Bioadhesive polymers that bind to the gastric mucin or epithelial cell surface are useful in drug delivery for the purpose of (a) retaining a dosage form in the G.I tract and (b) increasing the intimacy and duration of contact of drug with the absorbing membrane. In this investigation, natural mucoadhesive materials were isolated from different edible fruits like Aegle marmelos (Linn.) Cor., Zizyphus mauritiana and Tamarindus indica by hot extraction method. Density and swelling property of natural materials were evaluated. Bioadhesive and mucoadhesive qualities of natural materials were...