In spite of the availability of multi-bullet effective chemotherapy and BCG vaccine, tuberculosis is leading infectious killer globally. TB kills about 2 million people per year. At present, approximately one-third of the world's population is infected with Mycobacterium tuberculosis and new infections occur @ one individual per second. There are several reasons that are responsible for such havoc despite the multidrug regimens. These include drug resistance, development of latency, patient non-compliance, delay in diagnosis, variable efficacy of BCG vaccine and co-infection with HIV etc.The...