Garlic (Allium sativum L., Liliaceae) is a nature's boon to mankind which has played an important dietary and therapeutic medicinal role throughout the history of mankind. Aluminum is a potent neurotoxin and has been associated with Alzheimer's disease causality for decades. Study demonstrated the ameliorative effect of garlic extract against aluminium-induced toxicity in rat model. Results reveal dose dependent response with the administration of therapeutic agent. Treatment with extract of Garlic revealed that it was significantly effective in recouping most of the biochemical alterations...

Today many medicinal plant species of India have reached the fate of extinction of severe toxicity of liver and kidney. Unfortunately detailed information and complete inventions on such plats often do not exist. For most of the endangered species, no conservation efforts have been implemented and a lion's share of the knowledge on their properties and use are held exclusively by traditional healer societies, whose very existence is now under threat. The aim of this book in the study of ploygonum bistorta is a herbal plant is used against over doses of paracetamol toxicity in liver and...

Sprirulina extract enrich in phenolic antioxidants may provide a promising source of natural antioxidant. Thus, crude organic extracts of S.splatensis possessed strongest free radical scavenging activity. This finding suggests that the presence of electron and/or hydrogen donating constituent in algal organic extracts such as phycocyanin, carotenoid and phenol compounds. However, the positive correlations between phenol, phytosterol and carotenoids contents in Sprirulina and its antioxidant activity is also well documented .Total phenolic, phycocynin, carotenoids and chlorophyll-derived...

Silica is one of the most documented workplace contaminants. Multiple serious diseases and increased mortality have been associated with exposure to silica, making it a high priority public health concern in developing and developed nations. Silica intoxication particularly pulmonarytoxicity, genotoxicity and carcinogenicity is widely known. We have designed a non invasive method to determine the respiratory variables of unanesthetized rodents. Despite many years of research we are still far away from effective treatment against toxicity caused due to silica exposure. This review attempts a...

Silica is one of the most ubiquitous minerals and a basic component of sand, quartz and granite rock. Multiple serious diseases and increased mortality have been associated with exposure to silica, making it a high priority public health concern. Occupational exposure silica exposure and its related health effects rank among the most important public health concerns in developing and developed nations. Silica intoxication particularly hepatotoxicity, pulmonarytoxicity, nephrotoxicity and genotoxicity is widely known. Despite many years of research we are still far away from effective...

D-Galactosamine (D-GaIN) has been shown to produce a liver damage closely related to human viral hepatitis with necrosis, inflammation and regeneration. Hepatotoxicity is one of the common diseased conditions leading to serious consequences ranging from metabolic disorders to even death. Management of liver diseases is still a great challenge to the modern medicine. At present only a few hepatoprotective drugs from natural sources are available and there is lack of effective allopathic medication available for treatment of liver disorders. We evaluated therapeutic potential of ethanolic...

Our current investigation verifies for the first time, the protective effects of Polygonum bistorta and Tannic Acid against model hepatotoxicant in rats. The hepatoprotective action is likely related to its potent antioxidative and anti-inflammatory activity. Neutralizing reactive oxygen species by non enzymatic mechanism and enhancing the activity of original natural hepatic antioxidants enzymes may be the main mechanisms against injury. These data provide a scientific explanation for the folkloric uses of Polygonum bistorta and tannic acid in the treatments of hepatic disorders. The...