the term "peptidom... |
cena:
603,81 |
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Noninvasive Cerebrovascular Diagnosis
ISBN: 9781848829565 / Angielski / Miękka / 150 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. "Noninvasive Cerebrovascular Diagnosis" is the newest definitive text on the current techniques used in assessing vascular disorders. Readers will receive authoritative information and will be guided through the establishment and accreditation of a vascular laboratory and introduced to the physics of diagnostic testing. Chapters, written by selected experts, comprehensively explain the use of ultrasound in diagnosing cerebrovascular, renovascular, visceral ischemia and peripheral arterial disease as well as venous disorders and deep abdominal vascular conditions. Noninvasive Vascular... "Noninvasive Cerebrovascular Diagnosis" is the newest definitive text on the current techniques used in assessing vascular disorders. Readers will ... |
cena:
201,24 |
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Cancer Therapeutic Targets
ISBN: 9781441907165 / Angielski / Twarda / 1105 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In the past decade, we have experienced an explosion of new information about cancer therapeutic targets. Many of the targets have been validated by the discovery and approval of new medicines which have been approved for the treatment of cancer. On the heels of these successes, innumerable new targets and new potential therapeutics are being developed by many different groups including government agencies, pharmaceutical companies, biotechnology companies, academic institutions, and individual investigators. Understanding the expanding -universe- of cancer therapies is therefore becoming... In the past decade, we have experienced an explosion of new information about cancer therapeutic targets. Many of the targets have been validated b... |
cena:
3623,09 |
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Bone and Development
ISBN: 9781848828216 / Angielski / Twarda / 305 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book, Vol. 6 in the series Topics in Bone Biology, deals with bone develop ment from growth to mineralization. Understanding tissue dev- opment involves combining embryological and histological information with the increasing knowledge from molecular and genetic studies. In each developmental stage, some genes are expressed and others silenced. Disease, especially disease progression, also is characterized by changes in gene expression that then are transmitted to daughter cells. In both situations, the choreography of gene expression and partial or complete silencing often are the...
This book, Vol. 6 in the series Topics in Bone Biology, deals with bone develop ment from growth to mineralization. Understanding tissue dev- opment i...
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cena:
603,81 |
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Handbook of Aqueous Solubility Data
ISBN: 9781439802458 / Angielski / Twarda / 1620 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Over the years, researchers have reported solubility data in the chemical, pharmaceutical, engineering, and environmental literature for several thousand organic compounds. Until the first publication of the Handbook of Aqueous Solubility Data, this information had been scattered throughout numerous sources. Now newly revised, the second edition of this landmark volume continues the tradition of providing an extensive compilation of published aqueous solubility data for a wide variety of organic nonelectrolytes and unionized weak electrolytes. Adds data... Over the years, researchers have reported solubility data in the chemical, pharmaceutical, engineering, and environmental literature for several th... |
cena:
2301,94 |
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The Carbonic Anhydrases: New Horizons
ISBN: 9783764356705 / Angielski / Twarda / 619 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of profound physiological importance, which plays essential roles in respiration, acid-base homeostasis, bone resorption, calcification, photosynthesis, several biosynthetic pathways and a variety of processes involving ion, gas and fluid transfer. This enzyme, which is present in at least three gene families (a, ss, ?), has found favour as a model for the study of evolution of gene families and for site-directed mutagenesis in structure/function relationships, for protein folding and for transgenic and gene target studies. Since the...
Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of profound physiological importance, which plays essential roles in respiration, acid-base h...
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cena:
1207,67 |
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Recent Advances in Glucocorticoid Receptor Action
ISBN: 9783540432296 / Angielski / Twarda / 380 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Since 1948, hydrocortisone (cortisol), the principal glucocorticoid (GC) of the human adrenal cortex has been successfully used at phar macological concentrations for the suppression of clinical manifesta tions of rheumatoid arthritis. Numerous compounds with GC activity have also been developed and used. Fifty years after their initial clinical use, GCs are still the most im portant and frequently prescribed class of anti-inflammatory drugs for various inflammatory disorders. They are administered either orally, parenterally (intravenous, intramuscular, intrathecal), or topically (cu...
Since 1948, hydrocortisone (cortisol), the principal glucocorticoid (GC) of the human adrenal cortex has been successfully used at phar macological co...
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cena:
1053,40 |
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Focus on Homocysteine and the Vitamins: Involved in Its Metabolism
ISBN: 9782287597121 / Angielski / Miękka / 262 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. During the last 10-12 years, the research on homocysteine has become very active. About 1500 of articles are now published each year on homocysteine and the vitamins involved in its metabolism. A disturbed homocysteine metabolism can be an underlying factor for pregnancy complications and fetal malformations, cardiovascular disease, dementia, psychiatric and neurologic disorders and possibly carcinogenesis. A disturbed homocysteine metabolism can in most cases be normalised by treatment with folate and/or vitamines B12 and B6. Many of these findings therefore directly concern most...
During the last 10-12 years, the research on homocysteine has become very active. About 1500 of articles are now published each year on homocysteine ...
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cena:
402,53 |
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Fundamentals of Microfluidics and Lab on a Chip for Biological Analysis and Discovery
ISBN: 9781439818558 / Angielski / Miękka / 418 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This comprehensive textbook presents the fundamentals of microfluidic lab-on-a-chip systems and provides an overview of the available technology, its limitations, and its breakthroughs. It emphasizes analytical applications of microfluidic technology and provides in-depth coverage of micromachining, nucleic acids, and mass spectrometry. It also covers more recent advances in microdrops and nanoparticles. Ideal for students, the text includes historical background, expanded problem sets in each chapter, a comprehensive glossary, a complete index, and extensive references. A solutions manual... This comprehensive textbook presents the fundamentals of microfluidic lab-on-a-chip systems and provides an overview of the available technology, i... |
cena:
367,28 |
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A Molecular and Cellular View of Protein Kinase Ck2
ISBN: 9780792382089 / Angielski / Twarda / 239 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. It is now generally recognized that protein kinase signaling is involved in virtually every aspect of cell function, including growth and proliferation. The field of protein phosphorylation, including the enzymes involved in this post-translational modification, continues to advance at a fascinating pace.
Since the first international meeting on this topic, held in Heidelberg in 1994, several new avenues of CK2 research have emerged despite persistent deficiencies in our understanding of the regulation of its activity. Among the significant new directions are studies related to the... It is now generally recognized that protein kinase signaling is involved in virtually every aspect of cell function, including growth and proliferatio...
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cena:
805,10 |
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Control of Gene Expression by Catecholamines and the Renin-Angiotensin System
ISBN: 9780792379812 / Angielski / Twarda / 239 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The special issue of Molecular and Cellular Biochemistry focuses on Control of Gene Expression by Catecholamines and the Renin-Angiotensin System' in health and disease. In recent years, great progress has been made in the understanding of catecholamine and angiotensin II modulated gene expression. There is also increasing evidence that catecholamine and angiotensin II induced cellular injury not solely arises from classical pathways but also from a perturbed gene expression.
Taking into account that catecholamines and angiotensin II are vital for a balanced gene expression of... The special issue of Molecular and Cellular Biochemistry focuses on Control of Gene Expression by Catecholamines and the Renin-Angiotensin Sy...
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cena:
603,81 |
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Cardiac Metabolism in Health and Disease
ISBN: 9780792381044 / Angielski / Twarda / 202 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This special issue of Molecular and Cellular Biochemistry contains original research papers as well as invited reviews focused in the field of cardiac metabolism and its regulation under normal and disease conditions. These papers cover many areas under intensive and rapid development such as the regulation of fatty acid oxidation in the heart, the role of cardiac glycogen during ischemia, the role of CPT I isoenzymes, the pathophysiology of diabetic cardiomyopathy, cardiac protection through regulation of energy production, the role of fatty acid binding protein under normal and...
This special issue of Molecular and Cellular Biochemistry contains original research papers as well as invited reviews focused in the field o...
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cena:
805,10 |
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The Cellular Basis of Cardiovascular Function in Health and Disease
ISBN: 9780792399742 / Angielski / Twarda / 353 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This special issue of Molecular and Cellular Biochemistry our their mentor. The ex-students and trainees came from contains original research articles and review papers which all over Canada, the United States, Japan, Slovakia, Ger were invitedfrom the participants ofa recent meeting organ many, the Czech Republic, Estoniaand the Netherlands. The izedto honourthe 60th birthdayofNaranjan S. Dhalla, Ph.D., meeting wasjudged to be an overwhelming success in terms M.D. (Hon.). The meeting, organized by Drs. Morris Karma ofthe scientific content as well as collaborative interactions zyn (London),...
This special issue of Molecular and Cellular Biochemistry our their mentor. The ex-students and trainees came from contains original research articles...
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cena:
1207,67 |
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Vanadium Compounds: Biochemical and Therapeutic Applications
ISBN: 9780792337621 / Angielski / Twarda / 246 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In vitro and animal studies show that vanadate and other Because most cellular components contain hydroxyl and/or vanadium compounds increase glucose transport activity and phosphate groups, vanadate reacts as shown in eq. 1, and 2 normalize glucose metabolism 1-5]. Furthermore, these with a variety of metabolites. For example, the reaction of insulin-mimetic compounds can be administered orally. Vana vanadate with the 2'-hydroxyl group of the cofactor NAD date enhances the phosphoprotein formation which is attrib generates an NADP analog, NADV (path b) 22]. NADV is uted to either the...
In vitro and animal studies show that vanadate and other Because most cellular components contain hydroxyl and/or vanadium compounds increase glucose ...
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cena:
402,53 |
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Creatine:: From Basic Science to Clinical Application
ISBN: 9780792361183 / Angielski / Twarda / 119 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume, based on the International Congress Creatine: From Basic Science to Clinical Application, held in Milan on June 4, 1999, outlines the physiological role of creatine in the human body as well as its possible role in different pathological conditions. Creatine is already used as a dietary supplement to augment muscle performance in healthy individuals and inpatients with immobilizing diseases, such as complex fractures. There is also an increasing interest in its administration in a growing number of clinical conditions. A specific deficit of endogenous synthesis of creatine which...
This volume, based on the International Congress Creatine: From Basic Science to Clinical Application, held in Milan on June 4, 1999, outlines the phy...
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cena:
407,16 |
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Enzymology and Molecular Biology of Carbonyl Metabolism 7
ISBN: 9780306461132 / Angielski / Twarda / 555 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This volume contains information on aldehyde dehydrogenase, alcohol dehydrogenase, short- and medium-chain dehydrogenase, and reductases. Sixty-nine contributions provide a wide variety of information on enzymology, molecular biology, and metabolic aspects of these carbonyl metabolizing oxido-reductases. Much new information is provided, including previously unreported three-dimensional structures of enzymes and new aspects of gene regulation, along with sequence alignments, metabolism and enzyme mechanisms.
This volume contains information on aldehyde dehydrogenase, alcohol dehydrogenase, short- and medium-chain dehydrogenase, and reductases. Sixty-nine c...
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cena:
480,69 |
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Aspartic Proteinases: Retroviral and Cellular Enzymes
ISBN: 9780306458095 / Angielski / Twarda / 499 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The VIIth International Conference on Aspartic Proteinases was held in Banff, Alberta, Canada, from October 22 to 27, 1996. The venue was the Banff Centre in the Canadian Rockies, a setting well known worldwide for the scenic beauty and mountain grandeur. It was perhaps presumptuous of the organizers to call this the seventh Aspartic Proteinase Conference but it was felt that the meeting in 1982, organized by Tom Blundell and John Kay, was of an international stature and covered topics sufficiently broad to constitute a conference. Thus, there is a discontinuity in that the Gifu Conference...
The VIIth International Conference on Aspartic Proteinases was held in Banff, Alberta, Canada, from October 22 to 27, 1996. The venue was the Banff Ce...
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cena:
603,81 |