This volume demonstrates the great progress made since the first successful allogeneic marrow transplants were performed in man over twenty years ago and also confronts today's unresolved significant problems. These include acute and chronic graft-versus-host disease, infection after bone marrow transplantation, and leukemic relapses. Discussion of experimental bone marrow transplantation focuses on such topics as the following: failure of self/nonself discrimination, prevention of transfusion-induced sensitization in marrow transplant recipients, bone marrow purging with chemical and...
This volume demonstrates the great progress made since the first successful allogeneic marrow transplants were performed in man over twenty years ago ...
In the last decade, remarkable advances have been made in bone marrow transplantation (BMT), which is now becoming a powerful tool in the treatment of diseases such as leukemia, aplastic anemia, and congenital immunodeficiency. In animal experiments, it has been found that BMT can be used to treat not only systemic autoimmune diseases but also organ-specific autoimmune diseases. In humans, it has recently been shown that rheumatoid arthritis, ulcerative colitis, and Crohn's disease can be successfully treated after BMT. This volume contains new information on how to prevent graft rejection,...
In the last decade, remarkable advances have been made in bone marrow transplantation (BMT), which is now becoming a powerful tool in the treatment of...