The central problem of modern hepatology is identification of a regional hepatic stem cell. Necessity of solving this problem is dictated by considerable prevalence of chronic liver diseases, insufficient efficiency of existing methods of their treatment, and as a consequence - by high frequency of liver fibrosis and cirrhosis development as an outcome of these diseases. Liver transplantation becomes the only possible method of treatment in these cases. However existing deficiency of donor organs, long waiting lists, high cost of transplantation and necessity of subsequent immunosuppression...