Multicellular organisms must be able to adapt to cellular events to accommodate prevailing conditions. Sensory-response circuits operate by making use of a phosphorylation control mechanism known as the "two-component system."

Sections include:
Computational Analyses of Sequences and Sequence Alignments
Biochemical and Genetic Assays of Individual Components of Signaling Systems
Physiological Assays and Readouts

• Presents detailed protocols
• Includes troubleshooting tips

Multicellular organisms must be able to adapt to cellular events to accommodate prevailing conditions. Sensory-response circuits operate by making use of a phosphorylation control mechanism known as the "two-component system."

Sections in Two-Component Signaling Systems, Part B include:

• Structural Approaches
• Reconstitution of Heterogeneous Systems
• Intracellular Methods and Assays
• Genome-Wide Analyses of Two-Component Systems

• Presents detailed protocols
• Includes troubleshooting tips