Nowadays there are many available molecular methods for studying diseases. Archival tissue provides an extremely valuable material for proper understanding of pathology of various diseases. A major problem in molecular analysis of archival tissues is the tissue degradation that might occur during long storage. This monograph presents various methods for efficient extraction of DNA and protocols for sequencing (detection of gene mutations) from archival tissues. It also provides protocols for immunodetection of various proteins on such archival tissues collected at Gades Institute, Haukeland...