The first oral contraceptive became available in 1960 and since then these sub stances, which have been used by millions of women, have probably been the most widely studied group of drugs in medical history (Drill, 1966, 1977). Part of the evaluation oCoral contraceptives has involved their effect on the reproductive organs of women, with particular attention directed to evaluation of a possible carcinogenic effect of these steroids. To the extent that cancer of the reproductive organs is a common finding in women, the endogenous female sex hormones have been implicated in the occur rence of...
The first oral contraceptive became available in 1960 and since then these sub stances, which have been used by millions of women, have probably been ...