The role of reactive oxygen species (ROS) in the cardiovascular system is Jan- faced. Whereas low concentrations of ROS are involved in variety of physiological signalling events, oxidative stress resulting from deregulated overproduction of ROS and/or impaired antioxidant defences contributes to cardiovascular disease. The actions of ROS in the cardiovascular system are a fascinating topic, not only for the basic science researcher but also for the clinician who is interested in seeking new therapies for his patients suffering from cardiovascular disease. The current book provides a...

1.1 Pathogenetische Aspekte Dem Diabetes mellitus liegt eine chronische Storung des Kohlenhy drat- und auch des Fett- und Eiweissstoffwechsels zugrunde. Ursa chen sind ein absoluter oder relativer Mangel an Insulin, bei vielen ubergewichtigen Patienten ausserdem eine herabgesetzte Insulin empfindlichkeit der Gewebe, so dass die blutzuckersenkende Wir kung des Hormons vermindert ist. Die zentrale Bedeutung der Bauchspeicheldruse bzw. des Insulin mangels fur die Zuckerkrankheit wurde deutlich, nachdem Mering und Minkowski bei Hunden durch Pankreatektomie einen Diabetes erzeugten und spater...

The role of reactive oxygen species (ROS) in the cardiovascular system is Jan- faced. Whereas low concentrations of ROS are involved in variety of physiological signalling events, oxidative stress resulting from deregulated overproduction of ROS and/or impaired antioxidant defences contributes to cardiovascular disease. The actions of ROS in the cardiovascular system are a fascinating topic, not only for the basic science researcher but also for the clinician who is interested in seeking new therapies for his patients suffering from cardiovascular disease. The current book provides a...