Die vorliegende Studie umfasst den Entwurf und die Entwicklung einer neuartigen festen Darreichungsform mit verzögerter Freisetzung eines tuberkulosehemmenden Medikaments durch natürliche Polysaccharide. Zunächst wurde die Isolierung von Polysaccharidstudien als Entwicklungsprozess durchgeführt, bei dem die physikalischen, chemischen und mechanischen Eigenschaften eines neuen Polysaccharids durch verschiedene Parameter charakterisiert wurden. Die Isoniazid-Tabletten wurden durch Nassgranulierung unter Verwendung natürlicher Polysaccharide in verschiedenen Verhältnissen hergestellt. Das...
Die vorliegende Studie umfasst den Entwurf und die Entwicklung einer neuartigen festen Darreichungsform mit verzögerter Freisetzung eines tuberkulose...
La présente étude comprend la conception et le développement d'une nouvelle forme de dosage solide à libération prolongée d'un médicament antituberculeux par un polysaccharide naturel. Tout d'abord, l'isolement des études sur les polysaccharides a été effectué en tant que processus de développement où les propriétés physiques, chimiques et mécaniques d'un nouveau polysaccharide ont été caractérisées par différents paramètres. Les comprimés d'Isoniazide ont été préparés par la méthode de granulation humide en utilisant des polysaccharides naturels à différents...
La présente étude comprend la conception et le développement d'une nouvelle forme de dosage solide à libération prolongée d'un médicament antit...
Bilayer tablet has been made and evaluated. For various precompression and post compression parameter. Precompression parameter shows that the granules and blends of repaglinide and saxagliptin have good Carr's index and hausner's ratio indicate that both granules and blends were free flowing. The angle of repose shows that granules and blends have excellent flow and post compression parameter show that bilayer tablet have thickness hardness and weight and friability within the I. P. limit and bilayer tablet have swelling index 82% in 6 hrs and have drug release first layer of saxagliptin...
Bilayer tablet has been made and evaluated. For various precompression and post compression parameter. Precompression parameter shows that the granule...
The preformulation studies involves description, solubility, melting point, of the drug were found to be comparable with the standard. Based on the all above preformulation studies the drug was suitable for making the transdermal formulation. Based on all these factors the transdermal drug delivery system F5 was having greater % drug release. The formulation F5 shows better extended release up to 24hrs when compared to other formulations. So it was concluded that the formulation F5 prepared by using Eudragit RS100 and HPMC is the better formulation for control release of drug up to 24hrs of...
The preformulation studies involves description, solubility, melting point, of the drug were found to be comparable with the standard. Based on the al...
In the present research work, an attempt has been made to optimize and formulate bilayer tablet of saxagliptin and repaglinide to achieve immediate release of saxagliptin and sustained release of repaglinide.Saxagliptin is DPP-4 inhibitor and belonging to BCS class 1 (high solubility, high permeability). It has long half life, so an attempt was made to achieve its fast action by making immediate release tablet by using superdisintegrant sodium starch glycolate..Repaglinide is an oral blood glucose-lowering drug of the maglitinide class used in the management of type 2 diabetes mellitus. It is...
In the present research work, an attempt has been made to optimize and formulate bilayer tablet of saxagliptin and repaglinide to achieve immediate re...
