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Vitamins and Hormones: Volume 65
ISBN: 9780127098654 / Angielski / Twarda / 386 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists,...
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the ...
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710,17 |
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The Role of Complexin in Regulated Exocytosis
ISBN: 9783639014396 / Angielski / Miękka / 132 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This work has studied the role of complexin in regulated exocytosis, a key mechanism underlies hormone and neurotransmitter release and understanding of which will help to design therapeutic interventions in a lot of neuronal diseases or endocrine diseases. The work here systematically dissects the vesicle stages leading up to exocytosis using a knockout-rescue strategy in a mammalian model system. The work shows that adrenal chromaffin cells from CPX II knockout mice exhibit a markedly diminished readily releasable vesicle pool, while showing no change in the kinetics of fusion pore dilation...
This work has studied the role of complexin in regulated exocytosis, a key mechanism underlies hormone and neurotransmitter release and understanding ...
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263,91 |
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The Ubiquitin System in Health and Disease
ISBN: 9783540851066 / Angielski / Twarda / 191 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The ubiquitin system has two major functions in eukaryotic cells: it r- ulates protein degradation, which is essential for normal cellular fu- tion and for the removal of potentially harmful, damaged, or misfolded proteins, and it controls protein activity by regulating protein-protein interactions and subcellullar localization. The ubiquitin system is thus involved in processes as diverse as cell cycle progression, signal tra- duction, gene transcription, and DNA repair. Not surprisingly, defects in the ubiquitin system have been linked with numerous diseases such as cancer, in?ammation,...
The ubiquitin system has two major functions in eukaryotic cells: it r- ulates protein degradation, which is essential for normal cellular fu- tion an...
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603,81 |
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Class 2 Transferases: EC 2.1-2.7.10
ISBN: 9783540856962 / Angielski / Twarda / 565 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized - and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement... The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized - and here is the second, updated edit... |
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1207,67 |
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Handbook of Essential Fatty Acid Biology: Biochemistry, Physiology, and Behavioral Neurobiology
ISBN: 9780896033658 / Angielski / Twarda / 470 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Internationally eminent scientists illuminate the most important scientific aspects of essential fatty acids (EFAs)-from their biochemistry to their physiological consequences in both health and illness. The distinguished contributors integrate a wide range of topics, including the basic biochemistry of EFAs and lipid metabolism, the role of EFAs in the neuronal membrane, the effects of EFAs and lipids in various diseases, and the effects of normal levels and EFA deficiencies on cognition and behavior. The book's consolidation of our knowledge of the biology and metabolism of the EFAs lays...
Internationally eminent scientists illuminate the most important scientific aspects of essential fatty acids (EFAs)-from their biochemistry to their p...
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603,81 |
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Clinical Applications of Capillary Electrophoresis
ISBN: 9780896036390 / Angielski / Twarda / 212 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The term "electrophoresis" was first used by Michaelis in 1909, to - scribe the migration of colloids in an electric field. The first practical elect- phoresis method was described by Tiselius in 1937. He used a U-tube filled with buffer layered on top of sample; migration could be monitored using Schlieren optics. In zone electrophoresis, the U-tube was replaced by paper, a support material employed simply to prevent or minimize diffusion of ions, so that ions applied in a narrow strip to the paper will separate and remain as relatively discrete zones. Paper was superceded by a variety of...
The term "electrophoresis" was first used by Michaelis in 1909, to - scribe the migration of colloids in an electric field. The first practical elect-...
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402,53 |
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Calcium-Binding Protein Protocols: Volume 1: Reviews and Case Studies
ISBN: 9780896036888 / Angielski / Twarda / 340 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Calcium plays an important role in a wide variety of biological processes. This divalent metal ion can bind to a large number of proteins; by doing so it modifies their biological activity or their stability. Because of its distinct che- cal properties calcium is uniquely suited to act as an on off switch or as a light dimmer of biological activities. The two books entitled Calcium-Binding Protein Protocols (Volumes I and II) focus on modern experimental analyses and methodologies for the study of calcium-binding proteins. Both extracel- lar and intracellular calcium-binding proteins are...
Calcium plays an important role in a wide variety of biological processes. This divalent metal ion can bind to a large number of proteins; by doing so...
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402,53 |
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Biotechnology for Fuels and Chemicals: The Twenty-Third Symposium
ISBN: 9781588291714 / Angielski / Twarda / 1227 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. With the Twenty-Third Symposium, we sustained the tradition of providing an informal, congenial atmosphere that our participants find conducive to pursuing technical discussion of program topics. The techni cal program consisted of six sessions with 38 oral presentations, a roundtable forum, two special topic discussions and a poster session con sisting of 230 posters. A special luncheon talk on "Natural Capitalism" by Karl Rabago of the Rocky Mountain Institute was particularly enlightening. More infor mation on these provocative approaches to resources and societal needs can be found at...
With the Twenty-Third Symposium, we sustained the tradition of providing an informal, congenial atmosphere that our participants find conducive to pur...
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603,81 |
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Proteins
ISBN: 9780896030626 / Angielski / Twarda / 365 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In recent years there has been a tremendous increase in our understanding of the functioning of the cell at the molecular level. This has been achieved in the main by the invention and development of new methodology, parti- larly in that area generally referred to as "'genetic en- neering." While this revolution has been taking place in the field of nucleic acids research, the protein chemist has at the same time developed fresh methodology to keep pace with the requirements of present day molecular bi- ogy. Today's molecular biologist can no longer be content with being an expert in one...
In recent years there has been a tremendous increase in our understanding of the functioning of the cell at the molecular level. This has been achieve...
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402,53 |
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Nucleic Acids
ISBN: 9780896030640 / Angielski / Twarda / 375 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In recent years there has been a tremendous increase in our understanding of the functioning of the cell at the molecular level. This has been achieved in the main by the invention and development of new methodology, parti- larly in that area generally referred to as "genetic en- neering." While this revolution has been taking place in the field of nucleic acids research, the protein chemist has at the same time developed fresh methodology to keep pace with the requirements of present day molecular bi- ogy. Today's molecular biologist can no longer be content with being an expert in one...
In recent years there has been a tremendous increase in our understanding of the functioning of the cell at the molecular level. This has been achieve...
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402,53 |
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Biology of Copper Complexes
ISBN: 9780896031234 / Angielski / Twarda / 598 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. In 1928, it was discovered that copper was essential for normal human metabolism. Ten years later, 1938, it was observed that patients with rheumatoid arthritis had a higher than normal serum copper concentration, which returned to normal wi th remission of this disease. Thirteen years later, it was found that copper complexes were effective in treating arthritic diseaseS. The first report that copper complexes had antiinflammatory activity in an animal model of in- flammation appeared twenty-two years after the discovery of essen- tiality. In 1976, it was suggested that the active forms of...
In 1928, it was discovered that copper was essential for normal human metabolism. Ten years later, 1938, it was observed that patients with rheumatoid...
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805,10 |
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Trace Elements, Micronutrients, and Free Radicals
ISBN: 9780896031883 / Angielski / Twarda / 231 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Itisonlyrecently thatthe naturaloccurrenceoffree radicalsin biological tissue has become widely accepted, and that the suspi- cion with which biologists previously viewed the free radicals of radiationchemistryhas beenplacedin a broaderperspective. Now, oxygen-derived free radicals are considered respectable biochemi- cal intermediates, given always the caveat that unwanted tissue damage may arise if these active species are produced in such abundance that they overwhelm the natural antioxidant and free- radical defense mechanisms, or if these systems have become hypoeffective. Many factors,...
Itisonlyrecently thatthe naturaloccurrenceoffree radicalsin biological tissue has become widely accepted, and that the suspi- cion with which biologis...
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603,81 |
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Nuclear Analytical Methods in the Life Sciences
ISBN: 9780896032026 / Angielski / Twarda / 776 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The 1989 International Conference on Nuclear Analytical Methods in theUfe Scienceswas a continuationofa seriesofconfer encesheldbytheInternationalAtomicEnergyAgency. Thefirsttook placeinAmsterdamin 1967, thesecondin Bledin 1972, andthethird inViennain 1978. Theaimoftheseconferenceshasbeentostimulate discussions between scientists who are working as biologists, envi ronmentalists, and physicians, and those who are working on the advancementofnuclear analytical techniques. The 1989 Conference was held at the National Institute of Standards and Technology (NIST, formerly the National Bureau of...
The 1989 International Conference on Nuclear Analytical Methods in theUfe Scienceswas a continuationofa seriesofconfer encesheldbytheInternationalAtom...
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805,10 |
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Regulatory Mechanisms of Intracellular Membrane Transport
ISBN: 9783540223023 / Angielski / Twarda / 214 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. This book deals with the molecular mechanisms of membrane trafficking, a central eukaryotic cell biological process. In the post-genomic era many essential molecules involved in intracellular membrane/protein transport are emerging. A huge task now is to compile the molecular networks that govern these processes. Understanding of regulatory processes and participating molecules are likely to reveal global cellular regulatory circuits that couple membrane trafficking with other cellular functions. Such cell biological features are only starting to emerge. This book puts special emphasis on...
This book deals with the molecular mechanisms of membrane trafficking, a central eukaryotic cell biological process. In the post-genomic era many esse...
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603,81 |
![Biocombinatorial Approaches for Drug Finding W. Wohlleben T. Spellig B. M]ller-Tiemann 9783540220923 Springer](/9783540220923_biocombinatorial_approaches_for_drug_finding.jpg "Biocombinatorial Approaches for Drug Finding") |
Biocombinatorial Approaches for Drug Finding
ISBN: 9783540220923 / Angielski / Twarda / 284 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Genome- and proteome-based research is generating a significant increase in the number of available drug targets. Correspondingly there is an increasing need for novel, diverse compounds, particularly based on natural compounds, as screening resource. The purpose of the Ernst Schering Research Foundation Workshop 51 was to provide a forum for an open exchange on perspectives and limitations of biocombinatorial synthesis and the significance of this technology for future drug discovery in light of this challenge. Experts from academia and industry provided contributions covering:... Genome- and proteome-based research is generating a significant increase in the number of available drug targets. Correspondingly there is an incre... |
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603,81 |
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Lipid Metabolism and Membrane Biogenesis
ISBN: 9783540207528 / Angielski / Twarda / 406 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. The series of review articles presented in this book summarizes the recent state of the art in lipid research in a comprehensive way. The authors provide a general overview of this field and draw the reader's attention to the most recent investigation. Biochemical, cell biological and biophysical aspects of the four major groups of lipids in eukaryotic cells, namely glycerophospholipids, sterols, sphingolipids and storage lipids, are reported and discussed. The experimental systems addressed are mammalian, plant and yeast cells as the most prominent and currently best studied systems in... The series of review articles presented in this book summarizes the recent state of the art in lipid research in a comprehensive way. The authors p... |
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1328,44 |
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Methods in Proteome and Protein Analysis
ISBN: 9783540202226 / Angielski / Twarda / 404 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. Following the succesful publication of "Proteome and Protein Analysis" in 2000, which was based on a former MPSA (Methods in Protein Structure Analysis) conference, Methods in Proteome and Protein Analysis presents the most interesting papers from the 14th MPSA meeting. Major topics include: protein and peptide sample preparation and separation; new reagent for protein sequence analysis; mass spectrometry in protein research; analysis of posttranslational modification; protein-protein interaction using MALDI-MS; manipulation of genome or functional... Following the succesful publication of "Proteome and Protein Analysis" in 2000, which was based on a former MPSA (Methods in Protein Structure Anal... |
cena:
925,87 |
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Reviews of Physiology, Biochemistry and Pharmacology
ISBN: 9783540202141 / Angielski / Twarda / 162 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. H; J. Apell: Structure -Function Relationship in P-Type ATPases - A Biophysical Approach; H. Koepsell, B. Schmitt, and V. Goboulev: Organic Cation Transporters; W.G. Wier and K.G. Morgan: Alpha 1- Adrenergic Signaling Mechanisms in Mammalian Resistance Arteries; G. Ahnert-Hilger, M. Holtje, I. Pahner, S. Winter and I.
H; J. Apell: Structure -Function Relationship in P-Type ATPases - A Biophysical Approach; H. Koepsell, B. Schmitt, and V. Goboulev: Organic Cation Tra...
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402,53 |
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Smad Signal Transduction: Smads in Proliferation, Differentiation and Disease
ISBN: 9781402045424 / Angielski / Twarda / 472 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. For the first time, world-leading experts in the area of cellular signaling have joined to the production of a book on Smad signal transduction. Smads are the principal intracellular effectors of TGF-b family members that control numerous cellular responses with critical roles in development and in tissue homeostasis. In a series of 22 cutting-edge chapters, forward looking reviews of Smads are provided that cover their discovery, evolution, role in development, mechanism of action and regulation, and how deregulation in Smad signalling contributes to human diseases. Written for an audience...
For the first time, world-leading experts in the area of cellular signaling have joined to the production of a book on Smad signal transduction. Smads...
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cena:
805,10 |
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Glycobiology and Medicine: Proceedings of the 7th Jenner Glycobiology and Medicine Symposium.
ISBN: 9780387255149 / Angielski / Twarda / 153 str. Termin realizacji zamówienia: ok. 5-8 dni roboczych. 7th Jenner Glycobiology and Medicine Symposium Sunday5 W Wednesday 8 September 2004 John S. Axford StGeorge s, University of London, UK The potential for glycobiology to improve the practice of medicine has been well recognised, which is why biannual meetings concerning the association have been taking place for the last 14 years. The science of glycobiology has matured rapidly, and with it the far reaching clinical implications are becoming understood. The next decade is going to see this ?nal frontier of science conquered. The impact this understanding of glycobiology will have upon our...
7th Jenner Glycobiology and Medicine Symposium Sunday5 W Wednesday 8 September 2004 John S. Axford StGeorge s, University of London, UK The potential ...
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cena:
805,10 |
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