Inflammation is a coordinated biological response to pathogens, tissue damage, or environmental stressors, involving immune and non-immune cells, signaling pathways, and soluble mediators to restore homeostasis. Acute inflammation is protective, marked by rapid innate immune activation, leukocyte recruitment, and cytokine release (TNF- , IL-1beta, IL-6), with NF- B, MAPK, and JAK/STAT pathways driving gene transcription. Resolution occurs via pro-resolving lipid mediators, anti-inflammatory cytokines, and clearance of apoptotic cells. Dysregulation leads to chronic inflammation, driving...

Algae, including microalgae and macroalgae, are prolific producers of structurally diverse bioactive compounds with broad pharmacological activities. Their biochemical repertoire-polysaccharides, polyphenols, carotenoids, fatty acids, sterols, peptides, and pigments-confers potent antioxidant, anti-inflammatory, anticancer, immunomodulatory, antifibrotic, and antimicrobial effects. Sulfated polysaccharides like fucoidan and carrageenan modulate immune responses and fibrotic pathways, while pigments such as phycocyanin and carotenoids like astaxanthin and fucoxanthin protect against oxidative...

Nuts are nutrient-dense foods rich in unsaturated fatty acids, high-quality proteins, dietary fiber, vitamins, minerals, phytosterols, and bioactive polyphenols. Their unique composition contributes to cardiovascular protection, metabolic regulation, neuroprotection, and potential prevention of chronic diseases, including type 2 diabetes, non-alcoholic fatty liver disease (NAFLD), and cognitive decline. Epidemiological studies and randomized controlled trials consistently demonstrate that nut consumption improves lipid profiles, reduces oxidative stress, lowers inflammatory biomarkers, and...

Cytokines have emerged as pivotal regulators of communication between immune and non-immune cells, orchestrating the delicate balance between host defense, inflammation, and tissue homeostasis. Their pleiotropic effects extend far beyond immunology, influencing hematopoiesis, neuroendocrine regulation, tissue repair, and even developmental biology. This book provides a comprehensive exploration of cytokines, the small but powerful proteins that orchestrate immune regulation, inflammation, and intercellular communication. It examines the biology, classification, and mechanisms of cytokines,...

Les algues, y compris les microalgues et les macroalgues, sont des producteurs prolifiques de composés bioactifs structurellement diversifiés ayant des activités pharmacologiques étendues. Leur répertoire biochimique - polysaccharides, polyphénols, caroténoïdes, acides gras, stérols, peptides et pigments - a de puissants effets antioxydants, anti-inflammatoires, anticancéreux, immunomodulateurs, antifibrotiques et antimicrobiens. Les polysaccharides sulfatés comme le fucoidan et le carraghénane modulent les réponses immunitaires et les voies fibrotiques, tandis que les pigments...

Algen, einschließlich Mikro- und Makroalgen, sind produktive Produzenten strukturell vielfältiger bioaktiver Verbindungen mit einer breiten pharmakologischen Wirkung. Ihr biochemisches Repertoire - Polysaccharide, Polyphenole, Carotinoide, Fettsäuren, Sterole, Peptide und Pigmente - hat starke antioxidative, entzündungshemmende, krebshemmende, immunmodulatorische, antifibrotische und antimikrobielle Wirkungen. Sulfatierte Polysaccharide wie Fucoidan und Carrageenan modulieren Immunreaktionen und fibrotische Stoffwechselwege, während Pigmente wie Phycocyanin und Carotinoide wie...