The book involves a research work towards developing a formulation of anti-osteoporotic drug, which has in-vitro dissolution profile similar to that of the Innovators' formulation. The patents for dosage form of Raloxifene will expire in late future. Hence, our target was to develop a dosage form as that of Innovator product to file an ANDA application. The present study involves the development of a non-infringing formula for an orally administrable immediate release tablet of the anti-osteoporotic drug with reproducible and robust process. The objectives of the research work included (i)...
The book involves a research work towards developing a formulation of anti-osteoporotic drug, which has in-vitro dissolution profile similar to that o...
The use of antihypertensive agents in combination is common. To decrease the pill burden, lower the prescription costs and improve patient compliance; combination antihypertensive therapies compile two or more active drugs. Thiazide diuretics are frequently recommended as one of the first-line therapy for the treatment of hypertension in combination with other class of antihypertensive drugs, i.e. angiotensin-converting enzyme inhibitor, angiotensin receptor blocker, calcium channel blocker and beta-blocker. The book demonstrates strategies employed in simultaneous analysis of amlodipine,...
The use of antihypertensive agents in combination is common. To decrease the pill burden, lower the prescription costs and improve patient compliance;...
L'utilisation d'agents antihypertenseurs en association est courante. Pour diminuer le nombre de comprimés, réduire les coûts de prescription et améliorer l'observance du traitement par le patient, les thérapies antihypertensives combinées associent deux ou plusieurs médicaments actifs. Les diurétiques thiazidiques sont fréquemment recommandés comme l'un des traitements de première intention de l'hypertension en association avec d'autres classes de médicaments antihypertenseurs, à savoir les inhibiteurs de l'enzyme de conversion de l'angiotensine, les bloqueurs des récepteurs de...
L'utilisation d'agents antihypertenseurs en association est courante. Pour diminuer le nombre de comprimés, réduire les coûts de prescription et am...
Die Verwendung von antihypertensiven Wirkstoffen in Kombination ist üblich. Um die Pillenlast zu verringern, die Verschreibungskosten zu senken und die Patientencompliance zu verbessern, werden bei antihypertensiven Kombinationstherapien zwei oder mehr Wirkstoffe zusammengestellt. Thiazid-Diuretika werden häufig als eine der First-Line-Therapien zur Behandlung der Hypertonie in Kombination mit anderen Klassen von Antihypertensiva empfohlen, d.h. Angiotensin-Converting-Enzym-Hemmer, Angiotensin-Rezeptorblocker, Kalziumkanalblocker und beta-Blocker. Das Buch zeigt Strategien zur simultanen...
Die Verwendung von antihypertensiven Wirkstoffen in Kombination ist üblich. Um die Pillenlast zu verringern, die Verschreibungskosten zu senken und d...
Analytical methods development and validation play important roles in the discovery, development, and manufacture of pharmaceuticals. The current good manufacturing practice (cGMP) and Food Drug Administration (FDA) Guidelines insist for adoption of sound methods of analysis with greater sensitivity and reproducibility. This thesis describes analytical methods developed for drug determination in pharmaceutical dosage forms and biological matrixes including Chromatography (RP-HPLC) and Hyphenated Techniques (LC-MS/MS). Methods have been developed for separation and quantification of selected...
Analytical methods development and validation play important roles in the discovery, development, and manufacture of pharmaceuticals. The current good...
