Silica is one of the most documented workplace contaminants. Multiple serious diseases and increased mortality have been associated with exposure to silica, making it a high priority public health concern in developing and developed nations. Silica intoxication particularly pulmonarytoxicity, genotoxicity and carcinogenicity is widely known. We have designed a non invasive method to determine the respiratory variables of unanesthetized rodents. Despite many years of research we are still far away from effective treatment against toxicity caused due to silica exposure. This review attempts a...

Silica is one of the most ubiquitous minerals and a basic component of sand, quartz and granite rock. Multiple serious diseases and increased mortality have been associated with exposure to silica, making it a high priority public health concern. Occupational exposure silica exposure and its related health effects rank among the most important public health concerns in developing and developed nations. Silica intoxication particularly hepatotoxicity, pulmonarytoxicity, nephrotoxicity and genotoxicity is widely known. Despite many years of research we are still far away from effective...

D-Galactosamine (D-GaIN) has been shown to produce a liver damage closely related to human viral hepatitis with necrosis, inflammation and regeneration. Hepatotoxicity is one of the common diseased conditions leading to serious consequences ranging from metabolic disorders to even death. Management of liver diseases is still a great challenge to the modern medicine. At present only a few hepatoprotective drugs from natural sources are available and there is lack of effective allopathic medication available for treatment of liver disorders. We evaluated therapeutic potential of ethanolic...