This book provides essential information on improving protein folding/stability, which is a result of the balance between the intra-molecular interactions of protein functional groups and their interactions with the solvent environment. The protein folding solvent environment mainly consists of salts, small molecule compounds, metabolites, molecular chaperones and other chemical species. Therefore, subtle change in the composition of the environment will alter the protein folding process. The importance of the solvent environment in protein folding is precisely due to the fact that various...

Protein Modificomics: From Modification to Clinical Applications comprehensively deals with all of the most recent aspects of post-translational modification (PTM) of proteins including diseases involving PTM's, plant PTM's, role of therapeutic strategies and other topics such as translational proteomics.

PTMs make the major backbone of several key biological processes. It has been known that many proteins often undergo unwanted modifications leading to the disruption of proteostasis and ultimately gain in disease etiology. These diseases include Alzheimer's, Huntington's,...