Immunosuppression is one of the most common reasons for the failure of immune-system to control tumor progression. Circulating immune-complexes (CICs) are one of the major contributing factors to induce as well as to maintain immune-suppression in tumor bearing host. Removal of CICs can reduce the burden of immunosuppressive factors, which helps to achieve immunopotentiation and anti-tumor effect. Protein A (PA) of Staphylococcus aureus Cowan I (SAC), is well known to bind with CICs more efficiently compared to immunoglobulins. Therefore, PA of SAC is used to remove CICs from ascites fluid...