The present study was designed to investigate the antiglycation potential of hydro-alcoholic and alkaloidal fractions of selected plants. Seeds of Trigonella foenum-graecum, bulbs of Allium sativum, fruits of Momordica charantia. and leaves of Gymnema sylvestre were selected. The protein glycation inhibitory activity of these plants was evaluated using glucose-bovine serum albumin assay. Among the hydroalcoholic extracts, Trigonella-foenum graecum showed highest antiglycation activity (IC50 = 53.53 1.24 ug/ml) followed by Allium sativum (IC50 = 68.36 1.56 ug/ml), Momordica charantia (IC50 =...

Experimental stress in both animals and in humans is essential to understand the basic pathophysiology of stress-related disorders. The present book attempts to clarify the basic and fundamental aspects of experimental stress in both preclinical & clinical studies. The main feature of this book is that experimental protocols, and stress assessment at behavioral and biochemical levels are described in detail. Furthermore, the pathophysiology of stress is also described in detailed manner.

Ischemia-reperfusion injury is the major cause of organ dysfunction especially in cardiovascular diseases; therefore, experimental techniques to induce myocardial ischemia-reperfusion injury are necessary to understand the basic pathophysiology of cardiovascular-related disorders. The present book attempts to illustrate the basic and fundamental aspects of ischemia-reperfusion injury in preclinical and clinical studies. The key features of this book are various experimental techniques to induce myocardial ischemia-reperfusion injury, various parameters to assess myocardial injury, therapeutic...