Mammalian oocytes occupy a critical nexus in reproduction as they not only contribute half the genetic makeup of the embryo but also provide virtually all of the cytoplasmic building blocks required for sustaining embryogenesis. The journey that transforms a primordial germ cell into a mature oocyte (or egg) capable of fertilisation and embryonic development is of unrivalled complexity. The end-product of this remarkable developmental process is the mature egg, now replete with macromolecules and organelles, and poised to support embryonic development if fertilisation should occur. Given...
Mammalian oocytes occupy a critical nexus in reproduction as they not only contribute half the genetic makeup of the embryo but also provide virtua...
This Methods in Molecular Biology (TM) volume offers methodologies enabling researchers to interrogate every aspect of mammalian oocyte development including recombination, meiotic maturation, oocyte substrate uptake, chromosomal segregation and fertilisation.
This Methods in Molecular Biology (TM) volume offers methodologies enabling researchers to interrogate every aspect of mammalian oocyte development in...
