In chronic parasitic infections, the interplay between the host and the parasite suggests immuno-suppressive mechanisms developed by the parasite. Echinococcus granulosus, a tiny tapeworm that among other helminthes, favors the induction of T helper type 2 responses which are less severe and less destructive than T helper type 1 responses. This study aimed at exploring the immune response generated in BALB/c mice using genetic immunization technology. Immuno-modulation by the co-delivery of different cytokine genes (IFN-γ, IL-12, IL-4) was also investigated. Immunization by antigen B or...
In chronic parasitic infections, the interplay between the host and the parasite suggests immuno-suppressive mechanisms developed by the parasite. Ech...