Heterocyclic compounds have been well researched and still continue to provide solutions to innumerable problems faced by mankind. One of such problems is increasing resistance of microbes against existing antibiotics. Often, infection is found to be associated with inflammation. 1, 3, 4-oxadiazoles have been explored by a number of scientists worldwide these derivatives have emerged as potential lead molecules for development of newer antimicrobial and anti-inflammatory agents. The present work reports the synthesis and evaluation of some 2, 5-disubstituted 1, 3, 4-oxadiazoles and their...

The concern today is not to just to produce elegant and accurate dosage forms but also to ensure that optimum amount of drug reaches the target site at an optimal rate and its concentration is maintained for the entire duration of therapy. The twin disciplines of Pharmacodynamics and Pharmacokinetics have, therefore, been developed with the object of learning how drug can be utilized optimally in the treatment of disease-through design and development of new and better delivery systems. The major objective of writing this book is to present the information of formulation, optimization,...