Ample information suggests multileveled relationships between long-term psychological stress responses and alternative splicing - the process which yields different mRNAs from the same gene. However, the nature of these relationships remains unclear. Eran Meshorer studied the stress-induced changes in alternative splicing at Hermona Soreqs lab and shed light on the molecular pathways that lead to such responses. Meshorer focused on a particular mRNA - acetylcholinesterase (AChE), which is neuronally-expressed, stress-responsive, and yields alternatively spliced products, thus serving as...
Ample information suggests multileveled relationships between long-term psychological stress responses and alternative splicing - the process ...
Stem cells have been gaining a lot of attention in recent years. Their unique potential to self-renew and differentiate has turned them into an attractive model for the study of basic biological questions such as cell division, replication, transcription, cell fate decisions, and more. With embryonic stem (ES) cells that can generate each cell type in the mammalian body and adult stem cells that are able to give rise to the cells within a given lineage, basic questions at different developmental stages can be addressed. Importantly, both adult and embryonic stem cells provide an excellent...
Stem cells have been gaining a lot of attention in recent years. Their unique potential to self-renew and differentiate has turned them into an attrac...